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Transporters as Drug Targets in Neurological Diseases

Clinical pharmacology and therapeutics, 2016-11, Vol.100 (5), p.441-453

2016

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Positron emission tomography imaging of tissue P‐glycoprotein activity during pregnancy in the non‐human primate

British journal of pharmacology, 2010-01, Vol.159 (2), p.394-404

2010

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Determination of methamphetamine and amphetamine in abusers' plasma and hair samples with HPLC-FL

Biomedical chromatography, 2003-10, Vol.17 (7), p.471-476

2003

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In Silico Modeling for the Nonlinear Absorption Kinetics of UK-343,664: A P-gp and CYP3A4 Substrate

Molecular pharmaceutics, 2012-03, Vol.9 (3), p.492-504

2012

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Factors influencing regional differences in intestinal absorption of UK-343,664 in rat: Possible role in dose-dependent pharmacokinetics

Journal of pharmaceutical sciences, 2006-02, Vol.95 (2), p.435-445

2006

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Pharmacokinetic interactions between phenylpropanolamine, caffeine and chlorpheniramine in rats

European journal of pharmaceutical sciences, 2004-06, Vol.22 (2), p.209-216

2004

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High performance liquid chromatography with fluorescence detection for the determination of phenylpropanolamine in human plasma and rat’s blood and brain microdialysates using DIB-Cl as a label

Journal of pharmaceutical and biomedical analysis, 2004-02, Vol.34 (3), p.643-650

2004

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HPLC determination of phenylpropanolamine in pharmaceutical OTC preparations

Biomedical chromatography, 2002-10, Vol.16 (7), p.463-469

2002

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Semi-micro column HPLC of triazolam in rat plasma and brain microdialysate and its application to drug interaction study with itraconazole

Journal of pharmaceutical and biomedical analysis, 2003-01, Vol.30 (6), p.1809-1816

2003

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High performance liquid chromatography with UV detection for the simultaneous determination of sympathomimetic amines using 4-(4,5-diphenyl-1H-imidazole-2-yl)benzoyl chloride as a label

Biomedical chromatography, 2001-10, Vol.15 (6), p.379-388

2001

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Development of a Physiologically Based Pharmacokinetic/Pharmacodynamic Model to Predict the Impact of Genetic Polymorphisms on the Pharmacokinetics and Pharmacodynamics Represented by Receptor/Transporter Occupancy of Central Nervous System Drugs

Clinical pharmacokinetics, 2016-08, Vol.55 (8), p.957-969

2016

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Role of ABC Transporters in the Pathogenesis of Alzheimer’s Disease

ACS chemical neuroscience, 2012-11, Vol.3 (11), p.820-831

2012

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Paclitaxel loaded PEG(5000)-DSPE micelles as pulmonary delivery platform: formulation characterization, tissue distribution, plasma pharmacokinetics, and toxicological evaluation

European journal of pharmaceutics and biopharmaceutics, 2011-10, Vol.79 (2), p.276

2011

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Vitamin E Transporters in Cancer Therapy

The AAPS journal, 2015-03, Vol.17 (2), p.313-322

2015

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PEG-lipid micelles as drug carriers: physiochemical attributes, formulation principles and biological implication

Journal of drug targeting, 2015-04, Vol.23 (3), p.222-231

2015

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Physiologically Based Pharmacokinetic/Pharmacodynamic Model for Caffeine Disposition in Pregnancy

Molecular pharmaceutics, 2019-03, Vol.16 (3), p.1340-1349

2019

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Mixed micelles of PEG(2000)-DSPE and vitamin-E TPGS for concurrent delivery of paclitaxel and parthenolide: enhanced chemosenstization and antitumor efficacy against non-small cell lung cancer (NSCLC) cell lines

European journal of pharmaceutical sciences, 2012-05, Vol.46 (1-2), p.64-71

2012

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Development of a physiologically based pharmacokinetic/pharmacodynamic model to identify mechanisms contributing to entacapone low bioavailability

Biopharmaceutics & drug disposition, 2015-12, Vol.36 (9), p.587-602

2015

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Olive-Oil-Derived Oleocanthal Enhances β‑Amyloid Clearance as a Potential Neuroprotective Mechanism against Alzheimer’s Disease: In Vitro and in Vivo Studies

ACS chemical neuroscience, 2013-06, Vol.4 (6), p.973-982

2013

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Orlistat limits cholesterol intestinal absorption by Niemann-pick C1-like 1 (NPC1L1) inhibition

