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Attenuating nicotine’s effects with high affinity human anti-nicotine monoclonal antibodies

PloS one, 2021-07, Vol.16 (7), p.e0254247

2021

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The relative reinforcing efficacy of nicotine in an adolescent rat model of attention-deficit hyperactivity disorder

Frontiers in psychiatry, 2023-05, Vol.14, p.1154773-1154773

2023

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Effects of an oxycodone conjugate vaccine on oxycodone self-administration and oxycodone-induced brain gene expression in rats

PloS one, 2014-07, Vol.9 (7), p.e101807

2014

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Cigarette Smoke Extract, but Not Electronic Cigarette Aerosol Extract, Inhibits Monoamine Oxidase in vitro and Produces Greater Acute Aversive/Anhedonic Effects Than Nicotine Alone on Intracranial Self-Stimulation in Rats

Frontiers in neuroscience, 2022-05, Vol.16, p.868088-868088

2022

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Effects of nicotine and minor tobacco alkaloids on intracranial-self-stimulation in rats

Drug and alcohol dependence, 2015-08, Vol.153, p.330-334

2015

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Stimulus functions of nicotine

Advances in pharmacology (1990), 2022, Vol.93, p.133-170

LeSage, Mark G

2022

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The nicotine-degrading enzyme NicA2 reduces nicotine levels in blood, nicotine distribution to brain, and nicotine discrimination and reinforcement in rats

BMC biotechnology, 2018-07, Vol.18 (1), p.46-14, Article 46

2018

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Substitutability of nicotine and sucrose in rats: A behavioral economic analysis

Pharmacology, biochemistry and behavior, 2023-11, Vol.232, p.173635-173635, Article 173635

2023

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β-Carbolines found in cigarette smoke elevate intracranial self-stimulation thresholds in rats

Pharmacology, biochemistry and behavior, 2020-11, Vol.198, p.173041-173041, Article 173041

2020

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New Directions in Nicotine Vaccine Design and Use

Advances in Pharmacology, 2014, Vol.69, p.553-580

2014

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The reinforcement threshold for nicotine as a target for tobacco control

Drug and alcohol dependence, 2012-09, Vol.125 (1), p.1-7

2012

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The reinforcement threshold and elasticity of demand for nicotine in an adolescent rat model of depression

Drug and alcohol dependence, 2021-02, Vol.219, p.108433-108433, Article 108433

2021

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Propylene glycol, a major electronic cigarette constituent, attenuates the adverse effects of high-dose nicotine as measured by intracranial self-stimulation in rats

Drug and alcohol dependence, 2018-12, Vol.193, p.162-168

2018

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Substitutability of nicotine alone and an electronic cigarette liquid using a concurrent choice assay in rats: A behavioral economic analysis

Drug and alcohol dependence, 2018-04, Vol.185, p.58-66

2018

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Toward a nonhuman model of contingency management: effects of reinforcing abstinence from nicotine self-administration in rats with an alternative nondrug reinforcer

Psychopharmacologia, 2009-03, Vol.203 (1), p.13-22

LeSage, Mark G.

2009

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Non-nicotine constituents in e-cigarette aerosol extract attenuate nicotine’s aversive effects in adolescent rats

Drug and alcohol dependence, 2019-10, Vol.203, p.51-60

2019

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Comparison of the Relative Abuse Liability of Electronic Cigarette Aerosol Extracts and Nicotine Alone in Adolescent Rats: A Behavioral Economic Analysis

International journal of environmental research and public health, 2020-01, Vol.17 (3), p.860

2020

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Restraint stress attenuates nicotine's locomotor stimulant but not discriminative stimulus effects in rats

Pharmacology, biochemistry and behavior, 2014-09, Vol.124, p.92-100

2014

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A lack of association between severity of nicotine withdrawal and individual differences in compensatory nicotine self-administration in rats

