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PDE5A inhibition attenuates bleomycin-induced pulmonary fibrosis and pulmonary hypertension through inhibition of ROS generation and RhoA/Rho kinase activation

American journal of physiology. Lung cellular and molecular physiology, 2008-01, Vol.294 (1), p.L24-L33

2008

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Arginase inhibition restores NOS coupling and reverses endothelial dysfunction and vascular stiffness in old rats

Journal of applied physiology (1985), 2009-10, Vol.107 (4), p.1249-1257

2009

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Oxidant stress from nitric oxide synthase-3 uncoupling stimulates cardiac pathologic remodeling from chronic pressure load

The Journal of clinical investigation, 2005-05, Vol.115 (5), p.1221-1231

2005

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Sildenafil citrate-restored eNOS and PDE5 regulation in sickle cell mouse penis prevents priapism via control of oxidative/nitrosative stress

PloS one, 2013-07, Vol.8 (7), p.e68028-e68028

2013

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Arginase reciprocally regulates nitric oxide synthase activity and contributes to endothelial dysfunction in aging blood vessels

Circulation (New York, N.Y.), 2003-10, Vol.108 (16), p.2000-2006

2003

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Phosphodiesterase-5A Dysregulation in Penile Erectile Tissue Is a Mechanism of Priapism

Proceedings of the National Academy of Sciences - PNAS, 2005-02, Vol.102 (5), p.1661-1666

2005

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RhoA/Rho-Kinase Suppresses Endothelial Nitric Oxide Synthase in the Penis: A Mechanism for Diabetes-Associated Erectile Dysfunction

Proceedings of the National Academy of Sciences - PNAS, 2004-06, Vol.101 (24), p.9121-9126

2004

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Positive Inotropic and Lusitropic Effects of HNO/NO-in Failing Hearts: Independence from β-Adrenergic Signaling

Proceedings of the National Academy of Sciences - PNAS, 2003-04, Vol.100 (9), p.5537-5542

2003

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Pulmonary Arterial Hypertension: The Clinical Syndrome

Circulation research, 2014-06, Vol.115 (1), p.115-130

2014

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Mechanisms and potential therapeutic targets for folic acid in cardiovascular disease

American journal of physiology. Heart and circulatory physiology, 2008-05, Vol.294 (5), p.H1971-H1977

2008

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Endothelial Nitric Oxide Synthase Keeps Erection Regulatory Function Balance in the Penis

European urology, 2007-06, Vol.51 (6), p.1732-1740

2007

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Establishment of a Transgenic Sickle-Cell Mouse Model to Study the Pathophysiology of Priapism

Journal of sexual medicine, 2009-09, Vol.6 (9), p.2494-2504

2009

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Superoxide anion production in the rat penis impairs erectile function in diabetes: influence of in vivo extracellular superoxide dismutase gene therapy

Journal of sexual medicine, 2005-03, Vol.2 (2), p.187-198

2005

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Adenoviral Gene Transfer of Endothelial Nitric-Oxide Synthase (eNOS) Partially Restores Normal Pulmonary Arterial Pressure in eNOS-Deficient Mice

Proceedings of the National Academy of Sciences - PNAS, 2002-10, Vol.99 (20), p.13248-13253

2002

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Endothelial Arginase II: A Novel Target for the Treatment of Atherosclerosis

Circulation research, 2008-04, Vol.102 (8), p.923-932

2008

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Alternatively Spliced Neuronal Nitric Oxide Synthase Mediates Penile Erection

Proceedings of the National Academy of Sciences - PNAS, 2006-02, Vol.103 (9), p.3440-3443

2006

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Early changes in vasoreactivity after simulated microgravity are due to an upregulation of the endothelium-dependent nitric oxide/cGMP pathway

European journal of applied physiology, 2010-09, Vol.110 (2), p.395-404

2010

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Mesenchymal stem cells alone or ex vivo gene modified with endothelial nitric oxide synthase reverse age-associated erectile dysfunction

American journal of physiology. Heart and circulatory physiology, 2007-03, Vol.292 (3), p.H1278-H1290

2007

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Knockdown of Arginase I Restores NO Signaling in the Vasculature of Old Rats

