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Evaluation of clinical outcomes and efficacy of palonosetron and granisetron in combination with dexamethasone in Egyptian patients receiving highly emetogenic chemotherapy

Cancer chemotherapy and pharmacology, 2021-07, Vol.88 (1), p.121-129

2021

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The Effectiveness of 3 Combined Therapeutic Regimens in Egyptian Patients with Moderate-to-Severe Chronic Obstructive Pulmonary Disease: A Randomized Double-Blind Prospective Pilot Study

Current therapeutic research, 2021-01, Vol.94, p.100625, Article 100625

2021

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Mebendazole; from an anti-parasitic drug to a promising candidate for drug repurposing in colorectal cancer

Life sciences (1973), 2022-06, Vol.299, p.120536-120536, Article 120536

2022

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Structural alterations based on naproxen scaffold: Synthesis, evaluation of antitumor activity and COX-2 inhibition, and molecular docking

European journal of medicinal chemistry, 2018-10, Vol.158, p.134-143

2018

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Effect of bone marrow mesenchymal stem cells-derived exosomes on diabetes-induced retinal injury: Implication of Wnt/ b-catenin signaling pathway

Biomedicine & pharmacotherapy, 2022-10, Vol.154, p.113554-113554, Article 113554

2022

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Neuroprotective mechanisms of sildenafil and selenium in PTZ-kindling model: Implications in epilepsy

European journal of pharmacology, 2018-08, Vol.833, p.131-144

2018

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Inhibition of thioredoxin-interacting protein and inflammasome assembly using verapamil mitigates diabetic retinopathy and pancreatic injury

European journal of pharmacology, 2021-06, Vol.901, p.174061, Article 174061

2021

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A novel role of Nano selenium and sildenafil on streptozotocin-induced diabetic nephropathy in rats by modulation of inflammatory, oxidative, and apoptotic pathways

Life sciences (1973), 2022-08, Vol.303, p.120691-120691, Article 120691

2022

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Pirfenidone and vitamin D mitigate renal fibrosis induced by doxorubicin in mice with Ehrlich solid tumor

Life sciences (1973), 2022-01, Vol.288, p.120185, Article 120185

2022

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Structure-based design of phthalimide derivatives as potential cyclooxygenase-2 (COX-2) inhibitors: Anti-inflammatory and analgesic activities

European journal of medicinal chemistry, 2015-03, Vol.92, p.115-123

2015

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Pirfenidone and Vitamin D Ameliorate Cardiac Fibrosis Induced by Doxorubicin in Ehrlich Ascites Carcinoma Bearing Mice: Modulation of Monocyte Chemoattractant Protein-1 and Jun N-terminal Kinase-1 Pathways

Pharmaceuticals (Basel, Switzerland), 2020-10, Vol.13 (11), p.348

2020

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Design, synthesis, and biological evaluation of substituted hydrazone and pyrazole derivatives as selective COX-2 inhibitors: Molecular docking study

Bioorganic & medicinal chemistry, 2011-06, Vol.19 (11), p.3416-3424

2011

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Design and synthesis of novel 7-aminoquinazoline derivatives: Antitumor and anticonvulsant activities

Bioorganic & medicinal chemistry letters, 2012-03, Vol.22 (5), p.1879-1885

2012

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Design, synthesis and biological evaluation of 2-mercapto-3-phenethylquinazoline bearing anilide fragments as potential antitumor agents: Molecular docking study

Bioorganic & medicinal chemistry letters, 2013-07, Vol.23 (13), p.3935-3941

2013

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Synthesis and biological evaluation of 2-styrylquinolines as antitumour agents and EGFR kinase inhibitors: molecular docking study

Journal of enzyme inhibition and medicinal chemistry, 2018-01, Vol.33 (1), p.199-209

2018

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Synthesis and antitumor evaluation of trimethoxyanilides based on 4(3H)-quinazolinone scaffolds

European journal of medicinal chemistry, 2016-04, Vol.112, p.106-113

2016

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Design, synthesis of 2,3-disubstitued 4(3H)-quinazolinone derivatives as anti-inflammatory and analgesic agents: COX-1/2 inhibitory activities and molecular docking studies

Bioorganic & medicinal chemistry, 2016-08, Vol.24 (16), p.3818-3828

2016

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Synthesis, potential antitumor activity, cell cycle analysis, and multitarget mechanisms of novel hydrazones incorporating a 4-methylsulfonylbenzene scaffold: a molecular docking study

Journal of enzyme inhibition and medicinal chemistry, 2021-01, Vol.36 (1), p.1520-1538

2021

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Synthesis, anti-inflammatory, analgesic, COX-1/2 inhibitory activities and molecular docking studies of substituted 2-mercapto-4(3H)-quinazolinones

European journal of medicinal chemistry, 2016-10, Vol.121, p.410-421

2016

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Design, synthesis and biological evaluation of some novel substituted quinazolines as antitumor agents

