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Phase I study of single agent NIZ985, a recombinant heterodimeric IL-15 agonist, in adult patients with metastatic or unresectable solid tumors

Journal for immunotherapy of cancer, 2021-11, Vol.9 (11), p.e003388

2021

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Systemic immune changes accompany combination treatment with immunotoxin LMB‐100 and nab‐paclitaxel

Cancer medicine (Malden, MA), 2023-02, Vol.12 (4), p.4236-4249

2023

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Development and utilization of a combined LC–UV and LC–MS/MS method for the simultaneous analysis of tegafur and 5-fluorouracil in human plasma to support a phase I clinical study of oral UFT®/leucovorin

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2012-06, Vol.898, p.32-37

2012

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PARP inhibitors: A review of the pharmacology, pharmacokinetics, and pharmacogenetics

Seminars in oncology, 2024-02, Vol.51 (1-2), p.19-24

2024

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Pharmacokinetic Simulation Analysis of Less Frequent Nivolumab and Pembrolizumab Dosing: Pharmacoeconomic Rationale for Dose Deescalation

Journal of clinical pharmacology, 2022-04, Vol.62 (4), p.532-540

2022

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Phase I and Preliminary Phase II Study of TRC105 in Combination with Sorafenib in Hepatocellular Carcinoma

Clinical cancer research, 2017-08, Vol.23 (16), p.4633-4641

2017

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HSD3B1(1245A>C) variant regulates dueling abiraterone metabolite effects in prostate cancer

The Journal of clinical investigation, 2018-08, Vol.128 (8), p.3333-3340

2018

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Alcohol and Aldehyde Dehydrogenases Contribute to Sex-Related Differences in Clearance of Zolpidem in Rats

Frontiers in pharmacology, 2016-08, Vol.7, p.260-260

2016

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A phase I/II trial and pharmacokinetic study of mithramycin in children and adults with refractory Ewing sarcoma and EWS–FLI1 fusion transcript

Cancer chemotherapy and pharmacology, 2017-09, Vol.80 (3), p.645-652

2017

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Phase 1 study of the immunotoxin LMB‐100 in patients with mesothelioma and other solid tumors expressing mesothelin

Cancer, 2020-11, Vol.126 (22), p.4936-4947

2020

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In Silico Re‐Optimization of Atezolizumab Dosing Using Population Pharmacokinetic Simulation and Exposure–Response Simulation

Journal of clinical pharmacology, 2023-06, Vol.63 (6), p.672-680

2023

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Alemtuzumab clearance, lymphocyte count, and T‐cell chimerism after hematopoietic stem cell transplant in sickle cell disease

Pharmacotherapy, 2022-01, Vol.42 (1), p.14-22

2022

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Pharmacogenomics and histone deacetylase inhibitors

Pharmacogenomics, 2016-11, Vol.17 (16), p.1807-1815

2016

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Optimized administration of hetIL-15 expands lymphocytes and minimizes toxicity in rhesus macaques

Cytokine (Philadelphia, Pa.), 2018-08, Vol.108, p.213-224

2018

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Cerebrospinal fluid penetration of the colony-stimulating factor-1 receptor (CSF-1R) inhibitor, pexidartinib

Cancer chemotherapy and pharmacology, 2020-05, Vol.85 (5), p.1003-1007

2020

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Sequence-Specific Pharmacokinetic and Pharmacodynamic Phase I/Ib Study of Olaparib Tablets and Carboplatin in Women's Cancer

Clinical cancer research, 2017-03, Vol.23 (6), p.1397-1406

2017

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Study to Compare Capsule and Liquid Formulations of Enzalutamide After Single‐Dose Administration Under Fasting Conditions in Prostate Cancer

The oncologist (Dayton, Ohio), 2021-09, Vol.26 (9), p.729-e1493

2021

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Measurement of NLG207 (formerly CRLX101) nanoparticle-bound and released camptothecin in human plasma

Journal of pharmaceutical and biomedical analysis, 2020-03, Vol.181, p.113073-113073, Article 113073

2020

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Evaluation of entinostat alone and in combination with standard‐of‐care cytotoxic agents against rhabdomyosarcoma xenograft models

Pediatric blood & cancer, 2019-08, Vol.66 (8), p.e27820-n/a

2019

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Characterizing the pharmacokinetics of panobinostat in a non-human primate model for the treatment of diffuse intrinsic pontine glioma

