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Stem Cell-Derived Neurons as Cellular Models of Sporadic Alzheimer's Disease

Journal of Alzheimer's disease, 2019-01, Vol.67 (3), p.893-910

2019

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Identification of Caspase-6-mediated processing of the valosin containing protein (p97) in Alzheimer's disease: a novel link to dysfunction in ubiquitin proteasome system-mediated protein degradation

The Journal of neuroscience, 2010-04, Vol.30 (17), p.6132-6142

2010

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The Consortium for the early identification of Alzheimer's disease–Quebec (CIMA-Q)

Alzheimer's & dementia : diagnosis, assessment & disease monitoring, 2019-12, Vol.11 (1), p.787-796

2019

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Neuroprotective functions of prion protein

Journal of neuroscience research, 2004-01, Vol.75 (2), p.153-161

2004

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Loss of anti-Bax function in Gerstmann-Sträussler-Scheinker syndrome-associated prion protein mutants

PloS one, 2009-08, Vol.4 (8), p.e6647-e6647

2009

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Natural cellular inhibitors of caspases

Progress in neuro-psychopharmacology & biological psychiatry, 2003-04, Vol.27 (2), p.215-229

LeBlanc, Andréa C

2003

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Caspase-6 as a novel early target in the treatment of Alzheimer's disease

The European journal of neuroscience, 2013-06, Vol.37 (12), p.2005-2018

LeBlanc, Andrea C.

2013

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Sox11 Reduces Caspase-6 Cleavage and Activity

PloS one, 2015-10, Vol.10 (10), p.e0141439

2015

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Caspase-6 Activation in Familial Alzheimer Disease Brains Carrying Amyloid Precursor Protein or Presenilin I or Presenilin II Mutations

Journal of neuropathology and experimental neurology, 2009-12, Vol.68 (12), p.1282-1293

2009

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Caspase-6 activity predicts lower episodic memory ability in aged individuals

Neurobiology of aging, 2013-07, Vol.34 (7), p.1815-1824

2013

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Caspase vinyl sulfone small molecule inhibitors prevent axonal degeneration in human neurons and reverse cognitive impairment in Caspase-6-overexpressing mice

Molecular neurodegeneration, 2017-02, Vol.12 (1), p.22, Article 22

2017

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Methylene blue inhibits Caspase-6 activity, and reverses Caspase-6-induced cognitive impairment and neuroinflammation in aged mice

Acta neuropathologica communications, 2019-12, Vol.7 (1), p.210-210, Article 210

2019

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Caspase-mediated cleavage of actin and tubulin is a common feature and sensitive marker of axonal degeneration in neural development and injury

Acta neuropathologica communications, 2014-02, Vol.2 (1), p.16-16, Article 16

2014

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Cerebrospinal Fluid Tau Cleaved by Caspase-6 Reflects Brain Levels and Cognition in Aging and Alzheimer Disease

Journal of neuropathology and experimental neurology, 2013-09, Vol.72 (9), p.824-832

2013

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Defective Retrotranslocation Causes Loss of Anti-Bax Function in Human Familial Prion Protein Mutants

The Journal of neuroscience, 2007-05, Vol.27 (19), p.5081-5091

2007

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Effect of tumor necrosis factor‐α converting enzyme (TACE) and metalloprotease inhibitor on amyloid precursor protein metabolism in human neurons

Journal of neurochemistry, 2002-12, Vol.83 (6), p.1349-1357

2002

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Helix 3 is necessary and sufficient for prion protein's anti-Bax function

Journal of neurochemistry, 2009-02, Vol.108 (4), p.1019-1031

2009

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Selective and Protracted Apoptosis in Human Primary Neurons Microinjected with Active Caspase-3, -6, -7, and -8

The Journal of neuroscience, 2000-11, Vol.20 (22), p.8384-8389

2000

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Testosterone‐mediated neuroprotection through the androgen receptor in human primary neurons

