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Clinical Pharmacokinetics of Therapeutic Monoclonal Antibodies

Clinical pharmacokinetics, 2010-08, Vol.49 (8), p.493-507

2010

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Practical Guidelines for Therapeutic Drug Monitoring of Anticancer Tyrosine Kinase Inhibitors: Focus on the Pharmacokinetic Targets

Clinical pharmacokinetics, 2014-04, Vol.53 (4), p.305-325

2014

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Oral Anticancer Drugs: Mechanisms of Low Bioavailability and Strategies for Improvement

Clinical pharmacokinetics, 2013-06, Vol.52 (6), p.399-414

2013

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ABCB1, ABCG2, and PTEN Determine the Response of Glioblastoma to Temozolomide and ABT-888 Therapy

Clinical cancer research, 2014-05, Vol.20 (10), p.2703-2713

2014

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Quantitative bioanalysis of peptides by liquid chromatography coupled to (tandem) mass spectrometry

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2008-09, Vol.872 (1), p.1-22

2008

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A Phase I and Pharmacological Study with Imidazolium-trans-DMSO-imidazole-tetrachlororuthenate, a Novel Ruthenium Anticancer Agent

Clinical cancer research, 2004-06, Vol.10 (11), p.3717-3727

2004

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P-Glycoprotein and Breast Cancer Resistance Protein: Two Dominant Transporters Working Together in Limiting the Brain Penetration of Topotecan

Clinical cancer research, 2007-11, Vol.13 (21), p.6440-6449

2007

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Relevance of in vitro and clinical data for predicting CYP3A4-mediated herb–drug interactions in cancer patients

Cancer treatment reviews, 2013-11, Vol.39 (7), p.773-783

2013

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Effect of inhibition of the FGFR–MAPK signaling pathway on the development of ocular toxicities

Cancer treatment reviews, 2013-10, Vol.39 (6), p.664-672

2013

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Bioequivalence of Liposome-Entrapped Paclitaxel Easy-To-Use (LEP-ETU) Formulation and Paclitaxel in Polyethoxylated Castor Oil: A Randomized, Two-Period Crossover Study in Patients With Advanced Cancer

Clinical therapeutics, 2013-12, Vol.35 (12), p.1946-1954

2013

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Optimal Dosing of Miltefosine in Children and Adults with Visceral Leishmaniasis

Antimicrobial Agents and Chemotherapy, 2012-07, Vol.56 (7), p.3864-3872

2012

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Management of Hot Flashes in Patients Who Have Breast Cancer With Venlafaxine and Clonidine: A Randomized, Double-Blind, Placebo-Controlled Trial

Journal of clinical oncology, 2011-10, Vol.29 (29), p.3862-3868

2011

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Clinical pharmacokinetics of cyclophosphamide

Clinical pharmacokinetics, 2005-01, Vol.44 (11), p.1135-1164

2005

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Brain Accumulation of Dasatinib Is Restricted by P-Glycoprotein (ABCB1) and Breast Cancer Resistance Protein (ABCG2) and Can Be Enhanced by Elacridar Treatment

Clinical cancer research, 2009-04, Vol.15 (7), p.2344-2351

2009

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Differential impact of P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) on axitinib brain accumulation and oral plasma pharmacokinetics

Drug metabolism and disposition, 2011-05, Vol.39 (5), p.729-735

2011

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MRP2 (ABCC2) transports taxanes and confers paclitaxel resistance and both processes are stimulated by probenecid

International journal of cancer, 2005-09, Vol.116 (5), p.824-829

2005

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Quantitative assay for six potential breast cancer biomarker peptides in human serum by liquid chromatography coupled to tandem mass spectrometry

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2010-02, Vol.878 (5), p.590-602

2010

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P-glycoprotein (P-gp/Abcb1), Abcc2, and Abcc3 Determine the Pharmacokinetics of Etoposide

Clinical cancer research, 2010-01, Vol.16 (1), p.130-140

2010

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P-Glycoprotein, CYP3A, and Plasma Carboxylesterase Determine Brain and Blood Disposition of the mTOR Inhibitor Everolimus (Afinitor) in Mice

Clinical cancer research, 2014-06, Vol.20 (12), p.3133-3145

2014

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Electrospray Ionization Quadrupole Ion-Mobility Time-of-Flight Mass Spectrometry as a Tool to Distinguish the Lot-to-Lot Heterogeneity in N-Glycosylation Profile of the Therapeutic Monoclonal Antibody Trastuzumab

Journal of the American Society for Mass Spectrometry, 2009-11, Vol.20 (11), p.2021-2033

2009

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A Phase I, Randomized, Open-Label, Parallel-Cohort, Dose-Finding Study of Elacridar (GF120918) and Oral Topotecan in Cancer Patients

