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Design, synthesis and microbiological evaluation of ampicillin-tetramic acid hybrid antibiotics

Journal of antibiotics, 2017-01, Vol.70 (1), p.65-72

2017

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Genetic Mechanisms of Vancomycin Resistance in Clostridioides difficile : A Systematic Review

Antibiotics (Basel), 2022-02, Vol.11 (2), p.258

2022

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Progress in the discovery of treatments for C. difficile infection: A clinical and medicinal chemistry review

Current topics in medicinal chemistry, 2014-01, Vol.14 (1), p.152

2014

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Evaluation of Flavonoid and Resveratrol Chemical Libraries Reveals Abyssinone II as a Promising Antibacterial Lead

ChemMedChem, 2012-09, Vol.7 (9), p.1541-1545

2012

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Chromosomal Resistance to Metronidazole in Clostridioides difficile Can Be Mediated by Epistasis between Iron Homeostasis and Oxidoreductases

Antimicrobial agents and chemotherapy, 2020-07, Vol.64 (8)

2020

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Evaluation of Analogs of Reutericyclin as Prospective Candidates for Treatment of Staphylococcal Skin Infections

Antimicrobial Agents and Chemotherapy, 2009-09, Vol.53 (9), p.4028-4031

2009

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Mode of action and bactericidal properties of surotomycin against growing and nongrowing Clostridium difficile

Antimicrobial agents and chemotherapy, 2015-09, Vol.59 (9), p.5165-5170

2015

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Syntheses and evaluation of macrocyclic engelhardione analogs as antitubercular and antibacterial agents

Journal of antibiotics, 2013-06, Vol.66 (6), p.319-325

2013

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In vivo evaluation of Clostridioides difficile enoyl-ACP reductase II (FabK) inhibition by phenylimidazole unveils a promising narrow-spectrum antimicrobial strategy

Antimicrobial agents and chemotherapy, 2024-03, Vol.68 (3), p.e0122223

2024

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Synthesis and evaluation of phenylimidazole FabK inhibitors as new Anti-C. Difficile agents

Bioorganic & medicinal chemistry, 2023-06, Vol.88-89, p.117330-117330, Article 117330

2023

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Action of nitroheterocyclic drugs against Clostridium difficile

International journal of antimicrobial agents, 2014-10, Vol.44 (4), p.314-319

2014

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Synthesis, Structure–Activity Relationship Studies, and Antibacterial Evaluation of 4‑Chromanones and Chalcones, as Well as Olympicin A and Derivatives

Journal of medicinal chemistry, 2014-10, Vol.57 (20), p.8398-8420

2014

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Rifamycin Resistance in Clostridium difficile Is Generally Associated with a Low Fitness Burden

Antimicrobial agents and chemotherapy, 2016-09, Vol.60 (9), p.5604-5607

2016

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New β-lactam – Tetramic acid hybrids show promising antibacterial activities

Bioorganic & medicinal chemistry letters, 2018-10, Vol.28 (18), p.3105-3112

2018

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Novel Acyl Phosphate Mimics that Target PlsY, an Essential Acyltransferase in Gram-Positive Bacteria

ChemMedChem, 2008-12, Vol.3 (12), p.1936-1945

2008

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The structure–activity relationship of urea derivatives as anti-tuberculosis agents

Bioorganic & medicinal chemistry, 2011-09, Vol.19 (18), p.5585-5595

2011

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Gastrointestinal localization of metronidazole by a lactobacilli-inspired tetramic acid motif improves treatment outcomes in the hamster model of Clostridium difficile infection

Journal of antimicrobial chemotherapy, 2015-11, Vol.70 (11), p.3061-3069

2015

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Evaluation of Fusobacterium nucleatum Enoyl-ACP Reductase (FabK) as a Narrow-Spectrum Drug Target

ACS infectious diseases, 2024-05, Vol.10 (5), p.1612-1623

2024

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The membrane as a target for controlling hypervirulent Clostridium difficile infections

Journal of antimicrobial chemotherapy, 2013-04, Vol.68 (4), p.806-815

2013

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Solid-Phase Synthesis and Antibacterial Activity of Cyclohexapeptide Wollamide B Analogs

