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In Vitro and In Vivo Studies of the Trypanocidal Effect of Novel Quinolines

Antimicrobial agents and chemotherapy, 2018-02, Vol.62 (2)

2018

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Phenotypic Screening In Vitro of Novel Aromatic Amidines against Trypanosoma cruzi

Antimicrobial agents and chemotherapy, 2016-08, Vol.60 (8), p.4701-4707

2016

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Synthesis of some new 2-substituted-phenyl-1H-benzimidazole-5-carbonitriles and their potent activity against Candida species

Bioorganic & medicinal chemistry, 2002-08, Vol.10 (8), p.2589-2596

2002

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Antileishmanial Efficacy and Pharmacokinetics of DB766-Azole Combinations

Antimicrobial agents and chemotherapy, 2018-01, Vol.62 (1)

2018

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The Trypanocidal Activity of Amidine Compounds Does Not Correlate with Their Binding Affinity to Trypanosoma cruzi Kinetoplast DNA

Antimicrobial Agents and Chemotherapy, 2011-10, Vol.55 (10), p.4765-4773

2011

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Extended Aromatic Furan Amidino Derivatives as Anti-Pneumocystis carinii Agents

Journal of medicinal chemistry, 1998-09, Vol.41 (20), p.3872-3878

1998

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In Vitro and In Vivo Studies of the Biological Activity of Novel Arylimidamides against Trypanosoma cruzi

Antimicrobial agents and chemotherapy, 2014-07, Vol.58 (7), p.4191-4195

2014

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Cellular Effects of Reversed Amidines on Trypanosoma cruzi

Antimicrobial Agents and Chemotherapy, 2007-11, Vol.51 (11), p.3803-3809

2007

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Phenyl substitution of furamidine markedly potentiates its anti-parasitic activity against Trypanosoma cruzi and Leishmania amazonensis

Biochemical pharmacology, 2004-08, Vol.68 (4), p.593-600

2004

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Restoring and Enhancing the Potency of Existing Antibiotics against Drug-Resistant Gram-Negative Bacteria through the Development of Potent Small-Molecule Adjuvants

ACS infectious diseases, 2022-08, Vol.8 (8), p.1491-1508

2022

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In Vitro and In Vivo Studies of the Trypanocidal Activity of a Diarylthiophene Diamidine against Trypanosoma cruzi

Antimicrobial Agents and Chemotherapy, 2008-09, Vol.52 (9), p.3307-3314

2008

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Aromatic diamidines as antiparasitic agents

Expert opinion on investigational drugs, 2005-08, Vol.14 (8), p.957-972

2005

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Synthesis, DNA Affinity, and Antiprotozoal Activity of Fused Ring Dicationic Compounds and Their Prodrugs

Journal of medicinal chemistry, 2005-08, Vol.48 (17), p.5480-5488

2005

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CYP4F enzymes are the major enzymes in human liver microsomes that catalyze the O-demethylation of the antiparasitic prodrug DB289 [2,5-bis(4-amidinophenyl)furan-bis-O-methylamidoxime]

Drug metabolism and disposition, 2006-12, Vol.34 (12), p.1985-1994

2006

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Evaluation of Arylimidamides DB1955 and DB1960 as Candidates against Visceral Leishmaniasis and Chagas' Disease: In Vivo Efficacy, Acute Toxicity, Pharmacokinetics, and Toxicology Studies

Antimicrobial Agents and Chemotherapy, 2012-07, Vol.56 (7), p.3690-3699

2012

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Detection of Inhibition of Bovine Viral Diarrhea Virus by Aromatic Cationic Molecules

Antimicrobial Agents and Chemotherapy, 2003-07, Vol.47 (7), p.2223-2230

2003

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In Vitro Antifungal Activities of a Series of Dication-Substituted Carbazoles, Furans, and Benzimidazoles

Antimicrobial Agents and Chemotherapy, 1998-10, Vol.42 (10), p.2503-2510

1998

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2,4-Diphenyl Furan Diamidines as Novel Anti-Pneumocystis carinii Pneumonia Agents

Journal of medicinal chemistry, 1999-06, Vol.42 (12), p.2260-2265

1999

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Structure-In Vitro Activity Relationships of Pentamidine Analogues and Dication-Substituted Bis-Benzimidazoles as New Antifungal Agents

