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Integrated pan-cancer gene expression and drug sensitivity analysis reveals SLFN11 mRNA as a solid tumor biomarker predictive of sensitivity to DNA-damaging chemotherapy

PloS one, 2019-11, Vol.14 (11), p.e0224267

2019

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Phosphatidylinositol 3-Kinase and Antiestrogen Resistance in Breast Cancer

Journal of clinical oncology, 2011-11, Vol.29 (33), p.4452-4461

2011

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Mutations in the phosphatidylinositol 3-kinase pathway: role in tumor progression and therapeutic implications in breast cancer

Breast cancer research : BCR, 2011-11, Vol.13 (6), p.224-224, Article 224

2011

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The role of cancer cell bioenergetics in dormancy and drug resistance

Cancer and metastasis reviews, 2023-03, Vol.42 (1), p.87-98

2023

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Alpelisib Efficacy without Cherry-PI3King Mutations

Clinical cancer research, 2023-03, Vol.29 (6), p.989-990

2023

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Changes in Peripheral and Local Tumor Immunity after Neoadjuvant Chemotherapy Reshape Clinical Outcomes in Patients with Breast Cancer

Clinical cancer research, 2020-11, Vol.26 (21), p.5668-5681

2020

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Biomarkers of Response to Akt Inhibitor MK-2206 in Breast Cancer

Clinical cancer research, 2012-10, Vol.18 (20), p.5816-5828

2012

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AMPK Activation by Metformin Promotes Survival of Dormant ER + Breast Cancer Cells

Clinical cancer research, 2020-07, Vol.26 (14), p.3707-3719

2020

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Trailblazing Precision Oncology for Rare Tumor Subtypes

The oncologist (Dayton, Ohio), 2018-02, Vol.23 (2), p.143-144

2018

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Loss of Phosphatase and Tensin Homologue Deleted on Chromosome 10 Engages ErbB3 and Insulin-Like Growth Factor-I Receptor Signaling to Promote Antiestrogen Resistance in Breast Cancer

Cancer research (Chicago, Ill.), 2009-05, Vol.69 (10), p.4192-4201

2009

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Initiating breast cancer by PIK3CA mutation

Breast cancer research : BCR, 2012-02, Vol.14 (1), p.301-301, Article 301

Miller, Todd W

2012

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A Kinome-Wide Screen Identifies the Insulin/IGF-I Receptor Pathway as a Mechanism of Escape from Hormone Dependence in Breast Cancer

Cancer research (Chicago, Ill.), 2011-11, Vol.71 (21), p.6773-6784

2011

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Activation of MAPK Pathways due to DUSP4 Loss Promotes Cancer Stem Cell-like Phenotypes in Basal-like Breast Cancer

Cancer research (Chicago, Ill.), 2013-10, Vol.73 (20), p.6346-6358

2013

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High estrogen receptor alpha activation confers resistance to estrogen deprivation and is required for therapeutic response to estrogen in breast cancer

Oncogene, 2021-05, Vol.40 (19), p.3408-3421

2021

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Managing Breast Cancers with Low Estrogen Receptor and HER2 by Drugging Both

Clinical cancer research, 2014-02, Vol.20 (3), p.528-530

MILLER, Todd W

2014

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ERα-dependent E2F transcription can mediate resistance to estrogen deprivation in human breast cancer

Cancer discovery, 2011-09, Vol.1 (4), p.338-351

2011

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Implementation of a Molecular Tumor Board: The Impact on Treatment Decisions for 35 Patients Evaluated at Dartmouth‐Hitchcock Medical Center

The oncologist (Dayton, Ohio), 2015-09, Vol.20 (9), p.1011-1018

2015

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TRIM33 Is a Co-Regulator of Estrogen Receptor Alpha

Cancers, 2024-02, Vol.16 (5), p.845

2024

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Tumor pharmacokinetics and pharmacodynamics of the CDK4/6 inhibitor ribociclib in patients with recurrent glioblastoma

Journal of neuro-oncology, 2019-09, Vol.144 (3), p.563-572

2019

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Autocrine IGF-I/insulin receptor axis compensates for inhibition of AKT in ER-positive breast cancer cells with resistance to estrogen deprivation

Breast cancer research : BCR, 2013-07, Vol.15 (4), p.R55-R55, Article R55

2013

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Molecular and epigenetic profiles of BRCA1-like hormone-receptor-positive breast tumors identified with development and application of a copy-number-based classifier

