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Killing zombies: Senolytic therapy in pilocytic astrocytoma

Neuro-oncology (Charlottesville, Va.), 2023-04, Vol.25 (4), p.748-749

Eberhart, Charles G

2023

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Medulloblastoma Comprises Four Distinct Molecular Variants

Journal of clinical oncology, 2011-04, Vol.29 (11), p.1408-1414

2011

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Integrative Genomic Analysis of Medulloblastoma Identifies a Molecular Subgroup That Drives Poor Clinical Outcome

Journal of clinical oncology, 2011-04, Vol.29 (11), p.1424-1430

2011

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Medulloblastoma Stem Cells

Journal of clinical oncology, 2008-06, Vol.26 (17), p.2821-2827

2008

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Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors

Cancer research (Chicago, Ill.), 2006-08, Vol.66 (15), p.7445-7452

2006

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Cyclopamine‐Mediated Hedgehog Pathway Inhibition Depletes Stem‐Like Cancer Cells in Glioblastoma

Stem cells (Dayton, Ohio), 2007-10, Vol.25 (10), p.2524-2533

2007

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A polymeric nanoparticle formulation of curcumin inhibits growth, clonogenicity and stem-like fraction in malignant brain tumors

Cancer biology & therapy, 2011-03, Vol.11 (5), p.464-473

2011

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Subgroup-Specific Prognostic Implications of TP53 Mutation in Medulloblastoma

Journal of clinical oncology, 2013-08, Vol.31 (23), p.2927-2935

2013

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Synergistic activity of mTORC1/2 kinase and MEK inhibitors suppresses pediatric low-grade glioma tumorigenicity and vascularity

Neuro-oncology (Charlottesville, Va.), 2020-04, Vol.22 (4), p.563-574

2020

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NOTCH Pathway Blockade Depletes CD133‐Positive Glioblastoma Cells and Inhibits Growth of Tumor Neurospheres and Xenografts

Stem cells (Dayton, Ohio), 2010-01, Vol.28 (1), p.5-16

2010

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HMMR Maintains the Stemness and Tumorigenicity of Glioblastoma Stem-like Cells

Cancer research (Chicago, Ill.), 2014-06, Vol.74 (11), p.3168-3179

2014

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ATRX loss induces multiple hallmarks of the alternative lengthening of telomeres (ALT) phenotype in human glioma cell lines in a cell line-specific manner

PloS one, 2018-09, Vol.13 (9), p.e0204159-e0204159

2018

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MYC Drives Group 3 Medulloblastoma through Transformation of Sox2 + Astrocyte Progenitor Cells

Cancer research (Chicago, Ill.), 2019-04, Vol.79 (8), p.1967-1980

2019

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Frondoside A Inhibits an MYC-Driven Medulloblastoma Model Derived from Human-Induced Pluripotent Stem Cells

Molecular cancer therapeutics, 2021-06, Vol.20 (6), p.1199-1209

2021

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The dual mTOR kinase inhibitor TAK228 inhibits tumorigenicity and enhances radiosensitization in diffuse intrinsic pontine glioma

Cancer letters, 2017-08, Vol.400, p.110-116

2017

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The Notch Target Hes1 Directly Modulates Gli1 Expression and Hedgehog Signaling: A Potential Mechanism of Therapeutic Resistance

Clinical cancer research, 2010-12, Vol.16 (24), p.6060-6070

2010

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RNA binding protein RBM14 promotes radio-resistance in glioblastoma by regulating DNA repair and cell differentiation

Oncotarget, 2014-05, Vol.5 (9), p.2820-2826

2014

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Pediatric and adult sonic hedgehog medulloblastomas are clinically and molecularly distinct

Acta neuropathologica, 2011-08, Vol.122 (2), p.231-240

2011

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Three Down and One To Go: Modeling Medulloblastoma Subgroups

Cancer cell, 2012-02, Vol.21 (2), p.137-138

Eberhart, Charles G.

