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Role of CYP2B6 and CYP3A4 in the in vitro N-dechloroethylation of (R)- and (S)-ifosfamide in human liver microsomes

Drug metabolism and disposition, 1999-04, Vol.27 (4), p.533

1999

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Efficacy and toxicity of ifosfamide stereoisomers in an in vivo rat mammary carcinoma model

Cancer research (Chicago, Ill.), 1994-08, Vol.54 (16), p.4393-4397

1994

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Phenytoin-induced alteration in the N-dechloroethylation of ifosfamide stereoisomers

Cancer chemotherapy and pharmacology, 1997, Vol.40 (6), p.531-533

1997

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The N-dechloroethylation of ifosfamide : using stereochemistry the obtain an accurate picture of a clinically relevant metabolic pathway

Cancer chemotherapy and pharmacology, 1996, Vol.37 (4), p.332-336

1996

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Influence of phenobarbital induction on the enantioselective N-dechloroethylation of ifosfamide enantiomers in the rat

Drug metabolism and disposition, 1994-01, Vol.22 (1), p.165

1994

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Stereoselective separations of chiral anticancer drugs and their application to pharmacodynamic and pharmacokinetic studies

Therapeutic drug monitoring, 1993-12, Vol.15 (6), p.570-575

1993

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Stereoselective pharmacokinetics of ifosfamide and its 2- and 3-N-dechloroethylated metabolites in female cancer patients

Cancer chemotherapy and pharmacology, 1996, Vol.37 (5), p.451-456

1996

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Expression of the human CYP3A4 gene in the small intestine of transgenic mice: in vitro metabolism and pharmacokinetics of midazolam

Drug metabolism and disposition, 2003-05, Vol.31 (5), p.548-558

2003

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Determination of 4-hydroxyifosfamide concomitantly with ifosfamide and its dechloroethylated metabolites using gas chromatography and a nitrogen phosphorus-selective detector

Journal of chromatography. B, Biomedical sciences and applications, 1999-09, Vol.732 (1), p.3-15

1999

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A Phase I, Multicenter, Open-Label, First-in-Human, Dose-Escalation Study of the Oral Smoothened Inhibitor Sonidegib (LDE225) in Patients with Advanced Solid Tumors

Clinical cancer research, 2014-04, Vol.20 (7), p.1900-1909

2014

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Quantitative determination of besifloxacin, a novel fluoroquinolone antimicrobial agent, in human tears by liquid chromatography–tandem mass spectrometry

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2008-05, Vol.867 (1), p.105-110

2008

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New insights into the pharmacokinetics and metabolism of (R, S)-ifosfamide in cancer patients using a population pharmacokinetic-metabolism model

Pharmaceutical research, 2000-06, Vol.17 (6), p.645-652

2000

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Prilocaine-induced methemoglobinemia in a child with Shwachman syndrome

Journal of oral and maxillofacial surgery, 1985-01, Vol.43 (8), p.621-623

1985

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Role of CYP2B6 and CYP3A4 in the in vitro N-dechloroethylation of (R)- and (S)-ifosfamide in human liver microsomes

Efficacy and toxicity of ifosfamide stereoisomers in an in vivo rat mammary carcinoma model

Phenytoin-induced alteration in the N-dechloroethylation of ifosfamide stereoisomers

The N-dechloroethylation of ifosfamide : using stereochemistry the obtain an accurate picture of a clinically relevant metabolic pathway

Influence of phenobarbital induction on the enantioselective N-dechloroethylation of ifosfamide enantiomers in the rat

Stereoselective separations of chiral anticancer drugs and their application to pharmacodynamic and pharmacokinetic studies

Stereoselective pharmacokinetics of ifosfamide and its 2- and 3-N-dechloroethylated metabolites in female cancer patients

Expression of the human CYP3A4 gene in the small intestine of transgenic mice: in vitro metabolism and pharmacokinetics of midazolam

Determination of 4-hydroxyifosfamide concomitantly with ifosfamide and its dechloroethylated metabolites using gas chromatography and a nitrogen phosphorus-selective detector

A Phase I, Multicenter, Open-Label, First-in-Human, Dose-Escalation Study of the Oral Smoothened Inhibitor Sonidegib (LDE225) in Patients with Advanced Solid Tumors

Quantitative determination of besifloxacin, a novel fluoroquinolone antimicrobial agent, in human tears by liquid chromatography–tandem mass spectrometry

New insights into the pharmacokinetics and metabolism of (R, S)-ifosfamide in cancer patients using a population pharmacokinetic-metabolism model

Prilocaine-induced methemoglobinemia in a child with Shwachman syndrome

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