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The epidermis of the pupae of Tenebrio molitor L. as target organ for the juvenile hormone analogue 10,11-epoxy-6,7-trans-2,3-trans-farnesylpropenylether (author's transl)

Zeitschrift für Naturforschung. Teil C. Biochemie, Biophysik, Biologie, Virologie, 1973-03, Vol.28 (3), p.173

1973

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Identification of bicyclic hexafluoroisopropyl alcohol sulfonamides as retinoic acid receptor-related orphan receptor gamma (RORγ/RORc) inverse agonists. Employing structure-based drug design to improve pregnane X receptor (PXR) selectivity

Bioorganic & medicinal chemistry letters, 2018-01, Vol.28 (2), p.85-93

2018

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Antitumor activity of poly(ethylene glycol)–camptothecin conjugate: The inhibition of tumor growth in vivo

Journal of controlled release, 2005-12, Vol.110 (1), p.90-102

2005

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Dual Inhibition of Interleukin-23 and Interleukin-17 Offers Superior Efficacy in Mouse Models of Autoimmunity

The Journal of pharmacology and experimental therapeutics, 2015-08, Vol.354 (2), p.152

2015

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Identification and Preclinical Pharmacology of ((1R,3S)‑1-Amino-3-((S)‑6-(2-methoxyphenethyl)-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopentyl)methanol (BMS-986166): A Differentiated Sphingosine-1-phosphate Receptor 1 (S1P1) Modulator Advanced into Clinical Trials

Journal of medicinal chemistry, 2019-03, Vol.62 (5), p.2265-2285

2019

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Structure-based Discovery of Phenyl (3-Phenylpyrrolidin-3-yl)sulfones as Selective, Orally Active RORγt Inverse Agonists

ACS medicinal chemistry letters, 2019-03, Vol.10 (3), p.367-373

2019

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Discovery of BMS-986251: A Clinically Viable, Potent, and Selective RORγt Inverse Agonist

ACS medicinal chemistry letters, 2020-06, Vol.11 (6), p.1221-1227

2020

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NS3 Peptide, a Novel Potent Hepatitis C Virus NS3 Helicase Inhibitor: Its Mechanism of Action and Antiviral Activity in the Replicon System

Antimicrobial Agents and Chemotherapy, 2008-02, Vol.52 (2), p.393-401

2008

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A Novel Method to Estimate Long‐Term Chronological Changes From Fragmented Observations in Disease Progression

Clinical pharmacology and therapeutics, 2019-02, Vol.105 (2), p.436-447

2019

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Receptors for NPY and PACAP differ in expression and activity during adipogenesis in the murine 3T3‐L1 fibroblast cell line

British journal of pharmacology, 2009-06, Vol.157 (4), p.620-632

2009

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Synthesis and biological evaluation of 2,7-dihydro-3H-dibenzo[de,h]cinnoline-3,7-dione derivatives, a novel group of anticancer agents active on a multidrug resistant cell line

Bioorganic & medicinal chemistry, 2003-02, Vol.11 (4), p.561-572

2003

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Ring-Expanded (“Fat”) Nucleoside and Nucleotide Analogues Exhibit Potent in Vitro Activity against Flaviviridae NTPases/Helicases, Including Those of the West Nile Virus, Hepatitis C Virus, and Japanese Encephalitis Virus

Journal of medicinal chemistry, 2003-09, Vol.46 (19), p.4149-4164

2003

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Characterization of Imidazo[4,5-d]Pyridazine Nucleosides as Modulators of Unwinding Reaction Mediated by West Nile Virus Nucleoside Triphosphatase/Helicase: Evidence for Activity on the Level of Substrate and/or Enzyme

Antimicrobial Agents and Chemotherapy, 2002-05, Vol.46 (5), p.1231-1239

2002

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Cellular and in Vivo Activity of JNJ-28871063, A Nonquinazoline Pan-ErbB Kinase Inhibitor That Crosses the Blood-Brain Barrier and Displays Efficacy against Intracranial Tumors

Molecular pharmacology, 2008-02, Vol.73 (2), p.338-348

2008

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The Mechanism of Overcoming Multidrug Resistance (MDR) of Fungi by Amphotericin B and Its Derivatives

Journal of antibiotics, 2007-07, Vol.60 (7), p.436-446

2007

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Studies of the Effects of Antifungal Cationic Derivatives of Amphotericin B on Human Erythrocytes

The Journal of Antibiotics, 2004/10/25, Vol.57(10), pp.669-678

2004

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Potent Inhibition of NTPase/Helicase of the West Nile Virus by Ring-Expanded (“Fat”) Nucleoside Analogues

Journal of medicinal chemistry, 2003-10, Vol.46 (22), p.4776-4789

2003

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Synthesis of 7-oxo-7H-naphtho[1,2,3-de]quinoline derivatives as potential anticancer agents active on multidrug resistant cell lines

Bioorganic & medicinal chemistry, 2006-05, Vol.14 (9), p.2880-2886

2006

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2,7-Dihydro-3H-pyridazino[5,4,3-kl]acridin-3-one derivatives, novel type of cytotoxic agents active on multidrug-resistant cell lines. Synthesis and biological evaluation

Bioorganic & medicinal chemistry, 2005-03, Vol.13 (6), p.1969

2005

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Application of real-time PCR for testing antiviral compounds against Lassa virus, SARS coronavirus and Ebola virus in vitro

