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Management of Lower Urinary Tract Symptoms Attributed to Benign Prostatic Hyperplasia: AUA GUIDELINE PART I—Initial Work-up and Medical Management

The Journal of urology, 2021-10, Vol.206 (4), p.806-817

2021

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Repurposing of sildenafil as antitumour; induction of cyclic guanosine monophosphate/protein kinase G pathway, caspase-dependent apoptosis and pivotal reduction of Nuclear factor kappa light chain enhancer of activated B cells in lung cancer

Journal of pharmacy and pharmacology, 2021-08, Vol.73 (8), p.1080-1091

2021

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A Brief Overview of Cholinergic and Phosphodiesterase-5 Inhibitors in Diabetic Bladder Dysfunction

International journal of molecular sciences, 2024-10, Vol.25 (19), p.10704

2024

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Pentaclethra macrophylla leaves reduce blood glucose level, improve sexual behavior and modulate critical enzymes associated with diabetes-erectile dysfunction morbidity in rats

Journal of complementary & integrative medicine, 2024-03, Vol.21 (1), p.80-87

2024

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Haptoglobin treatment contributes to regulating nitric oxide signal and reduces oxidative stress in the penis: A preventive treatment for priapism in sickle cell disease

Frontiers in physiology, 2022-09, Vol.13, p.961534-961534

2022

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The differential roles of the two NO-GC isoforms in adjusting airway reactivity

American journal of physiology. Lung cellular and molecular physiology, 2022-10, Vol.323 (4), p.L450-L463

2022

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A Critical Analysis of the Role of Testosterone in Erectile Function: From Pathophysiology to Treatment—A Systematic Review

European urology, 2014-01, Vol.65 (1), p.99-112

2014

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Drug repurposing and structure-based discovery of new PDE4 and PDE5 inhibitors

European journal of medicinal chemistry, 2023-12, Vol.262, p.115893-115893, Article 115893

2023

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Icariin, a phoshphodiesterase-5 inhibitor, improves learning and memory in APP/PS1 transgenic mice by stimulation of NO/cGMP signalling

The international journal of neuropsychopharmacology, 2014-06, Vol.17 (6), p.871-881

2014

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Type 5 phosphodiesterase (PDE5) and the vascular tree: From embryogenesis to aging and disease

Mechanisms of ageing and development, 2020-09, Vol.190, p.111311-111311, Article 111311

2020

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The Reversal of Immune Exclusion Mediated by Tadalafil and an Anti-tumor Vaccine Also Induces PDL1 Upregulation in Recurrent Head and Neck Squamous Cell Carcinoma: Interim Analysis of a Phase I Clinical Trial

Frontiers in immunology, 2019-05, Vol.10, p.1206-1206

2019

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Hydroalcoholic Extract of Levisticum officinale Increases cGMP Signaling Pathway by Down-Regulating PDE5 Expression and Induction of Apoptosis in MCF-7 and MDA-MB-468 Breast Cancer Cell Lines

Iranian biomedical journal, 2019-07, Vol.23 (4), p.280-286

2019

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Intravascular hemolysis leads to exaggerated corpus cavernosum relaxation: Implication for priapism in sickle cell disease

The FASEB journal, 2022-10, Vol.36 (10), p.e22535-n/a

2022

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Targeting the SARS-CoV-2 3CL

Future cardiology, 2021-01, Vol.17 (5), p.765-768

2021

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Testosterone Deficiency in Sickle Cell Disease: Recognition and Remediation

Frontiers in endocrinology (Lausanne), 2022-05, Vol.13, p.892184-892184

2022

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Discovery of trisubstituted pyrazolines as a novel scaffold for the development of selective phosphodiesterase 5 inhibitors

Bioorganic chemistry, 2020-11, Vol.104, p.104322-104322, Article 104322

2020

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Lactic acid inhibits iNKT cell functions via a phosphodiesterase-5 dependent pathway

Biochemical and biophysical research communications, 2021-04, Vol.547, p.9-14

2021

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A Systematic Review and Meta-analysis on the Use of Phosphodiesterase 5 Inhibitors Alone or in Combination with α-Blockers for Lower Urinary Tract Symptoms Due to Benign Prostatic Hyperplasia

European urology, 2012-05, Vol.61 (5), p.994-1003

2012

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The PASTIS trial: Testing tadalafil for possible use in vascular cognitive impairment

Alzheimer's & dementia, 2022-12, Vol.18 (12), p.2393-2402

2022

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Sildenafil prevents HDACi-induced Epstein-Barr virus reactivation through the PKG pathway in NK/T cell lymphoma; potential implications for HDACi-mediated fatal complications