European journal of medicinal chemistry, 2014-05, Vol.79, p.446-454

2014

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Novel N -bridged pyrazole-1-carbothioamides with potential antiproliferative activity: design, synthesis, in vitro and in silico studies

Future medicinal chemistry, 2021-10, Vol.13 (20), p.1743-1766

2021

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S-substituted 2-mercaptoquinazolin-4(3H)-one and 4-ethylbenzensulfonamides act as potent and selective human carbonic anhydrase IX and XII inhibitors

Journal of enzyme inhibition and medicinal chemistry, 2020-01, Vol.35 (1), p.733-743

2020

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Enhanced Antioxidant and Cytotoxic Potentials of Lipopolysaccharides-Injected Musca domestica Larvae

Pharmaceutics, 2020-11, Vol.12 (11), p.1111

2020

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Deletion of thioredoxin‐interacting protein preserves retinal neuronal function by preventing inflammation and vascular injury

British journal of pharmacology, 2014-03, Vol.171 (5), p.1299-1313

2014

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Design, synthesis, and carbonic anhydrase inhibition activities of Schiff bases incorporating benzenesulfonamide scaffold: Molecular docking application

Saudi pharmaceutical journal, 2023-12, Vol.31 (12), p.101866-101866, Article 101866

2023

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Evaluation of clinical outcomes and efficacy of palonosetron and granisetron in combination with dexamethasone in Egyptian patients receiving highly emetogenic chemotherapy

The Effectiveness of 3 Combined Therapeutic Regimens in Egyptian Patients with Moderate-to-Severe Chronic Obstructive Pulmonary Disease: A Randomized Double-Blind Prospective Pilot Study

Mebendazole; from an anti-parasitic drug to a promising candidate for drug repurposing in colorectal cancer

Structural alterations based on naproxen scaffold: Synthesis, evaluation of antitumor activity and COX-2 inhibition, and molecular docking

Effect of bone marrow mesenchymal stem cells-derived exosomes on diabetes-induced retinal injury: Implication of Wnt/ b-catenin signaling pathway

Neuroprotective mechanisms of sildenafil and selenium in PTZ-kindling model: Implications in epilepsy

Inhibition of thioredoxin-interacting protein and inflammasome assembly using verapamil mitigates diabetic retinopathy and pancreatic injury

A novel role of Nano selenium and sildenafil on streptozotocin-induced diabetic nephropathy in rats by modulation of inflammatory, oxidative, and apoptotic pathways

Pirfenidone and vitamin D mitigate renal fibrosis induced by doxorubicin in mice with Ehrlich solid tumor

Structure-based design of phthalimide derivatives as potential cyclooxygenase-2 (COX-2) inhibitors: Anti-inflammatory and analgesic activities

Pirfenidone and Vitamin D Ameliorate Cardiac Fibrosis Induced by Doxorubicin in Ehrlich Ascites Carcinoma Bearing Mice: Modulation of Monocyte Chemoattractant Protein-1 and Jun N-terminal Kinase-1 Pathways

Design, synthesis, and biological evaluation of substituted hydrazone and pyrazole derivatives as selective COX-2 inhibitors: Molecular docking study

Design and synthesis of novel 7-aminoquinazoline derivatives: Antitumor and anticonvulsant activities

Design, synthesis and biological evaluation of 2-mercapto-3-phenethylquinazoline bearing anilide fragments as potential antitumor agents: Molecular docking study

Synthesis and biological evaluation of 2-styrylquinolines as antitumour agents and EGFR kinase inhibitors: molecular docking study

Synthesis and antitumor evaluation of trimethoxyanilides based on 4(3H)-quinazolinone scaffolds

Design, synthesis of 2,3-disubstitued 4(3H)-quinazolinone derivatives as anti-inflammatory and analgesic agents: COX-1/2 inhibitory activities and molecular docking studies

Synthesis, potential antitumor activity, cell cycle analysis, and multitarget mechanisms of novel hydrazones incorporating a 4-methylsulfonylbenzene scaffold: a molecular docking study

Synthesis, anti-inflammatory, analgesic, COX-1/2 inhibitory activities and molecular docking studies of substituted 2-mercapto-4(3H)-quinazolinones

Design, synthesis and biological evaluation of some novel substituted quinazolines as antitumor agents

Novel N -bridged pyrazole-1-carbothioamides with potential antiproliferative activity: design, synthesis, in vitro and in silico studies

S-substituted 2-mercaptoquinazolin-4(3H)-one and 4-ethylbenzensulfonamides act as potent and selective human carbonic anhydrase IX and XII inhibitors

Enhanced Antioxidant and Cytotoxic Potentials of Lipopolysaccharides-Injected Musca domestica Larvae

Deletion of thioredoxin‐interacting protein preserves retinal neuronal function by preventing inflammation and vascular injury

Design, synthesis, and carbonic anhydrase inhibition activities of Schiff bases incorporating benzenesulfonamide scaffold: Molecular docking application

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