ACS combinatorial science, 2018-03, Vol.20 (3), p.172-185

2018

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Structural Studies of Pterin-Based Inhibitors of Dihydropteroate Synthase

Journal of medicinal chemistry, 2010-01, Vol.53 (1), p.166-177

2010

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A microbiological assessment of novel nitrofuranylamides as anti-tuberculosis agents

Journal of antimicrobial chemotherapy, 2008-11, Vol.62 (5), p.1037-1045

2008

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Reutericyclin and related analogues kill stationary phase Clostridium difficile at achievable colonic concentrations

Journal of antimicrobial chemotherapy, 2011-08, Vol.66 (8), p.1773-1776

2011

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The Fatty Acid Synthesis Protein Enoyl-ACP Reductase II (FabK) is a Target for Narrow-Spectrum Antibacterials for Clostridium difficile Infection

ACS infectious diseases, 2019-02, Vol.5 (2), p.208-217

2019

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In vivo transfer of high-level mupirocin resistance from Staphylococcus epidermidis to methicillin-resistant Staphylococcus aureus associated with failure of mupirocin prophylaxis

Journal of antimicrobial chemotherapy, 2005-12, Vol.56 (6), p.1166-1168

2005

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Design, synthesis and microbiological evaluation of ampicillin-tetramic acid hybrid antibiotics

Genetic Mechanisms of Vancomycin Resistance in Clostridioides difficile : A Systematic Review

Progress in the discovery of treatments for C. difficile infection: A clinical and medicinal chemistry review

Evaluation of Flavonoid and Resveratrol Chemical Libraries Reveals Abyssinone II as a Promising Antibacterial Lead

Chromosomal Resistance to Metronidazole in Clostridioides difficile Can Be Mediated by Epistasis between Iron Homeostasis and Oxidoreductases

Evaluation of Analogs of Reutericyclin as Prospective Candidates for Treatment of Staphylococcal Skin Infections

Mode of action and bactericidal properties of surotomycin against growing and nongrowing Clostridium difficile

Syntheses and evaluation of macrocyclic engelhardione analogs as antitubercular and antibacterial agents

In vivo evaluation of Clostridioides difficile enoyl-ACP reductase II (FabK) inhibition by phenylimidazole unveils a promising narrow-spectrum antimicrobial strategy

Synthesis and evaluation of phenylimidazole FabK inhibitors as new Anti-C. Difficile agents

Action of nitroheterocyclic drugs against Clostridium difficile

Synthesis, Structure–Activity Relationship Studies, and Antibacterial Evaluation of 4‑Chromanones and Chalcones, as Well as Olympicin A and Derivatives

Rifamycin Resistance in Clostridium difficile Is Generally Associated with a Low Fitness Burden

New β-lactam – Tetramic acid hybrids show promising antibacterial activities

Novel Acyl Phosphate Mimics that Target PlsY, an Essential Acyltransferase in Gram-Positive Bacteria

The structure–activity relationship of urea derivatives as anti-tuberculosis agents

Gastrointestinal localization of metronidazole by a lactobacilli-inspired tetramic acid motif improves treatment outcomes in the hamster model of Clostridium difficile infection

Evaluation of Fusobacterium nucleatum Enoyl-ACP Reductase (FabK) as a Narrow-Spectrum Drug Target

The membrane as a target for controlling hypervirulent Clostridium difficile infections

Solid-Phase Synthesis and Antibacterial Activity of Cyclohexapeptide Wollamide B Analogs

Structural Studies of Pterin-Based Inhibitors of Dihydropteroate Synthase

A microbiological assessment of novel nitrofuranylamides as anti-tuberculosis agents

Reutericyclin and related analogues kill stationary phase Clostridium difficile at achievable colonic concentrations

The Fatty Acid Synthesis Protein Enoyl-ACP Reductase II (FabK) is a Target for Narrow-Spectrum Antibacterials for Clostridium difficile Infection

In vivo transfer of high-level mupirocin resistance from Staphylococcus epidermidis to methicillin-resistant Staphylococcus aureus associated with failure of mupirocin prophylaxis

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