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Pharmacological characterization of a novel centrally permeable P2X7 receptor antagonist: JNJ‐47965567

British journal of pharmacology, 2013-10, Vol.170 (3), p.624-640

2013

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Remdesivir triphosphate can efficiently inhibit the RNA-dependent RNA polymerase from various flaviviruses

Antiviral research, 2020-10, Vol.182, p.104899-104899, Article 104899

2020

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New dual ATP-competitive inhibitors of bacterial DNA gyrase and topoisomerase IV active against ESKAPE pathogens

European journal of medicinal chemistry, 2021-03, Vol.213, p.113200, Article 113200

2021

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P2X receptors: Insights from the study of the domestic dog

Neuropharmacology, 2023-02, Vol.224, p.109358, Article 109358

2023

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Hydroxysafflor yellow A protects against colitis in mice by suppressing pyroptosis via inhibiting HK1/NLRP3/GSDMD and modulating gut microbiota

Toxicology and applied pharmacology, 2023-05, Vol.467, p.116494-116494, Article 116494

2023

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Utilizing non-coding RNA-mediated regulation of ATP binding cassette (ABC) transporters to overcome multidrug resistance to cancer chemotherapy

Drug resistance updates, 2024-03, Vol.73, p.101058-101058, Article 101058

2024

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Structure-Based Design of Novel Alkynyl Thio-Benzoxazepinone Receptor-Interacting Protein Kinase‑1 Inhibitors: Extending the Chemical Space from the Allosteric to ATP Binding Pockets

Journal of medicinal chemistry, 2023-02, Vol.66 (4), p.3073-3087

2023

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Pharmacological characterization of a structural hybrid P2X7R antagonist using ATP and LL-37

European journal of pharmacology, 2022-01, Vol.914, p.174667-174667, Article 174667

2022

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Painful purinergic receptors

The Journal of pharmacology and experimental therapeutics, 2008-02, Vol.324 (2), p.409-415

2008

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Extracellular ATP inhibits excitatory synaptic input on parvalbumin positive interneurons and attenuates gamma oscillations via P2X4 receptors

British journal of pharmacology, 2024-06, Vol.181 (11), p.1635-1653

2024

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Pannexin-1-mediated ATP release from area CA3 drives mGlu5-dependent neuronal oscillations

Neuropharmacology, 2015-06, Vol.93, p.219-228

2015

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ATP-gated P2X cation-channels

Neuropharmacology, 2009-01, Vol.56 (1), p.208-215

2009

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Specificity of the ecto‐ATPase inhibitor ARL 67156 on human and mouse ectonucleotidases

British journal of pharmacology, 2007-09, Vol.152 (1), p.141-150

2007

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ATP ion channel P2X purinergic receptors in inflammation response

Biomedicine & pharmacotherapy, 2023-02, Vol.158, p.114205-114205, Article 114205

2023

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Isoliquiritigenin alleviates P. gingivalis-LPS/ATP-induced pyroptosis by inhibiting NF-κB/ NLRP3/GSDMD signals in human gingival fibroblasts

International immunopharmacology, 2021-12, Vol.101 (Pt B), p.108338-108338, Article 108338

2021

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Ethanol differentially modulates P2X4 and P2X7 receptor activity and function in BV2 microglial cells

Neuropharmacology, 2018-01, Vol.128, p.11-21

2018

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Neuropeptide Y facilitates P2X1 receptor-dependent vasoconstriction via Y1 receptor activation in small mesenteric arteries during sympathetic neurogenic responses

Vascular pharmacology, 2021-02, Vol.136, p.106810-106810, Article 106810

2021

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The mitochondrial complex V-associated large-conductance inner membrane current is regulated by cyclosporine and dexpramipexole

Molecular pharmacology, 2015-01, Vol.87 (1), p.1-8

2015

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Slow sulfide donor GYY4137 potentiates effect of paclitaxel on colorectal carcinoma cells

European journal of pharmacology, 2022-05, Vol.922, p.174875-174875, Article 174875

2022

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Baeckein E suppressed NLRP3 inflammasome activation through inhibiting both the priming and assembly procedure: Implications for gout therapy