Breast cancer research : BCR, 2019-01, Vol.21 (1), p.14-14, Article 14

2019

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Inhibition of Mammalian Target of Rapamycin Is Required for Optimal Antitumor Effect of HER2 Inhibitors against HER2-Overexpressing Cancer Cells

Clinical cancer research, 2009-12, Vol.15 (23), p.7266-7276

2009

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Pan-Cancer Transcriptional Models Predicting Chemosensitivity in Human Tumors

Cancer informatics, 2021-01, Vol.20, p.11769351211002494-11769351211002494

2021

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A Gene Expression Signature from Human Breast Cancer Cells with Acquired Hormone Independence Identifies MYC as a Mediator of Antiestrogen Resistance

Clinical cancer research, 2011-04, Vol.17 (7), p.2024-2034

2011

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Combined Inhibition of Both p110α and p110β Isoforms of Phosphatidylinositol 3-Kinase Is Required for Sustained Therapeutic Effect in PTEN-Deficient, ER + Breast Cancer

Clinical cancer research, 2017-06, Vol.23 (11), p.2795-2805

2017

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Integrated pan-cancer gene expression and drug sensitivity analysis reveals SLFN11 mRNA as a solid tumor biomarker predictive of sensitivity to DNA-damaging chemotherapy

Phosphatidylinositol 3-Kinase and Antiestrogen Resistance in Breast Cancer

Mutations in the phosphatidylinositol 3-kinase pathway: role in tumor progression and therapeutic implications in breast cancer

The role of cancer cell bioenergetics in dormancy and drug resistance

Alpelisib Efficacy without Cherry-PI3King Mutations

Changes in Peripheral and Local Tumor Immunity after Neoadjuvant Chemotherapy Reshape Clinical Outcomes in Patients with Breast Cancer

Biomarkers of Response to Akt Inhibitor MK-2206 in Breast Cancer

AMPK Activation by Metformin Promotes Survival of Dormant ER + Breast Cancer Cells

Trailblazing Precision Oncology for Rare Tumor Subtypes

Loss of Phosphatase and Tensin Homologue Deleted on Chromosome 10 Engages ErbB3 and Insulin-Like Growth Factor-I Receptor Signaling to Promote Antiestrogen Resistance in Breast Cancer

Initiating breast cancer by PIK3CA mutation

A Kinome-Wide Screen Identifies the Insulin/IGF-I Receptor Pathway as a Mechanism of Escape from Hormone Dependence in Breast Cancer

Activation of MAPK Pathways due to DUSP4 Loss Promotes Cancer Stem Cell-like Phenotypes in Basal-like Breast Cancer

High estrogen receptor alpha activation confers resistance to estrogen deprivation and is required for therapeutic response to estrogen in breast cancer

Managing Breast Cancers with Low Estrogen Receptor and HER2 by Drugging Both

ERα-dependent E2F transcription can mediate resistance to estrogen deprivation in human breast cancer

Implementation of a Molecular Tumor Board: The Impact on Treatment Decisions for 35 Patients Evaluated at Dartmouth‐Hitchcock Medical Center

TRIM33 Is a Co-Regulator of Estrogen Receptor Alpha

Tumor pharmacokinetics and pharmacodynamics of the CDK4/6 inhibitor ribociclib in patients with recurrent glioblastoma

Autocrine IGF-I/insulin receptor axis compensates for inhibition of AKT in ER-positive breast cancer cells with resistance to estrogen deprivation

Molecular and epigenetic profiles of BRCA1-like hormone-receptor-positive breast tumors identified with development and application of a copy-number-based classifier

Inhibition of Mammalian Target of Rapamycin Is Required for Optimal Antitumor Effect of HER2 Inhibitors against HER2-Overexpressing Cancer Cells

Pan-Cancer Transcriptional Models Predicting Chemosensitivity in Human Tumors

A Gene Expression Signature from Human Breast Cancer Cells with Acquired Hormone Independence Identifies MYC as a Mediator of Antiestrogen Resistance

Combined Inhibition of Both p110α and p110β Isoforms of Phosphatidylinositol 3-Kinase Is Required for Sustained Therapeutic Effect in PTEN-Deficient, ER + Breast Cancer

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