Journal of neurochemistry, 2001-06, Vol.77 (5), p.1319-1326

2001

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Increased Caspase-6 activity in the human anterior olfactory nuclei of the olfactory bulb is associated with cognitive impairment

Acta neuropathologica communications, 2016-12, Vol.4 (1), p.127-127, Article 127

2016

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Increased production of 4 kDa amyloid beta peptide in serum deprived human primary neuron cultures: possible involvement of apoptosis

The Journal of neuroscience, 1995-12, Vol.15 (12), p.7837-7846

LeBlanc, A

1995

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Telomerase and neuronal marker status of differentiated NT2 and SK-N-SH human neuronal cells and primary human neurons

Journal of neuroscience research, 2007-01, Vol.85 (1), p.83-89

2007

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Amyloid beta Peptide of Alzheimer's Disease Downregulates Bcl-2 and Upregulates Bax Expression in Human Neurons

The Journal of neuroscience, 1996-12, Vol.16 (23), p.7533-7539

1996

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GSK3β is involved in the relief of mitochondria pausing in a Tau-dependent manner

PloS one, 2011-11, Vol.6 (11), p.e27686-e27686

2011

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The P2 receptor antagonist PPADS supports recovery from experimental stroke in vivo

PloS one, 2011-05, Vol.6 (5), p.e19983-e19983

2011

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Stem Cell-Derived Neurons as Cellular Models of Sporadic Alzheimer's Disease

Identification of Caspase-6-mediated processing of the valosin containing protein (p97) in Alzheimer's disease: a novel link to dysfunction in ubiquitin proteasome system-mediated protein degradation

The Consortium for the early identification of Alzheimer's disease–Quebec (CIMA-Q)

Neuroprotective functions of prion protein

Loss of anti-Bax function in Gerstmann-Sträussler-Scheinker syndrome-associated prion protein mutants

Natural cellular inhibitors of caspases

Caspase-6 as a novel early target in the treatment of Alzheimer's disease

Sox11 Reduces Caspase-6 Cleavage and Activity

Caspase-6 Activation in Familial Alzheimer Disease Brains Carrying Amyloid Precursor Protein or Presenilin I or Presenilin II Mutations

Caspase-6 activity predicts lower episodic memory ability in aged individuals

Caspase vinyl sulfone small molecule inhibitors prevent axonal degeneration in human neurons and reverse cognitive impairment in Caspase-6-overexpressing mice

Methylene blue inhibits Caspase-6 activity, and reverses Caspase-6-induced cognitive impairment and neuroinflammation in aged mice

Caspase-mediated cleavage of actin and tubulin is a common feature and sensitive marker of axonal degeneration in neural development and injury

Cerebrospinal Fluid Tau Cleaved by Caspase-6 Reflects Brain Levels and Cognition in Aging and Alzheimer Disease

Defective Retrotranslocation Causes Loss of Anti-Bax Function in Human Familial Prion Protein Mutants

Effect of tumor necrosis factor‐α converting enzyme (TACE) and metalloprotease inhibitor on amyloid precursor protein metabolism in human neurons

Helix 3 is necessary and sufficient for prion protein's anti-Bax function

Selective and Protracted Apoptosis in Human Primary Neurons Microinjected with Active Caspase-3, -6, -7, and -8

Testosterone‐mediated neuroprotection through the androgen receptor in human primary neurons

Increased Caspase-6 activity in the human anterior olfactory nuclei of the olfactory bulb is associated with cognitive impairment

Increased production of 4 kDa amyloid beta peptide in serum deprived human primary neuron cultures: possible involvement of apoptosis

Telomerase and neuronal marker status of differentiated NT2 and SK-N-SH human neuronal cells and primary human neurons

Amyloid beta Peptide of Alzheimer's Disease Downregulates Bcl-2 and Upregulates Bax Expression in Human Neurons

GSK3β is involved in the relief of mitochondria pausing in a Tau-dependent manner

The P2 receptor antagonist PPADS supports recovery from experimental stroke in vivo

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