European journal of pharmacology, 2015-09, Vol.762, p.263-269

2015

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Oleocanthal-Rich Extra-Virgin Olive Oil Restores the Blood–Brain Barrier Function through NLRP3 Inflammasome Inhibition Simultaneously with Autophagy Induction in TgSwDI Mice

ACS chemical neuroscience, 2019-08, Vol.10 (8), p.3543-3554

2019

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Editorial: Model-informed drug development and evidence-based translational pharmacology

Frontiers in pharmacology, 2022-12, Vol.13, p.1086551-1086551

2022

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Differences in amyloid-β clearance across mouse and human blood–brain barrier models: Kinetic analysis and mechanistic modeling

Neuropharmacology, 2014-04, Vol.79, p.668-678

2014

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Effect of PEG Surface Conformation on Anticancer Activity and Blood Circulation of Nanoemulsions Loaded with Tocotrienol-Rich Fraction of Palm Oil

The AAPS journal, 2013-10, Vol.15 (4), p.1168-1179

2013

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Oleocanthal Enhances Amyloid‑β Clearance from the Brains of TgSwDI Mice and in Vitro across a Human Blood-Brain Barrier Model

ACS chemical neuroscience, 2015-11, Vol.6 (11), p.1849-1859

2015

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Transporters as Drug Targets in Neurological Diseases

Positron emission tomography imaging of tissue P‐glycoprotein activity during pregnancy in the non‐human primate

Determination of methamphetamine and amphetamine in abusers' plasma and hair samples with HPLC-FL

In Silico Modeling for the Nonlinear Absorption Kinetics of UK-343,664: A P-gp and CYP3A4 Substrate

Factors influencing regional differences in intestinal absorption of UK-343,664 in rat: Possible role in dose-dependent pharmacokinetics

Pharmacokinetic interactions between phenylpropanolamine, caffeine and chlorpheniramine in rats

High performance liquid chromatography with fluorescence detection for the determination of phenylpropanolamine in human plasma and rat’s blood and brain microdialysates using DIB-Cl as a label

HPLC determination of phenylpropanolamine in pharmaceutical OTC preparations

Semi-micro column HPLC of triazolam in rat plasma and brain microdialysate and its application to drug interaction study with itraconazole

High performance liquid chromatography with UV detection for the simultaneous determination of sympathomimetic amines using 4-(4,5-diphenyl-1H-imidazole-2-yl)benzoyl chloride as a label

Development of a Physiologically Based Pharmacokinetic/Pharmacodynamic Model to Predict the Impact of Genetic Polymorphisms on the Pharmacokinetics and Pharmacodynamics Represented by Receptor/Transporter Occupancy of Central Nervous System Drugs

Role of ABC Transporters in the Pathogenesis of Alzheimer’s Disease

Paclitaxel loaded PEG(5000)-DSPE micelles as pulmonary delivery platform: formulation characterization, tissue distribution, plasma pharmacokinetics, and toxicological evaluation

Vitamin E Transporters in Cancer Therapy

PEG-lipid micelles as drug carriers: physiochemical attributes, formulation principles and biological implication

Physiologically Based Pharmacokinetic/Pharmacodynamic Model for Caffeine Disposition in Pregnancy

Mixed micelles of PEG(2000)-DSPE and vitamin-E TPGS for concurrent delivery of paclitaxel and parthenolide: enhanced chemosenstization and antitumor efficacy against non-small cell lung cancer (NSCLC) cell lines

Development of a physiologically based pharmacokinetic/pharmacodynamic model to identify mechanisms contributing to entacapone low bioavailability

Olive-Oil-Derived Oleocanthal Enhances β‑Amyloid Clearance as a Potential Neuroprotective Mechanism against Alzheimer’s Disease: In Vitro and in Vivo Studies

Orlistat limits cholesterol intestinal absorption by Niemann-pick C1-like 1 (NPC1L1) inhibition

Oleocanthal-Rich Extra-Virgin Olive Oil Restores the Blood–Brain Barrier Function through NLRP3 Inflammasome Inhibition Simultaneously with Autophagy Induction in TgSwDI Mice

Editorial: Model-informed drug development and evidence-based translational pharmacology

Differences in amyloid-β clearance across mouse and human blood–brain barrier models: Kinetic analysis and mechanistic modeling

Effect of PEG Surface Conformation on Anticancer Activity and Blood Circulation of Nanoemulsions Loaded with Tocotrienol-Rich Fraction of Palm Oil

Oleocanthal Enhances Amyloid‑β Clearance from the Brains of TgSwDI Mice and in Vitro across a Human Blood-Brain Barrier Model

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