Hypertension (Dallas, Tex. 1979), 2006-02, Vol.47 (2), p.245-251

2006

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Overexpression of arginase in the aged mouse penis impairs erectile function and decreases eNOS activity: influence of in vivo gene therapy of anti-arginase

American journal of physiology. Heart and circulatory physiology, 2007-03, Vol.292 (3), p.H1340-H1351

2007

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Decreased Exhaled Nitric Oxide in Pulmonary Arterial Hypertension: Response to Bosentan Therapy

American journal of respiratory and critical care medicine, 2005-08, Vol.172 (3), p.352-357

2005

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Exposure to inhaled particulate matter impairs cardiac function in senescent mice

American journal of physiology. Regulatory, integrative and comparative physiology, 2008-07, Vol.295 (1), p.R252-R263

2008

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Increased Expression of Arginase II in Human Diabetic Corpus Cavernosum: In Diabetic-Associated Erectile Dysfunction

Biochemical and biophysical research communications, 2001-05, Vol.283 (4), p.923-927

2001

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Gene transfer of extracellular SOD to the penis reduces O2−{middle dot} and improves erectile function in aged rats

American journal of physiology. Heart and circulatory physiology, 2003-04, Vol.284 (4), p.H1408-H1421

2003

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Gene therapy for erectile dysfunction : Fact or fiction?

European urology, 2006-12, Vol.50 (6), p.1208-1222

2006

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PDE5A inhibition attenuates bleomycin-induced pulmonary fibrosis and pulmonary hypertension through inhibition of ROS generation and RhoA/Rho kinase activation

Arginase inhibition restores NOS coupling and reverses endothelial dysfunction and vascular stiffness in old rats

Oxidant stress from nitric oxide synthase-3 uncoupling stimulates cardiac pathologic remodeling from chronic pressure load

Sildenafil citrate-restored eNOS and PDE5 regulation in sickle cell mouse penis prevents priapism via control of oxidative/nitrosative stress

Arginase reciprocally regulates nitric oxide synthase activity and contributes to endothelial dysfunction in aging blood vessels

Phosphodiesterase-5A Dysregulation in Penile Erectile Tissue Is a Mechanism of Priapism

RhoA/Rho-Kinase Suppresses Endothelial Nitric Oxide Synthase in the Penis: A Mechanism for Diabetes-Associated Erectile Dysfunction

Positive Inotropic and Lusitropic Effects of HNO/NO-in Failing Hearts: Independence from β-Adrenergic Signaling

Pulmonary Arterial Hypertension: The Clinical Syndrome

Mechanisms and potential therapeutic targets for folic acid in cardiovascular disease

Endothelial Nitric Oxide Synthase Keeps Erection Regulatory Function Balance in the Penis

Establishment of a Transgenic Sickle-Cell Mouse Model to Study the Pathophysiology of Priapism

Superoxide anion production in the rat penis impairs erectile function in diabetes: influence of in vivo extracellular superoxide dismutase gene therapy

Adenoviral Gene Transfer of Endothelial Nitric-Oxide Synthase (eNOS) Partially Restores Normal Pulmonary Arterial Pressure in eNOS-Deficient Mice

Endothelial Arginase II: A Novel Target for the Treatment of Atherosclerosis

Alternatively Spliced Neuronal Nitric Oxide Synthase Mediates Penile Erection

Early changes in vasoreactivity after simulated microgravity are due to an upregulation of the endothelium-dependent nitric oxide/cGMP pathway

Mesenchymal stem cells alone or ex vivo gene modified with endothelial nitric oxide synthase reverse age-associated erectile dysfunction

Knockdown of Arginase I Restores NO Signaling in the Vasculature of Old Rats

Overexpression of arginase in the aged mouse penis impairs erectile function and decreases eNOS activity: influence of in vivo gene therapy of anti-arginase

Decreased Exhaled Nitric Oxide in Pulmonary Arterial Hypertension: Response to Bosentan Therapy

Exposure to inhaled particulate matter impairs cardiac function in senescent mice

Increased Expression of Arginase II in Human Diabetic Corpus Cavernosum: In Diabetic-Associated Erectile Dysfunction

Gene transfer of extracellular SOD to the penis reduces O2−{middle dot} and improves erectile function in aged rats

Gene therapy for erectile dysfunction : Fact or fiction?

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