Psychopharmacologia, 2011-09, Vol.217 (2), p.153-166

2011

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Animal models to assess the abuse liability of tobacco products: Effects of smokeless tobacco extracts on intracranial self-stimulation

Drug and alcohol dependence, 2015-02, Vol.147, p.60-67

2015

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Delivery of nicotine in an extract of a smokeless tobacco product reduces its reinforcement-attenuating and discriminative stimulus effects in rats

Psychopharmacologia, 2012-04, Vol.220 (3), p.565-576

2012

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Nicotine reduction revisited: science and future directions

Tobacco control, 2010-10, Vol.19 (5), p.e1-e1

2010

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Effects of the nicotinic receptor partial agonists varenicline and cytisine on the discriminative stimulus effects of nicotine in rats

Pharmacology, biochemistry and behavior, 2009-01, Vol.91 (3), p.461-467

2009

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Enhanced attenuation of nicotine discrimination in rats by combining nicotine-specific antibodies with a nicotinic receptor antagonist

Pharmacology, biochemistry and behavior, 2012-07, Vol.102 (1), p.157-162

2012

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Comparison of the behavioral effects of cigarette smoke and pure nicotine in rats

Pharmacology, biochemistry and behavior, 2010-08, Vol.96 (2), p.217-227

2010

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Attenuating nicotine’s effects with high affinity human anti-nicotine monoclonal antibodies

The relative reinforcing efficacy of nicotine in an adolescent rat model of attention-deficit hyperactivity disorder

Effects of an oxycodone conjugate vaccine on oxycodone self-administration and oxycodone-induced brain gene expression in rats

Cigarette Smoke Extract, but Not Electronic Cigarette Aerosol Extract, Inhibits Monoamine Oxidase in vitro and Produces Greater Acute Aversive/Anhedonic Effects Than Nicotine Alone on Intracranial Self-Stimulation in Rats

Effects of nicotine and minor tobacco alkaloids on intracranial-self-stimulation in rats

Stimulus functions of nicotine

The nicotine-degrading enzyme NicA2 reduces nicotine levels in blood, nicotine distribution to brain, and nicotine discrimination and reinforcement in rats

Substitutability of nicotine and sucrose in rats: A behavioral economic analysis

β-Carbolines found in cigarette smoke elevate intracranial self-stimulation thresholds in rats

New Directions in Nicotine Vaccine Design and Use

The reinforcement threshold for nicotine as a target for tobacco control

The reinforcement threshold and elasticity of demand for nicotine in an adolescent rat model of depression

Propylene glycol, a major electronic cigarette constituent, attenuates the adverse effects of high-dose nicotine as measured by intracranial self-stimulation in rats

Substitutability of nicotine alone and an electronic cigarette liquid using a concurrent choice assay in rats: A behavioral economic analysis

Toward a nonhuman model of contingency management: effects of reinforcing abstinence from nicotine self-administration in rats with an alternative nondrug reinforcer

Non-nicotine constituents in e-cigarette aerosol extract attenuate nicotine’s aversive effects in adolescent rats

Comparison of the Relative Abuse Liability of Electronic Cigarette Aerosol Extracts and Nicotine Alone in Adolescent Rats: A Behavioral Economic Analysis

Restraint stress attenuates nicotine's locomotor stimulant but not discriminative stimulus effects in rats

A lack of association between severity of nicotine withdrawal and individual differences in compensatory nicotine self-administration in rats

Animal models to assess the abuse liability of tobacco products: Effects of smokeless tobacco extracts on intracranial self-stimulation

Delivery of nicotine in an extract of a smokeless tobacco product reduces its reinforcement-attenuating and discriminative stimulus effects in rats

Nicotine reduction revisited: science and future directions

Effects of the nicotinic receptor partial agonists varenicline and cytisine on the discriminative stimulus effects of nicotine in rats

Enhanced attenuation of nicotine discrimination in rats by combining nicotine-specific antibodies with a nicotinic receptor antagonist

Comparison of the behavioral effects of cigarette smoke and pure nicotine in rats

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