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Interactions of the antioxidant enzymes NAD(P)H: Quinone oxidoreductase 1 (NQO1) and NRH: Quinone oxidoreductase 2 (NQO2) with pharmacological agents, endogenous biochemicals and environmental contaminants

Chemico-biological interactions, 2021-08, Vol.345, p.109574-109574, Article 109574

2021

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Isoniazid and host immune system interactions: A proposal for a novel comprehensive mode of action

British journal of pharmacology, 2019-12, Vol.176 (24), p.4599-4608

2019

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The Interaction of Myeloperoxidase with the Industrial Contaminant 6‑PPD: A Potential Pathway for Reactive Metabolites

Chemical research in toxicology, 2024-10, Vol.37 (10), p.1738-1746

2024

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Introduction to the special issue from the 10th meeting of the Canadian Oxidative Stress Consortium

Chemico-biological interactions, 2019-10, Vol.312, p.108800-108800, Article 108800

2019

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Comparing the oxidative functions of neutrophil myeloperoxidase and cytochrome P450 enzymes in drug metabolism

Chemico-biological interactions, 2024-04, Vol.392, p.110942-110942, Article 110942

2024

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Caution for the routine use of phenol red – It is more than just a pH indicator

Chemico-biological interactions, 2019-09, Vol.310, p.108739-108739, Article 108739

2019

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Eosinophil peroxidase oxidizes isoniazid to form the active metabolite against M. tuberculosis, isoniazid-NAD

Chemico-biological interactions, 2019-05, Vol.305, p.48-53

2019

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Scavenging of Free-Radical Metabolites of Aniline Xenobiotics and Drugs by Amino Acid Derivatives: Toxicological Implications of Radical-Transfer Reactions

Chemical research in toxicology, 2013-12, Vol.26 (12), p.1872-1883

2013

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Current status and future prospects of toxicogenomics in drug discovery

Drug discovery today, 2014-05, Vol.19 (5), p.562-578

2014

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Phenylbutazone Oxidation via Cu,Zn-SOD Peroxidase Activity: An EPR Study

Chemical research in toxicology, 2015-07, Vol.28 (7), p.1476-1483

2015

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Metabolism of isoniazid by neutrophil myeloperoxidase leads to isoniazid-NAD+ adduct formation: A comparison of the reactivity of isoniazid with its known human metabolites

Biochemical pharmacology, 2016-04, Vol.106, p.46-55

2016

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Proteomic profile of aminoglutethimide-induced apoptosis in HL-60 cells: Role of myeloperoxidase and arylamine free radicals

Chemico-biological interactions, 2015-09, Vol.239, p.129-138

2015

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Anti-inflammatory and antioxidant properties of a novel resveratrol–salicylate hybrid analog

Bioorganic & medicinal chemistry letters, 2016-03, Vol.26 (5), p.1411-1415

2016

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The interaction of diamines and polyamines with the peroxidase-catalyzed metabolism of aromatic amines: a potential mechanism for the modulation of aniline toxicity

Canadian journal of physiology and pharmacology, 2013-03, Vol.91 (3), p.228-235

2013

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Cytoprotective effect of isoniazid against H2O2 derived injury in HL-60 cells

Chemico-biological interactions, 2016-01, Vol.244, p.37-48

2016

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The effect of bicarbonate on menadione-induced redox cycling and cytotoxicity: potential involvement of the carbonate radical

Canadian journal of physiology and pharmacology, 2013-10, Vol.91 (10), p.783-790

2013

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Investigating the Mechanisms of Aromatic Amine-Induced Protein Free Radical Formation by Quantitative Structure−Activity Relationships: Implications for Drug-Induced Agranulocytosis

Chemical research in toxicology, 2010-05, Vol.23 (5), p.880-887

2010

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Molecular cytotoxic mechanisms of anticancer hydroxychalcones

Chemico-biological interactions, 2004-06, Vol.148 (1), p.57-67

2004

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Aminoglutethimide-Induced Protein Free Radical Formation on Myeloperoxidase: A Potential Mechanism of Agranulocytosis

Chemical research in toxicology, 2007-07, Vol.20 (7), p.1038-1045

2007

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Induction of quinone oxidoreductase 1 enzyme by Rhazya stricta through Nrf2-dependent mechanism