Antiviral research, 2004-09, Vol.63 (3), p.209-215

2004

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Effect of Modification of 6-[(Aminoalkyl)amino]-7H-benzo[e]-perimidin-7-ones on Their Cytotoxic Activity Toward Sensitive and Multidrug Resistant Tumor Cell Lines. Synthesis and Biological Evaluation

Bioorganic & medicinal chemistry, 2002-04, Vol.10 (4), p.1025-1035

2002

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Unique Technology for Solubilization and Delivery of Highly Lipophilic Bioactive Molecules

Journal of drug targeting, 2004-01, Vol.12 (7), p.415-424

2004

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8,11-Dihydroxy-6-[(aminoalkyl)amino]-7H-benzo[e]perimidin-7-ones with Activity in Multidrug-Resistant Cell Lines: Synthesis and Antitumor Evaluation

Journal of medicinal chemistry, 1999-09, Vol.42 (18), p.3494-3501

1999

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Evaluation of lipid-lowering therapies at an ethnically diverse clinic

American journal of health-system pharmacy, 2003-06, Vol.60 (12), p.1282-1283

2003

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Synthesis of (Dialkylamino)alkyl-Disubstituted Pyrimido[5,6,1-de]acridines, a Novel Group of Anticancer Agents Active on a Multidrug Resistant Cell Line

Journal of medicinal chemistry, 1995-08, Vol.38 (17), p.3282-3286

1995

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The epidermis of the pupae of Tenebrio molitor L. as target organ for the juvenile hormone analogue 10,11-epoxy-6,7-trans-2,3-trans-farnesylpropenylether (author's transl)

Identification of bicyclic hexafluoroisopropyl alcohol sulfonamides as retinoic acid receptor-related orphan receptor gamma (RORγ/RORc) inverse agonists. Employing structure-based drug design to improve pregnane X receptor (PXR) selectivity

Antitumor activity of poly(ethylene glycol)–camptothecin conjugate: The inhibition of tumor growth in vivo

Dual Inhibition of Interleukin-23 and Interleukin-17 Offers Superior Efficacy in Mouse Models of Autoimmunity

Identification and Preclinical Pharmacology of ((1R,3S)‑1-Amino-3-((S)‑6-(2-methoxyphenethyl)-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopentyl)methanol (BMS-986166): A Differentiated Sphingosine-1-phosphate Receptor 1 (S1P1) Modulator Advanced into Clinical Trials

Structure-based Discovery of Phenyl (3-Phenylpyrrolidin-3-yl)sulfones as Selective, Orally Active RORγt Inverse Agonists

Discovery of BMS-986251: A Clinically Viable, Potent, and Selective RORγt Inverse Agonist

NS3 Peptide, a Novel Potent Hepatitis C Virus NS3 Helicase Inhibitor: Its Mechanism of Action and Antiviral Activity in the Replicon System

A Novel Method to Estimate Long‐Term Chronological Changes From Fragmented Observations in Disease Progression

Receptors for NPY and PACAP differ in expression and activity during adipogenesis in the murine 3T3‐L1 fibroblast cell line

Synthesis and biological evaluation of 2,7-dihydro-3H-dibenzo[de,h]cinnoline-3,7-dione derivatives, a novel group of anticancer agents active on a multidrug resistant cell line

Ring-Expanded (“Fat”) Nucleoside and Nucleotide Analogues Exhibit Potent in Vitro Activity against Flaviviridae NTPases/Helicases, Including Those of the West Nile Virus, Hepatitis C Virus, and Japanese Encephalitis Virus

Characterization of Imidazo[4,5-d]Pyridazine Nucleosides as Modulators of Unwinding Reaction Mediated by West Nile Virus Nucleoside Triphosphatase/Helicase: Evidence for Activity on the Level of Substrate and/or Enzyme

Cellular and in Vivo Activity of JNJ-28871063, A Nonquinazoline Pan-ErbB Kinase Inhibitor That Crosses the Blood-Brain Barrier and Displays Efficacy against Intracranial Tumors

The Mechanism of Overcoming Multidrug Resistance (MDR) of Fungi by Amphotericin B and Its Derivatives

Studies of the Effects of Antifungal Cationic Derivatives of Amphotericin B on Human Erythrocytes

Potent Inhibition of NTPase/Helicase of the West Nile Virus by Ring-Expanded (“Fat”) Nucleoside Analogues

Synthesis of 7-oxo-7H-naphtho[1,2,3-de]quinoline derivatives as potential anticancer agents active on multidrug resistant cell lines

2,7-Dihydro-3H-pyridazino[5,4,3-kl]acridin-3-one derivatives, novel type of cytotoxic agents active on multidrug-resistant cell lines. Synthesis and biological evaluation

Application of real-time PCR for testing antiviral compounds against Lassa virus, SARS coronavirus and Ebola virus in vitro

Effect of Modification of 6-[(Aminoalkyl)amino]-7H-benzo[e]-perimidin-7-ones on Their Cytotoxic Activity Toward Sensitive and Multidrug Resistant Tumor Cell Lines. Synthesis and Biological Evaluation

Unique Technology for Solubilization and Delivery of Highly Lipophilic Bioactive Molecules

8,11-Dihydroxy-6-[(aminoalkyl)amino]-7H-benzo[e]perimidin-7-ones with Activity in Multidrug-Resistant Cell Lines: Synthesis and Antitumor Evaluation

Evaluation of lipid-lowering therapies at an ethnically diverse clinic

Synthesis of (Dialkylamino)alkyl-Disubstituted Pyrimido[5,6,1-de]acridines, a Novel Group of Anticancer Agents Active on a Multidrug Resistant Cell Line

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