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The Role of CMC Statisticians: Co‐Practitioners of the Scientific Method

Pharmaceutical statistics : the journal of the pharmaceutical industry, 2024-07

Schofield, Timothy

2024

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Vaccine stability study design and analysis to support product licensure

Biologicals, 2009-11, Vol.37 (6), p.387-396

Schofield, Timothy L.

2009

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Maintenance of vaccine stability through annual stability and comparability studies

Biologicals, 2009-11, Vol.37 (6), p.397-402

Schofield, Timothy L.

2009

Volltextzugriff (PDF)

Basic principles of stability

Biologicals, 2009-11, Vol.37 (6), p.379-386

2009

Volltextzugriff (PDF)

Model format for a vaccine stability report and software solutions

Biologicals, 2009-11, Vol.37 (6), p.417-420

2009

Volltextzugriff (PDF)

Stability evaluation of vaccines

Biologicals, 2009-11, Vol.37 (6), p.355-355

2009

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A vaccine measured with a highly variable assay: Rabies

Biologicals, 2009-11, Vol.37 (6), p.412-415

2009

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Lifecycle Approach to Bioassay

Nonclinical Statistics for Pharmaceutical and Biotechnology Industries, p.433-460

Volltextzugriff (PDF)

Prominent depressor response to endothelin in spontaneously hypertensive rats

European journal of pharmacology, 1989-04, Vol.163 (1), p.199-203

1989

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2′-Nor-2′-deoxyguanosine is an effective therapeutic agent for treatment of experimental herpes keratitis

Antiviral research, 1987-02, Vol.7 (2), p.119-125

1987

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A rational approach for setting and maintaining specifications for biological and biotechnology-derived products Part 2

Biopharm International, 2008-07, Vol.21 (7), p.32

2008

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A Rational Approach for Setting and Maintaining Specifications for Biological and Biotechnology-Derived Products Part 1

Biopharm International, 2008-06, Vol.21 (6), p.42

2008

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A Rational Approach for Setting and Maintaining Specifications for Biological and Biotechnology-Derived Products Part 3

Biopharm International, 2008-08, Vol.21 (8), p.44

2008

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Interaction of Avibactam with Class B Metallo-β-Lactamases

Antimicrobial agents and chemotherapy, 2016-10, Vol.60 (10), p.5655-5662

2016

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Progress in the Development and Application of Small Molecule Inhibitors of Bromodomain–Acetyl-lysine Interactions

Journal of medicinal chemistry, 2012-11, Vol.55 (22), p.9393-9413

2012

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Bicyclic Boronate VNRX-5133 Inhibits Metallo- and Serine-β-Lactamases

Journal of medicinal chemistry, 2019-09, Vol.62 (18), p.8544-8556

2019

Volltextzugriff (PDF)

Reducing Agent‐Mediated Nonenzymatic Conversion of 2‐Oxoglutarate to Succinate: Implications for Oxygenase Assays

Chembiochem : a European journal of chemical biology, 2020-10, Vol.21 (20), p.2898-2902

2020

Volltextzugriff (PDF)

Structural Basis of Metallo-β-Lactamase Inhibition by Captopril Stereoisomers

Antimicrobial agents and chemotherapy, 2016-01, Vol.60 (1), p.142-150

2016

Volltextzugriff (PDF)

Structure‐Activity Studies Reveal Scope for Optimisation of Ebselen‐Type Inhibition of SARS‐CoV‐2 Main Protease

ChemMedChem, 2022-02, Vol.17 (4), p.e202100582-n/a

2022

Volltextzugriff (PDF)

Rhodanine derived enethiols react to give 1,3-dithiolanes and mixed disulfides

RSC medicinal chemistry, 2024-07, Vol.15 (7), p.235-239

2024

Volltextzugriff (PDF)

In vitro efficacy of imipenem-relebactam and cefepime-AAI101 against a global collection of ESBL-positive and carbapenemase-producing Enterobacteriaceae

International journal of antimicrobial agents, 2020-07, Vol.56 (1), p.105925-105925, Article 105925

2020

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Profiling interactions of vaborbactam with metallo-β-lactamases

Bioorganic & medicinal chemistry letters, 2019-08, Vol.29 (15), p.1981-1984

2019

Volltextzugriff (PDF)

Reporter Ligand NMR Screening Method for 2‑Oxoglutarate Oxygenase Inhibitors

Journal of medicinal chemistry, 2013-01, Vol.56 (2), p.547-555

2013

Volltextzugriff (PDF)

Studies on the Substrate Selectivity of the Hypoxia‐Inducible Factor Prolyl Hydroxylase 2 Catalytic Domain

Chembiochem : a European journal of chemical biology, 2018-11, Vol.19 (21), p.2262-2267

2018

Volltextzugriff (PDF)

Faropenem reacts with serine and metallo-β-lactamases to give multiple products

European journal of medicinal chemistry, 2021-04, Vol.215, p.113257-113257, Article 113257

2021

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The Role of CMC Statisticians: Co‐Practitioners of the Scientific Method

Vaccine stability study design and analysis to support product licensure

Maintenance of vaccine stability through annual stability and comparability studies

Basic principles of stability

Model format for a vaccine stability report and software solutions

Stability evaluation of vaccines

A vaccine measured with a highly variable assay: Rabies

Lifecycle Approach to Bioassay

Prominent depressor response to endothelin in spontaneously hypertensive rats

2′-Nor-2′-deoxyguanosine is an effective therapeutic agent for treatment of experimental herpes keratitis

A rational approach for setting and maintaining specifications for biological and biotechnology-derived products Part 2

A Rational Approach for Setting and Maintaining Specifications for Biological and Biotechnology-Derived Products Part 1

A Rational Approach for Setting and Maintaining Specifications for Biological and Biotechnology-Derived Products Part 3

Interaction of Avibactam with Class B Metallo-β-Lactamases

Progress in the Development and Application of Small Molecule Inhibitors of Bromodomain–Acetyl-lysine Interactions

Bicyclic Boronate VNRX-5133 Inhibits Metallo- and Serine-β-Lactamases

Reducing Agent‐Mediated Nonenzymatic Conversion of 2‐Oxoglutarate to Succinate: Implications for Oxygenase Assays

Structural Basis of Metallo-β-Lactamase Inhibition by Captopril Stereoisomers

Structure‐Activity Studies Reveal Scope for Optimisation of Ebselen‐Type Inhibition of SARS‐CoV‐2 Main Protease

Rhodanine derived enethiols react to give 1,3-dithiolanes and mixed disulfides

In vitro efficacy of imipenem-relebactam and cefepime-AAI101 against a global collection of ESBL-positive and carbapenemase-producing Enterobacteriaceae

Profiling interactions of vaborbactam with metallo-β-lactamases

Reporter Ligand NMR Screening Method for 2‑Oxoglutarate Oxygenase Inhibitors

Studies on the Substrate Selectivity of the Hypoxia‐Inducible Factor Prolyl Hydroxylase 2 Catalytic Domain

Faropenem reacts with serine and metallo-β-lactamases to give multiple products

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