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Do Phosphodiesterase Type 5 Inhibitors Increase the Risk of Biochemical Recurrence After Radical Prostatectomy?

The Journal of urology, 2024-03, Vol.211 (3), p.400-406

2024

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The first total syntheses of lorneic acids C and D and improved synthetic routes to lorneic acids A and J

Tetrahedron, 2024-08, Vol.163, p.134139, Article 134139

2024

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Therapeutic effects of mirodenafil, a phosphodiesterase 5 inhibitor, on stroke models in rats

Neurotherapeutics, 2024-10, p.e00463, Article e00463

2024

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Targeting the crosstalk between cytokine-induced killer cells and myeloid-derived suppressor cells in hepatocellular carcinoma

Journal of hepatology, 2019-03, Vol.70 (3), p.449-457

2019

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Tadalafil restores long-term memory and synaptic plasticity in mice with hepatic encephalopathy

Toxicology and applied pharmacology, 2019-09, Vol.379, p.114673, Article 114673

2019

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Facile and Cost-Effective Route for the Synthesis of Simmerafil

Organic process research & development, 2021-11, Vol.25 (11), p.2432-2437

2021

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Inhibition of PDE5 attenuates streptozotocin-induced neuroinflammation and tau hyperphosphorylation in a streptozotocin-treated rat model

Brain research, 2019-11, Vol.1722, p.146344-146344, Article 146344

2019

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NO‐mediated signal transmission in bladder vasculature as a therapeutic target of PDE5 inhibitors. Rodent model studies

British journal of pharmacology, 2021-03, Vol.178 (5), p.1073-1094

2021

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An Evaluation of a Clinical Care Pathway for the Management of Men With Nonorganic Erectile Dysfunction

Journal of sexual medicine, 2019-10, Vol.16 (10), p.1541-1546

2019

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Synthesis of quinoline derivatives: Discovery of a potent and selective phosphodiesterase 5 inhibitor for the treatment of Alzheimer's disease

European journal of medicinal chemistry, 2013-02, Vol.60, p.285-294

2013

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The effect of long-acting PDE-5 inhibitor on renal ischemia/ reperfusion injury in Wistar rats; a study on serum cystatin C and renal histopathological findings

Journal of nephropathology, 2019, Vol.8 (1), p.7-7

2019

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Phosphodiesterase Type 5 Inhibitors for the Treatment of Erectile Dysfunction: Pharmacology and Clinical Impact of the Sildenafil Citrate Orodispersible Tablet Formulation

Clinical therapeutics, 2017-02, Vol.39 (2), p.370-377

2017

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Phosphodiesterase 5 inhibition as a therapeutic target for ischemic stroke: A systematic review of preclinical studies

Cellular signalling, 2017-10, Vol.38, p.39-48

2017

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Incidence of erectile dysfunction treatment after radical prostatectomy by Statin use in Finnish Nationwide Cohort Study

Scandinavian journal of urology, 2023-11, Vol.57 (1-6), p.53-59

2023

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Repurposing erectile dysfunction drugs tadalafil and vardenafil to increase bone mass

Proceedings of the National Academy of Sciences - PNAS, 2020-06, Vol.117 (25), p.14386-14394

2020

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Diketopiperazine-Based, Flexible Tadalafil Analogues: Synthesis, Crystal Structures and Biological Activity Profile

Molecules (Basel, Switzerland), 2021-02, Vol.26 (4), p.794

2021

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Pharmacokinetics, mass balance, and metabolism of [14C]TPN171, a novel PDE5 inhibitor, in humans for the treatment of pulmonary arterial hypertension

Acta pharmacologica Sinica, 2023-01, Vol.44 (1), p.221-233

2023

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Protective effects of tadalafil on damaged podocytes in an adriamycin-induced nephrotic syndrome model

Journal of pharmacological sciences, 2022-06, Vol.149 (2), p.53-59

2022

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A Case of Sudden Sensorineural Hearing Loss Associated with Phosphodiesterase Type 5 Inhibitors

Practica oto-rhino-laryngologica. Suppl, 2018, Vol.152, p.6-7

2018

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Avanafil, a new rapid-onset phosphodiesterase 5 inhibitor for the treatment of erectile dysfunction