Cancer chemotherapy and pharmacology, 2020-04, Vol.85 (4), p.827-830

2020

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A population pharmacokinetic analysis of the oral CYP17 lyase and androgen receptor inhibitor seviteronel in patients with advanced/metastatic castration-resistant prostate cancer or breast cancer

Cancer chemotherapy and pharmacology, 2019-10, Vol.84 (4), p.759-770

2019

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Phase 1 study of sorafenib and irinotecan in pediatric patients with relapsed or refractory solid tumors

Pediatric blood & cancer, 2021-11, Vol.68 (11), p.e29282-n/a

2021

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A population pharmacokinetic/toxicity model for the reduction of platelets during a 48-h continuous intravenous infusion of the histone deacetylase inhibitor belinostat

Cancer chemotherapy and pharmacology, 2018-09, Vol.82 (3), p.565-570

2018

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Population pharmacokinetic analyses of the effect of carboplatin pretreatment on olaparib in recurrent or refractory women’s cancers

Cancer chemotherapy and pharmacology, 2017-07, Vol.80 (1), p.165-175

2017

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Quantitative modeling of the dynamics and intracellular trafficking of far-red light-activatable prodrugs: implications in stimuli-responsive drug delivery system

Journal of pharmacokinetics and pharmacodynamics, 2017-12, Vol.44 (6), p.521-536

2017

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Phase I study of single agent NIZ985, a recombinant heterodimeric IL-15 agonist, in adult patients with metastatic or unresectable solid tumors

Systemic immune changes accompany combination treatment with immunotoxin LMB‐100 and nab‐paclitaxel

Development and utilization of a combined LC–UV and LC–MS/MS method for the simultaneous analysis of tegafur and 5-fluorouracil in human plasma to support a phase I clinical study of oral UFT®/leucovorin

PARP inhibitors: A review of the pharmacology, pharmacokinetics, and pharmacogenetics

Pharmacokinetic Simulation Analysis of Less Frequent Nivolumab and Pembrolizumab Dosing: Pharmacoeconomic Rationale for Dose Deescalation

Phase I and Preliminary Phase II Study of TRC105 in Combination with Sorafenib in Hepatocellular Carcinoma

HSD3B1(1245A>C) variant regulates dueling abiraterone metabolite effects in prostate cancer

Alcohol and Aldehyde Dehydrogenases Contribute to Sex-Related Differences in Clearance of Zolpidem in Rats

A phase I/II trial and pharmacokinetic study of mithramycin in children and adults with refractory Ewing sarcoma and EWS–FLI1 fusion transcript

Phase 1 study of the immunotoxin LMB‐100 in patients with mesothelioma and other solid tumors expressing mesothelin

In Silico Re‐Optimization of Atezolizumab Dosing Using Population Pharmacokinetic Simulation and Exposure–Response Simulation

Alemtuzumab clearance, lymphocyte count, and T‐cell chimerism after hematopoietic stem cell transplant in sickle cell disease

Pharmacogenomics and histone deacetylase inhibitors

Optimized administration of hetIL-15 expands lymphocytes and minimizes toxicity in rhesus macaques

Cerebrospinal fluid penetration of the colony-stimulating factor-1 receptor (CSF-1R) inhibitor, pexidartinib

Sequence-Specific Pharmacokinetic and Pharmacodynamic Phase I/Ib Study of Olaparib Tablets and Carboplatin in Women's Cancer

Study to Compare Capsule and Liquid Formulations of Enzalutamide After Single‐Dose Administration Under Fasting Conditions in Prostate Cancer

Measurement of NLG207 (formerly CRLX101) nanoparticle-bound and released camptothecin in human plasma

Evaluation of entinostat alone and in combination with standard‐of‐care cytotoxic agents against rhabdomyosarcoma xenograft models

Characterizing the pharmacokinetics of panobinostat in a non-human primate model for the treatment of diffuse intrinsic pontine glioma

A population pharmacokinetic analysis of the oral CYP17 lyase and androgen receptor inhibitor seviteronel in patients with advanced/metastatic castration-resistant prostate cancer or breast cancer

Phase 1 study of sorafenib and irinotecan in pediatric patients with relapsed or refractory solid tumors

A population pharmacokinetic/toxicity model for the reduction of platelets during a 48-h continuous intravenous infusion of the histone deacetylase inhibitor belinostat

Population pharmacokinetic analyses of the effect of carboplatin pretreatment on olaparib in recurrent or refractory women’s cancers

Quantitative modeling of the dynamics and intracellular trafficking of far-red light-activatable prodrugs: implications in stimuli-responsive drug delivery system

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