Clinical cancer research, 2007-06, Vol.13 (11), p.3276-3285

2007

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Pharmacokinetics of Miltefosine in Old World Cutaneous Leishmaniasis Patients

Antimicrobial Agents and Chemotherapy, 2008-08, Vol.52 (8), p.2855-2860

2008

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Miltefosine: a review of its pharmacology and therapeutic efficacy in the treatment of leishmaniasis

Journal of antimicrobial chemotherapy, 2012-11, Vol.67 (11), p.2576-2597

2012

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Phase I and pharmacokinetic trial of AP5346, a DACH-platinum-polymer conjugate, administered weekly for three out of every 4 weeks to advanced solid tumor patients

Cancer chemotherapy and pharmacology, 2007-09, Vol.60 (4), p.523-533

2007

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Influence of polymorphisms of drug metabolizing enzymes (CYP2B6, CYP2C9, CYP2C19, CYP3A4, CYP3A5, GSTA1, GSTP1, ALDH1A1 and ALDH3A1) on the pharmacokinetics of cyclophosphamide and 4-hydroxycyclophosphamide

Pharmacogenetics and genomics, 2008-06, Vol.18 (6), p.515-523

2008

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Clinical Pharmacokinetics of Therapeutic Monoclonal Antibodies

Practical Guidelines for Therapeutic Drug Monitoring of Anticancer Tyrosine Kinase Inhibitors: Focus on the Pharmacokinetic Targets

Oral Anticancer Drugs: Mechanisms of Low Bioavailability and Strategies for Improvement

ABCB1, ABCG2, and PTEN Determine the Response of Glioblastoma to Temozolomide and ABT-888 Therapy

Quantitative bioanalysis of peptides by liquid chromatography coupled to (tandem) mass spectrometry

A Phase I and Pharmacological Study with Imidazolium-trans-DMSO-imidazole-tetrachlororuthenate, a Novel Ruthenium Anticancer Agent

P-Glycoprotein and Breast Cancer Resistance Protein: Two Dominant Transporters Working Together in Limiting the Brain Penetration of Topotecan

Relevance of in vitro and clinical data for predicting CYP3A4-mediated herb–drug interactions in cancer patients

Effect of inhibition of the FGFR–MAPK signaling pathway on the development of ocular toxicities

Bioequivalence of Liposome-Entrapped Paclitaxel Easy-To-Use (LEP-ETU) Formulation and Paclitaxel in Polyethoxylated Castor Oil: A Randomized, Two-Period Crossover Study in Patients With Advanced Cancer

Optimal Dosing of Miltefosine in Children and Adults with Visceral Leishmaniasis

Management of Hot Flashes in Patients Who Have Breast Cancer With Venlafaxine and Clonidine: A Randomized, Double-Blind, Placebo-Controlled Trial

Clinical pharmacokinetics of cyclophosphamide

Brain Accumulation of Dasatinib Is Restricted by P-Glycoprotein (ABCB1) and Breast Cancer Resistance Protein (ABCG2) and Can Be Enhanced by Elacridar Treatment

Differential impact of P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) on axitinib brain accumulation and oral plasma pharmacokinetics

MRP2 (ABCC2) transports taxanes and confers paclitaxel resistance and both processes are stimulated by probenecid

Quantitative assay for six potential breast cancer biomarker peptides in human serum by liquid chromatography coupled to tandem mass spectrometry

P-glycoprotein (P-gp/Abcb1), Abcc2, and Abcc3 Determine the Pharmacokinetics of Etoposide

P-Glycoprotein, CYP3A, and Plasma Carboxylesterase Determine Brain and Blood Disposition of the mTOR Inhibitor Everolimus (Afinitor) in Mice

Electrospray Ionization Quadrupole Ion-Mobility Time-of-Flight Mass Spectrometry as a Tool to Distinguish the Lot-to-Lot Heterogeneity in N-Glycosylation Profile of the Therapeutic Monoclonal Antibody Trastuzumab

A Phase I, Randomized, Open-Label, Parallel-Cohort, Dose-Finding Study of Elacridar (GF120918) and Oral Topotecan in Cancer Patients

Pharmacokinetics of Miltefosine in Old World Cutaneous Leishmaniasis Patients

Miltefosine: a review of its pharmacology and therapeutic efficacy in the treatment of leishmaniasis

Phase I and pharmacokinetic trial of AP5346, a DACH-platinum-polymer conjugate, administered weekly for three out of every 4 weeks to advanced solid tumor patients

Influence of polymorphisms of drug metabolizing enzymes (CYP2B6, CYP2C9, CYP2C19, CYP3A4, CYP3A5, GSTA1, GSTP1, ALDH1A1 and ALDH3A1) on the pharmacokinetics of cyclophosphamide and 4-hydroxycyclophosphamide

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