Expert opinion on investigational drugs, 2010-11, Vol.19 (11), p.1427-1437

2010

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3,7-Bis(2-hydroxyethyl)icaritin, a potent inhibitor of phosphodiesterase-5, prevents monocrotaline-induced pulmonary arterial hypertension via NO/cGMP activation in rats

European journal of pharmacology, 2018-06, Vol.829, p.102-111

2018

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The Rationale for Repurposing Sildenafil for Lung Cancer Treatment

Anti-cancer agents in medicinal chemistry, 2018-01, Vol.18 (3), p.367-374

2018

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Over-expression of PDE5 in Oral Squamous Cell Carcinoma - Effect of Sildenafil Citrate

Anticancer research, 2021-05, Vol.41 (5), p.2297-2306

2021

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Isolation and characterisation of a novel sildenafil analogue adulterant, desmethylpiperazinyl propoxysildenafil, in a dietary supplement

Science & justice, 2018-11, Vol.58 (6), p.447-454

2018

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Adverse reactions of PDE5 inhibitors: An analysis of the World Health Organization pharmacovigilance database

Andrology (Oxford), 2023-10, Vol.11 (7), p.1408-1417

2023

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Do Phosphodiesterase Type 5 Inhibitors Increase the Risk of Biochemical Recurrence After Radical Prostatectomy?

The first total syntheses of lorneic acids C and D and improved synthetic routes to lorneic acids A and J

Therapeutic effects of mirodenafil, a phosphodiesterase 5 inhibitor, on stroke models in rats

Targeting the crosstalk between cytokine-induced killer cells and myeloid-derived suppressor cells in hepatocellular carcinoma

Tadalafil restores long-term memory and synaptic plasticity in mice with hepatic encephalopathy

Facile and Cost-Effective Route for the Synthesis of Simmerafil

Inhibition of PDE5 attenuates streptozotocin-induced neuroinflammation and tau hyperphosphorylation in a streptozotocin-treated rat model

NO‐mediated signal transmission in bladder vasculature as a therapeutic target of PDE5 inhibitors. Rodent model studies

An Evaluation of a Clinical Care Pathway for the Management of Men With Nonorganic Erectile Dysfunction

Synthesis of quinoline derivatives: Discovery of a potent and selective phosphodiesterase 5 inhibitor for the treatment of Alzheimer's disease

The effect of long-acting PDE-5 inhibitor on renal ischemia/ reperfusion injury in Wistar rats; a study on serum cystatin C and renal histopathological findings

Phosphodiesterase Type 5 Inhibitors for the Treatment of Erectile Dysfunction: Pharmacology and Clinical Impact of the Sildenafil Citrate Orodispersible Tablet Formulation

Phosphodiesterase 5 inhibition as a therapeutic target for ischemic stroke: A systematic review of preclinical studies

Incidence of erectile dysfunction treatment after radical prostatectomy by Statin use in Finnish Nationwide Cohort Study

Repurposing erectile dysfunction drugs tadalafil and vardenafil to increase bone mass

Diketopiperazine-Based, Flexible Tadalafil Analogues: Synthesis, Crystal Structures and Biological Activity Profile

Pharmacokinetics, mass balance, and metabolism of [14C]TPN171, a novel PDE5 inhibitor, in humans for the treatment of pulmonary arterial hypertension

Protective effects of tadalafil on damaged podocytes in an adriamycin-induced nephrotic syndrome model

A Case of Sudden Sensorineural Hearing Loss Associated with Phosphodiesterase Type 5 Inhibitors

Avanafil, a new rapid-onset phosphodiesterase 5 inhibitor for the treatment of erectile dysfunction

3,7-Bis(2-hydroxyethyl)icaritin, a potent inhibitor of phosphodiesterase-5, prevents monocrotaline-induced pulmonary arterial hypertension via NO/cGMP activation in rats

The Rationale for Repurposing Sildenafil for Lung Cancer Treatment

Over-expression of PDE5 in Oral Squamous Cell Carcinoma - Effect of Sildenafil Citrate

Isolation and characterisation of a novel sildenafil analogue adulterant, desmethylpiperazinyl propoxysildenafil, in a dietary supplement

Adverse reactions of PDE5 inhibitors: An analysis of the World Health Organization pharmacovigilance database

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