Journal of ethnopharmacology, 2012-11, Vol.144 (2), p.416-424

2012

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Application of quantitative structure–toxicity relationships for acute NSAID cytotoxicity in rat hepatocytes

Chemico-biological interactions, 2005-02, Vol.151 (3), p.177-191

2005

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Reversing T-cell exhaustion in immunotherapy: a review on current approaches and limitations

Expert opinion on therapeutic targets, 2021-05, Vol.25 (5), p.347-363

2021

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Procainamide, but not N-Acetylprocainamide, Induces Protein Free Radical Formation on Myeloperoxidase: A Potential Mechanism of Agranulocytosis

Chemical research in toxicology, 2008-05, Vol.21 (5), p.1143-1153

2008

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Prooxidant activity of free radicals derived from phenol-containing neurotransmitters

Toxicology (Amsterdam), 2002-08, Vol.177 (1), p.81-90

2002

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Modulating carbonyl cytotoxicity in intact rat hepatocytes by inhibiting carbonyl-metabolizing enzymes. I. Aliphatic alkenals

Chemico-biological interactions, 2003-02, Vol.143, p.107-117

2003

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Interactions of the antioxidant enzymes NAD(P)H: Quinone oxidoreductase 1 (NQO1) and NRH: Quinone oxidoreductase 2 (NQO2) with pharmacological agents, endogenous biochemicals and environmental contaminants

Isoniazid and host immune system interactions: A proposal for a novel comprehensive mode of action

The Interaction of Myeloperoxidase with the Industrial Contaminant 6‑PPD: A Potential Pathway for Reactive Metabolites

Introduction to the special issue from the 10th meeting of the Canadian Oxidative Stress Consortium

Comparing the oxidative functions of neutrophil myeloperoxidase and cytochrome P450 enzymes in drug metabolism

Caution for the routine use of phenol red – It is more than just a pH indicator

Eosinophil peroxidase oxidizes isoniazid to form the active metabolite against M. tuberculosis, isoniazid-NAD

Scavenging of Free-Radical Metabolites of Aniline Xenobiotics and Drugs by Amino Acid Derivatives: Toxicological Implications of Radical-Transfer Reactions

Current status and future prospects of toxicogenomics in drug discovery

Phenylbutazone Oxidation via Cu,Zn-SOD Peroxidase Activity: An EPR Study

Metabolism of isoniazid by neutrophil myeloperoxidase leads to isoniazid-NAD+ adduct formation: A comparison of the reactivity of isoniazid with its known human metabolites

Proteomic profile of aminoglutethimide-induced apoptosis in HL-60 cells: Role of myeloperoxidase and arylamine free radicals

Anti-inflammatory and antioxidant properties of a novel resveratrol–salicylate hybrid analog

The interaction of diamines and polyamines with the peroxidase-catalyzed metabolism of aromatic amines: a potential mechanism for the modulation of aniline toxicity

Cytoprotective effect of isoniazid against H2O2 derived injury in HL-60 cells

The effect of bicarbonate on menadione-induced redox cycling and cytotoxicity: potential involvement of the carbonate radical

Investigating the Mechanisms of Aromatic Amine-Induced Protein Free Radical Formation by Quantitative Structure−Activity Relationships: Implications for Drug-Induced Agranulocytosis

Molecular cytotoxic mechanisms of anticancer hydroxychalcones

Aminoglutethimide-Induced Protein Free Radical Formation on Myeloperoxidase: A Potential Mechanism of Agranulocytosis

Induction of quinone oxidoreductase 1 enzyme by Rhazya stricta through Nrf2-dependent mechanism

Application of quantitative structure–toxicity relationships for acute NSAID cytotoxicity in rat hepatocytes

Reversing T-cell exhaustion in immunotherapy: a review on current approaches and limitations

Procainamide, but not N-Acetylprocainamide, Induces Protein Free Radical Formation on Myeloperoxidase: A Potential Mechanism of Agranulocytosis

Prooxidant activity of free radicals derived from phenol-containing neurotransmitters

Modulating carbonyl cytotoxicity in intact rat hepatocytes by inhibiting carbonyl-metabolizing enzymes. I. Aliphatic alkenals

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