2012

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Orally bioavailable glutamine antagonist prodrug JHU-083 penetrates mouse brain and suppresses the growth of MYC-driven medulloblastoma

Translational oncology, 2019-10, Vol.12 (10), p.1314-1322

2019

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Prolonged inhibition of glioblastoma xenograft initiation and clonogenic growth following in vivo Notch blockade

Clinical cancer research, 2013-06, Vol.19 (12), p.3224-3233

2013

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Alterations in cellular metabolome after pharmacological inhibition of Notch in glioblastoma cells

International journal of cancer, 2016-03, Vol.138 (5), p.1246-1255

2016

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Ligand-dependent Notch Signaling Is Involved in Tumor Initiation and Tumor Maintenance in Pancreatic Cancer

Clinical cancer research, 2009-04, Vol.15 (7), p.2291-2301

2009

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Cordycepin (3′-Deoxyadenosine) Suppresses Heat Shock Protein 90 Function and Targets Tumor Growth in an Adenosine Deaminase-Dependent Manner

Cancers, 2022-06, Vol.14 (13), p.3122

2022

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Establishment and Biological Characterization of a Panel of Glioblastoma Multiforme (GBM) and GBM Variant Oncosphere Cell Lines

PloS one, 2016-03, Vol.11 (3), p.e0150271-e0150271

2016

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Killing zombies: Senolytic therapy in pilocytic astrocytoma

Medulloblastoma Comprises Four Distinct Molecular Variants

Integrative Genomic Analysis of Medulloblastoma Identifies a Molecular Subgroup That Drives Poor Clinical Outcome

Medulloblastoma Stem Cells

Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors

Cyclopamine‐Mediated Hedgehog Pathway Inhibition Depletes Stem‐Like Cancer Cells in Glioblastoma

A polymeric nanoparticle formulation of curcumin inhibits growth, clonogenicity and stem-like fraction in malignant brain tumors

Subgroup-Specific Prognostic Implications of TP53 Mutation in Medulloblastoma

Synergistic activity of mTORC1/2 kinase and MEK inhibitors suppresses pediatric low-grade glioma tumorigenicity and vascularity

NOTCH Pathway Blockade Depletes CD133‐Positive Glioblastoma Cells and Inhibits Growth of Tumor Neurospheres and Xenografts

HMMR Maintains the Stemness and Tumorigenicity of Glioblastoma Stem-like Cells

ATRX loss induces multiple hallmarks of the alternative lengthening of telomeres (ALT) phenotype in human glioma cell lines in a cell line-specific manner

MYC Drives Group 3 Medulloblastoma through Transformation of Sox2 + Astrocyte Progenitor Cells

Frondoside A Inhibits an MYC-Driven Medulloblastoma Model Derived from Human-Induced Pluripotent Stem Cells

The dual mTOR kinase inhibitor TAK228 inhibits tumorigenicity and enhances radiosensitization in diffuse intrinsic pontine glioma

The Notch Target Hes1 Directly Modulates Gli1 Expression and Hedgehog Signaling: A Potential Mechanism of Therapeutic Resistance

RNA binding protein RBM14 promotes radio-resistance in glioblastoma by regulating DNA repair and cell differentiation

Pediatric and adult sonic hedgehog medulloblastomas are clinically and molecularly distinct

Three Down and One To Go: Modeling Medulloblastoma Subgroups

Orally bioavailable glutamine antagonist prodrug JHU-083 penetrates mouse brain and suppresses the growth of MYC-driven medulloblastoma

Prolonged inhibition of glioblastoma xenograft initiation and clonogenic growth following in vivo Notch blockade

Alterations in cellular metabolome after pharmacological inhibition of Notch in glioblastoma cells

Ligand-dependent Notch Signaling Is Involved in Tumor Initiation and Tumor Maintenance in Pancreatic Cancer

Cordycepin (3′-Deoxyadenosine) Suppresses Heat Shock Protein 90 Function and Targets Tumor Growth in an Adenosine Deaminase-Dependent Manner

Establishment and Biological Characterization of a Panel of Glioblastoma Multiforme (GBM) and GBM Variant Oncosphere Cell Lines

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