Antimicrobial Agents and Chemotherapy, 1998-10, Vol.42 (10), p.2495-2502

1998

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Prodrugs for Amidines: Synthesis and Anti-Pneumocystis carinii Activity of Carbamates of 2,5-Bis(4-amidinophenyl)furan

Journal of medicinal chemistry, 1999-09, Vol.42 (19), p.3994-4000

1999

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Phenotypic evaluation and in silico ADMET properties of novel arylimidamides in acute mouse models of Trypanosoma cruzi infection

Drug design, development and therapy, 2017-01, Vol.11, p.1095-1105

2017

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2,5-Bis[4-(N-alkylamidino)phenyl]furans as Anti-Pneumocystis carinii Agents

Journal of medicinal chemistry, 1998-01, Vol.41 (1), p.124-129

1998

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The activity of diguanidino and ‘reversed’ diamidino 2,5-diarylfurans versus Trypanosoma cruzi and Leishmania donovani

Bioorganic & medicinal chemistry letters, 2003-06, Vol.13 (12), p.2065-2069

2003

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Distribution of Furamidine Analogues in Tumor Cells: Influence of the Number of Positive Charges

Journal of medicinal chemistry, 2002-05, Vol.45 (10), p.1994-2002

2002

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Prevention and elimination of bovine viral diarrhea virus infections in fetal fibroblast cells

Antiviral research, 2004-11, Vol.64 (2), p.113-118

2004

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In Vitro and In Vivo Studies of the Trypanocidal Effect of Novel Quinolines

Phenotypic Screening In Vitro of Novel Aromatic Amidines against Trypanosoma cruzi

Synthesis of some new 2-substituted-phenyl-1H-benzimidazole-5-carbonitriles and their potent activity against Candida species

Antileishmanial Efficacy and Pharmacokinetics of DB766-Azole Combinations

The Trypanocidal Activity of Amidine Compounds Does Not Correlate with Their Binding Affinity to Trypanosoma cruzi Kinetoplast DNA

Extended Aromatic Furan Amidino Derivatives as Anti-Pneumocystis carinii Agents

In Vitro and In Vivo Studies of the Biological Activity of Novel Arylimidamides against Trypanosoma cruzi

Cellular Effects of Reversed Amidines on Trypanosoma cruzi

Phenyl substitution of furamidine markedly potentiates its anti-parasitic activity against Trypanosoma cruzi and Leishmania amazonensis

Restoring and Enhancing the Potency of Existing Antibiotics against Drug-Resistant Gram-Negative Bacteria through the Development of Potent Small-Molecule Adjuvants

In Vitro and In Vivo Studies of the Trypanocidal Activity of a Diarylthiophene Diamidine against Trypanosoma cruzi

Aromatic diamidines as antiparasitic agents

Synthesis, DNA Affinity, and Antiprotozoal Activity of Fused Ring Dicationic Compounds and Their Prodrugs

CYP4F enzymes are the major enzymes in human liver microsomes that catalyze the O-demethylation of the antiparasitic prodrug DB289 [2,5-bis(4-amidinophenyl)furan-bis-O-methylamidoxime]

Evaluation of Arylimidamides DB1955 and DB1960 as Candidates against Visceral Leishmaniasis and Chagas' Disease: In Vivo Efficacy, Acute Toxicity, Pharmacokinetics, and Toxicology Studies

Detection of Inhibition of Bovine Viral Diarrhea Virus by Aromatic Cationic Molecules

In Vitro Antifungal Activities of a Series of Dication-Substituted Carbazoles, Furans, and Benzimidazoles

2,4-Diphenyl Furan Diamidines as Novel Anti-Pneumocystis carinii Pneumonia Agents

Structure-In Vitro Activity Relationships of Pentamidine Analogues and Dication-Substituted Bis-Benzimidazoles as New Antifungal Agents

Prodrugs for Amidines: Synthesis and Anti-Pneumocystis carinii Activity of Carbamates of 2,5-Bis(4-amidinophenyl)furan

Phenotypic evaluation and in silico ADMET properties of novel arylimidamides in acute mouse models of Trypanosoma cruzi infection

2,5-Bis[4-(N-alkylamidino)phenyl]furans as Anti-Pneumocystis carinii Agents

The activity of diguanidino and ‘reversed’ diamidino 2,5-diarylfurans versus Trypanosoma cruzi and Leishmania donovani

Distribution of Furamidine Analogues in Tumor Cells: Influence of the Number of Positive Charges

Prevention and elimination of bovine viral diarrhea virus infections in fetal fibroblast cells

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