Antiviral research, 2021-05, Vol.189, p.105063-105063, Article 105063

2021

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The enigma of continual plasma volume expansion in pregnancy: critical role of the renin-angiotensin-aldosterone system

American journal of physiology. Renal physiology, 2016-12, Vol.311 (6), p.F1125-F1134

2016

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Ondas de choque de baja intensidad para la mejora en el tratamiento de la disfunción eréctil en pacientes no respondedores a PDE5-i: revisión sistemática

Revista internacional de andrologia, 2021-10, Vol.19 (4), p.272-280

2021

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Sildenafil inhibits the growth of human colorectal cancer in vitro and in vivo

American journal of cancer research, 2015-01, Vol.5 (11), p.3311-3324

2015

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Role of Phosphodiesterase 5 and Cyclic GMP in Hypertension

Current hypertension reports, 2016-05, Vol.18 (5), Article 39

2016

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Avanafil, a new rapid-onset phosphodiesterase 5 inhibitor for the treatment of erectile dysfunction

Expert opinion on investigational drugs, 2010-11, Vol.19 (11), p.1427-1437

2010

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Management of Lower Urinary Tract Symptoms Attributed to Benign Prostatic Hyperplasia: AUA GUIDELINE PART I—Initial Work-up and Medical Management

Repurposing of sildenafil as antitumour; induction of cyclic guanosine monophosphate/protein kinase G pathway, caspase-dependent apoptosis and pivotal reduction of Nuclear factor kappa light chain enhancer of activated B cells in lung cancer

A Brief Overview of Cholinergic and Phosphodiesterase-5 Inhibitors in Diabetic Bladder Dysfunction

Pentaclethra macrophylla leaves reduce blood glucose level, improve sexual behavior and modulate critical enzymes associated with diabetes-erectile dysfunction morbidity in rats

Haptoglobin treatment contributes to regulating nitric oxide signal and reduces oxidative stress in the penis: A preventive treatment for priapism in sickle cell disease

The differential roles of the two NO-GC isoforms in adjusting airway reactivity

A Critical Analysis of the Role of Testosterone in Erectile Function: From Pathophysiology to Treatment—A Systematic Review

Drug repurposing and structure-based discovery of new PDE4 and PDE5 inhibitors

Icariin, a phoshphodiesterase-5 inhibitor, improves learning and memory in APP/PS1 transgenic mice by stimulation of NO/cGMP signalling

Type 5 phosphodiesterase (PDE5) and the vascular tree: From embryogenesis to aging and disease

The Reversal of Immune Exclusion Mediated by Tadalafil and an Anti-tumor Vaccine Also Induces PDL1 Upregulation in Recurrent Head and Neck Squamous Cell Carcinoma: Interim Analysis of a Phase I Clinical Trial

Hydroalcoholic Extract of Levisticum officinale Increases cGMP Signaling Pathway by Down-Regulating PDE5 Expression and Induction of Apoptosis in MCF-7 and MDA-MB-468 Breast Cancer Cell Lines

Intravascular hemolysis leads to exaggerated corpus cavernosum relaxation: Implication for priapism in sickle cell disease

Targeting the SARS-CoV-2 3CL

Testosterone Deficiency in Sickle Cell Disease: Recognition and Remediation

Discovery of trisubstituted pyrazolines as a novel scaffold for the development of selective phosphodiesterase 5 inhibitors

Lactic acid inhibits iNKT cell functions via a phosphodiesterase-5 dependent pathway

A Systematic Review and Meta-analysis on the Use of Phosphodiesterase 5 Inhibitors Alone or in Combination with α-Blockers for Lower Urinary Tract Symptoms Due to Benign Prostatic Hyperplasia

The PASTIS trial: Testing tadalafil for possible use in vascular cognitive impairment

Sildenafil prevents HDACi-induced Epstein-Barr virus reactivation through the PKG pathway in NK/T cell lymphoma; potential implications for HDACi-mediated fatal complications

The enigma of continual plasma volume expansion in pregnancy: critical role of the renin-angiotensin-aldosterone system

Ondas de choque de baja intensidad para la mejora en el tratamiento de la disfunción eréctil en pacientes no respondedores a PDE5-i: revisión sistemática

Sildenafil inhibits the growth of human colorectal cancer in vitro and in vivo

Role of Phosphodiesterase 5 and Cyclic GMP in Hypertension

Avanafil, a new rapid-onset phosphodiesterase 5 inhibitor for the treatment of erectile dysfunction

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