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ABCB1/MDR1/P‐gp employs an ATP‐dependent twist‐and‐squeeze mechanism to export hydrophobic drugs

FEBS letters, 2021-03, Vol.595 (6), p.707-716

2021

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Inward- and outward-facing X-ray crystal structures of homodimeric P-glycoprotein CmABCB1

Nature communications, 2019-01, Vol.10 (1), p.88-88, Article 88

2019

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Live Cell FRET Analysis of the Conformational Changes of Human P-glycoprotein

Bio-protocol, 2021-02, Vol.11 (4), p.e3930-e3930

2021

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Structure–activity relationships of dibenzoylhydrazines for the inhibition of P-glycoprotein-mediated quinidine transport

Bioorganic & medicinal chemistry, 2016-07, Vol.24 (14), p.3184-3191

2016

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Functional role of the linker region in purified human P-glycoprotein

The FEBS journal, 2009-07, Vol.276 (13), p.3504-3516

2009

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Nonequivalent Nucleotide Trapping in the Two Nucleotide Binding Folds of the Human Multidrug Resistance Protein MRP1

The Journal of biological chemistry, 2000-06, Vol.275 (23), p.17626-17630

2000

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Anti-cancer drugs and glutathione stimulate vanadate-induced trapping of nucleotide in multidrug resistance-associated protein (MRP)

FEBS letters, 1997-01, Vol.401 (1), p.11-14

1997

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In vivo FRET analyses reveal a role of ATP hydrolysis–associated conformational changes in human P-glycoprotein

The Journal of biological chemistry, 2020-04, Vol.295 (15), p.5002-5011

2020

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In vitro and in vivo evaluations of the P-glycoprotein-mediated efflux of dibenzoylhydrazines

Toxicology and applied pharmacology, 2016-05, Vol.298, p.40-47

2016

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Inhibitory Effects of a Cyclosporin Derivative, SDZ PSC 833, on Transport of Doxorubicin and Vinblastine via Human P‐Glycoprotein

Cancer science, 1998-11, Vol.89 (11), p.1220-1228

1998

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Aureobasidin A, an antifungal cyclic depsipeptide antibiotic, is a substrate for both human MDR1 and MDR2/P-glycoproteins

FEBS letters, 1996-12, Vol.399 (1), p.29-32

1996

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P-glycoprotein-mediated transcellular transport of MDR-reversing agents

FEBS letters, 1993-06, Vol.324 (1), p.99-102

1993

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Quercetin, a bioflavonoid, inhibits the increase of human multidrug resistance gene ( MDR1) expression caused by arsenite

FEBS letters, 1992-04, Vol.301 (3), p.307-309

1992

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Effect of PCB-126 on intracellular accumulation and transepithelial transport of vinblastine in LLC-PK1 and its transformant cells expressing human P-glycoprotein

Journal of Veterinary Medical Science, 2004, Vol.66(9), pp.1079-1085

2004

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Human P-glycoprotein transports cyclosporin A and FK506

The Journal of biological chemistry, 1993-03, Vol.268 (9), p.6077-6080

1993

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Specific drug binding by purified lipid-reconstituted P-glycoprotein: Dependence on the lipid composition

Biochimica et biophysica acta, 1992-06, Vol.1107 (1), p.105-110

1992

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How does P-glycoprotein recognize its substrates?

Seminars in cancer biology, 1997-06, Vol.8 (3), p.151-159

1997

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Recent progress in P-glycoprotein research

Anti-cancer drug design, 1999-04, Vol.14 (2), p.115

1999

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Heat-shock responsive elements in the induction of the multidrug resistance gene ( MDR1)

FEBS letters, 1992-04, Vol.301 (1), p.37-40

1992

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Genomic organization of the human multidrug resistance (MDR1) gene and origin of P-glycoproteins

The Journal of biological chemistry, 1990-01, Vol.265 (1), p.506-514

1990

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Amino acid substitutions in the first transmembrane domain (TM1) of P-glycoprotein that alter substrate specificity

FEBS letters, 1997-08, Vol.413 (1), p.142-146

1997

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MDR 1/P-glycoprotein: An Efflux Pump of Lipophilic Xenobiotics

Nippon Nōgeikagaku Kaishi, 1997/08/01, Vol.71(8), pp.785-788

UEDA, Kazumitsu

1997

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Effect of cyclosporin analogues and FK506 on transcellular transport of daunorubicin and vinblastine via P-glycoprotein

Pharmaceutical research, 1996-07, Vol.13 (7), p.1073-1077

1996

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Relationship between expression level of P-glycoprotein and daunorubicin transport in LLC-PK1 cells transfected with human MDR1 gene

Biochemical pharmacology, 1997-03, Vol.53 (5), p.741-746

1997

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Molecular Mechanism of Defence to Toxic Substance

Nippon Nōgeikagaku Kaishi, 2000/07/01, Vol.74(7), pp.791-794

2000

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ABCB1/MDR1/P‐gp employs an ATP‐dependent twist‐and‐squeeze mechanism to export hydrophobic drugs

Inward- and outward-facing X-ray crystal structures of homodimeric P-glycoprotein CmABCB1

Live Cell FRET Analysis of the Conformational Changes of Human P-glycoprotein

Structure–activity relationships of dibenzoylhydrazines for the inhibition of P-glycoprotein-mediated quinidine transport

Functional role of the linker region in purified human P-glycoprotein

Nonequivalent Nucleotide Trapping in the Two Nucleotide Binding Folds of the Human Multidrug Resistance Protein MRP1

Anti-cancer drugs and glutathione stimulate vanadate-induced trapping of nucleotide in multidrug resistance-associated protein (MRP)

In vivo FRET analyses reveal a role of ATP hydrolysis–associated conformational changes in human P-glycoprotein

In vitro and in vivo evaluations of the P-glycoprotein-mediated efflux of dibenzoylhydrazines

Inhibitory Effects of a Cyclosporin Derivative, SDZ PSC 833, on Transport of Doxorubicin and Vinblastine via Human P‐Glycoprotein

Aureobasidin A, an antifungal cyclic depsipeptide antibiotic, is a substrate for both human MDR1 and MDR2/P-glycoproteins

P-glycoprotein-mediated transcellular transport of MDR-reversing agents

Quercetin, a bioflavonoid, inhibits the increase of human multidrug resistance gene ( MDR1) expression caused by arsenite

Effect of PCB-126 on intracellular accumulation and transepithelial transport of vinblastine in LLC-PK1 and its transformant cells expressing human P-glycoprotein

Human P-glycoprotein transports cyclosporin A and FK506

Specific drug binding by purified lipid-reconstituted P-glycoprotein: Dependence on the lipid composition

How does P-glycoprotein recognize its substrates?

Recent progress in P-glycoprotein research

Heat-shock responsive elements in the induction of the multidrug resistance gene ( MDR1)

Genomic organization of the human multidrug resistance (MDR1) gene and origin of P-glycoproteins

Amino acid substitutions in the first transmembrane domain (TM1) of P-glycoprotein that alter substrate specificity

MDR 1/P-glycoprotein: An Efflux Pump of Lipophilic Xenobiotics

Effect of cyclosporin analogues and FK506 on transcellular transport of daunorubicin and vinblastine via P-glycoprotein

Relationship between expression level of P-glycoprotein and daunorubicin transport in LLC-PK1 cells transfected with human MDR1 gene

Molecular Mechanism of Defence to Toxic Substance

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