Phytomedicine (Stuttgart), 2021-04, Vol.84, p.153521, Article 153521

2021

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Highly Potent and Selective Ectonucleotide Pyrophosphatase/Phosphodiesterase I Inhibitors Based on an Adenosine 5′-(α or γ)-Thio-(α,β- or β,γ)-methylenetriphosphate Scaffold

Journal of medicinal chemistry, 2014-06, Vol.57 (11), p.4677-4691

2014

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Structure-activity and mechanistic studies of non-peptidic inhibitors of the PLK1 polo box domain identified through REPLACE

European journal of medicinal chemistry, 2022-01, Vol.227, p.113926-113926, Article 113926

2022

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Nicorandil reduces morphine withdrawal symptoms, potentiates morphine antinociception, and ameliorates liver fibrosis in rats

Life sciences (1973), 2023-04, Vol.319, p.121522-121522, Article 121522

2023

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P2X receptor- and postsynaptic NMDA receptor-mediated long-lasting facilitation of inhibitory synapses in the rat insular cortex

Neuropharmacology, 2024-03, Vol.245, p.109817-109817, Article 109817

2024

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LncRNA-Meg3 promotes Nlrp3-mediated microglial inflammation by targeting miR-7a-5p

International immunopharmacology, 2021-01, Vol.90, p.107141-107141, Article 107141

2021

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Pharmacological characterization of a novel centrally permeable P2X7 receptor antagonist: JNJ‐47965567

Remdesivir triphosphate can efficiently inhibit the RNA-dependent RNA polymerase from various flaviviruses

New dual ATP-competitive inhibitors of bacterial DNA gyrase and topoisomerase IV active against ESKAPE pathogens

P2X receptors: Insights from the study of the domestic dog

Hydroxysafflor yellow A protects against colitis in mice by suppressing pyroptosis via inhibiting HK1/NLRP3/GSDMD and modulating gut microbiota

Utilizing non-coding RNA-mediated regulation of ATP binding cassette (ABC) transporters to overcome multidrug resistance to cancer chemotherapy

Structure-Based Design of Novel Alkynyl Thio-Benzoxazepinone Receptor-Interacting Protein Kinase‑1 Inhibitors: Extending the Chemical Space from the Allosteric to ATP Binding Pockets

Pharmacological characterization of a structural hybrid P2X7R antagonist using ATP and LL-37

Painful purinergic receptors

Extracellular ATP inhibits excitatory synaptic input on parvalbumin positive interneurons and attenuates gamma oscillations via P2X4 receptors

Pannexin-1-mediated ATP release from area CA3 drives mGlu5-dependent neuronal oscillations

ATP-gated P2X cation-channels

Specificity of the ecto‐ATPase inhibitor ARL 67156 on human and mouse ectonucleotidases

ATP ion channel P2X purinergic receptors in inflammation response

Isoliquiritigenin alleviates P. gingivalis-LPS/ATP-induced pyroptosis by inhibiting NF-κB/ NLRP3/GSDMD signals in human gingival fibroblasts

Ethanol differentially modulates P2X4 and P2X7 receptor activity and function in BV2 microglial cells

Neuropeptide Y facilitates P2X1 receptor-dependent vasoconstriction via Y1 receptor activation in small mesenteric arteries during sympathetic neurogenic responses

The mitochondrial complex V-associated large-conductance inner membrane current is regulated by cyclosporine and dexpramipexole

Slow sulfide donor GYY4137 potentiates effect of paclitaxel on colorectal carcinoma cells

Baeckein E suppressed NLRP3 inflammasome activation through inhibiting both the priming and assembly procedure: Implications for gout therapy

Highly Potent and Selective Ectonucleotide Pyrophosphatase/Phosphodiesterase I Inhibitors Based on an Adenosine 5′-(α or γ)-Thio-(α,β- or β,γ)-methylenetriphosphate Scaffold

Structure-activity and mechanistic studies of non-peptidic inhibitors of the PLK1 polo box domain identified through REPLACE

Nicorandil reduces morphine withdrawal symptoms, potentiates morphine antinociception, and ameliorates liver fibrosis in rats

P2X receptor- and postsynaptic NMDA receptor-mediated long-lasting facilitation of inhibitory synapses in the rat insular cortex

LncRNA-Meg3 promotes Nlrp3-mediated microglial inflammation by targeting miR-7a-5p

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