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SHANK3 overexpression causes manic―like behaviour with unique pharmacogenetic properties

Nature (London), 2013-11, Vol.503 (7474), p.72-77

2013

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Methamphetamine Downregulates Striatal Glutamate Receptors via Diverse Epigenetic Mechanisms

Biological psychiatry (1969), 2014-07, Vol.76 (1), p.47-56

2014

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Valproic acid attenuates blood-brain barrier disruption in a rat model of transient focal cerebral ischemia: the roles of HDAC and MMP-9 inhibition

Journal of cerebral blood flow and metabolism, 2011-01, Vol.31 (1), p.52-57

2011

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The mood stabilizers lithium and valproate selectively activate the promoter IV of brain-derived neurotrophic factor in neurons

Molecular psychiatry, 2009-01, Vol.14 (1), p.51-59

2009

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Idiosyncratic Adverse Reactions to Antiepileptic Drugs

Epilepsia (Copenhagen), 2007-07, Vol.48 (7), p.1223-1244

2007

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Imbalance between pro-inflammatory and anti-inflammatory cytokines in bipolar disorder

Journal of affective disorders, 2007-12, Vol.104 (1), p.91-95

2007

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A new derivative of valproic acid amide possesses a broad-spectrum antiseizure profile and unique activity against status epilepticus and organophosphate neuronal damage

Epilepsia (Copenhagen), 2012-01, Vol.53 (1), p.134-146

2012

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Valproic acid induces functional heat-shock protein 70 via Class I histone deacetylase inhibition in cortical neurons: a potential role of Sp1 acetylation

Journal of neurochemistry, 2009-11, Vol.111 (4), p.976-987

2009

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Valproic acid improves outcome after rodent spinal cord injury: Potential roles of histone deacetylase inhibition

Brain research, 2011-06, Vol.1396, p.60-68

2011

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A comparative electrographic analysis of the effect of sec -butyl-propylacetamide on pharmacoresistant status epilepticus

Neuroscience, 2013-02, Vol.231, p.145-156

2013

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Inhibitors of histone deacetylase (HDAC) restore the p53 pathway in neuroblastoma cells

British journal of pharmacology, 2008-02, Vol.153 (4), p.657-668

2008

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Effect of quercetin and rutin in some acute seizure models in mice

Progress in neuro-psychopharmacology & biological psychiatry, 2014-10, Vol.54, p.50-58

2014

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An in vitro approach to assess the neurotoxicity of valproic acid-induced oxidative stress in cerebellum and cerebral cortex of young rats

Neuroscience, 2012-12, Vol.225, p.258-268

2012

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Pharmacological and therapeutic properties of valproate: A summary after 35 years of clinical experience

CNS drugs, 2002, Vol.16 (10), p.695-714

PERUCCA, Emilio

2002

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Up-regulation of spinal glutamate transporters contributes to anti-hypersensitive effects of valproate in rats after peripheral nerve injury

Neuroscience letters, 2011-09, Vol.502 (1), p.52-55

2011

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Carbamazepine, but not valproate, displays pharmacoresistance in lamotrigine-resistant amygdala kindled rats

Epilepsy research, 2013-03, Vol.104 (1), p.26-34

2013

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Histone deacetylase inhibitors valproic acid and sodium butyrate enhance prostaglandins release in lipopolysaccharide-activated primary microglia

Neuroscience, 2014-04, Vol.265, p.147-157

2014

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Valproic acid and other histone deacetylase inhibitors induce microglial apoptosis and attenuate lipopolysaccharide-induced dopaminergic neurotoxicity

Neuroscience, 2007-10, Vol.149 (1), p.203-212

2007

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Basic pharmacology of valproate: A review after 35 years of clinical use for the treatment of epilepsy

CNS drugs, 2002, Vol.16 (10), p.669-694

Loescher, W

2002

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Synthesis and anticonvulsant evaluation of some new 2,3,8-trisubstituted-4(3H)-quinazoline derivatives

Bioorganic & medicinal chemistry letters, 2012-01, Vol.22 (1), p.327-333

2012

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Protection of dopaminergic cells from MPP+ -mediated toxicity by histone deacetylase inhibition

Brain research, 2010-10, Vol.1354, p.172-178

2010

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The effects of neuropsychiatric drugs on glycogen synthase kinase-3 signaling

Neuroscience, 2011-12, Vol.199, p.116-124

2011

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The Histone Deacetylase Inhibitor Valproic Acid Enhances Acquisition, Extinction, and Reconsolidation of Conditioned Fear

Learning & memory (Cold Spring Harbor, N.Y.), 2008-01, Vol.15 (1), p.39-45

2008

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Anticonvulsant and acute neurotoxic effects of imperatorin, osthole and valproate in the maximal electroshock seizure and chimney tests in mice: A comparative study

Epilepsy research, 2009-08, Vol.85 (2), p.293-299

2009

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Antiepileptic drugs abolish ictal but not interictal epileptiform discharges in vitro

Epilepsia (Copenhagen), 2010-03, Vol.51 (3), p.423-431

2010

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SHANK3 overexpression causes manic―like behaviour with unique pharmacogenetic properties

Methamphetamine Downregulates Striatal Glutamate Receptors via Diverse Epigenetic Mechanisms

Valproic acid attenuates blood-brain barrier disruption in a rat model of transient focal cerebral ischemia: the roles of HDAC and MMP-9 inhibition

The mood stabilizers lithium and valproate selectively activate the promoter IV of brain-derived neurotrophic factor in neurons

Idiosyncratic Adverse Reactions to Antiepileptic Drugs

Imbalance between pro-inflammatory and anti-inflammatory cytokines in bipolar disorder

A new derivative of valproic acid amide possesses a broad-spectrum antiseizure profile and unique activity against status epilepticus and organophosphate neuronal damage

Valproic acid induces functional heat-shock protein 70 via Class I histone deacetylase inhibition in cortical neurons: a potential role of Sp1 acetylation

Valproic acid improves outcome after rodent spinal cord injury: Potential roles of histone deacetylase inhibition

A comparative electrographic analysis of the effect of sec -butyl-propylacetamide on pharmacoresistant status epilepticus

Inhibitors of histone deacetylase (HDAC) restore the p53 pathway in neuroblastoma cells

Effect of quercetin and rutin in some acute seizure models in mice

An in vitro approach to assess the neurotoxicity of valproic acid-induced oxidative stress in cerebellum and cerebral cortex of young rats

Pharmacological and therapeutic properties of valproate: A summary after 35 years of clinical experience

Up-regulation of spinal glutamate transporters contributes to anti-hypersensitive effects of valproate in rats after peripheral nerve injury

Carbamazepine, but not valproate, displays pharmacoresistance in lamotrigine-resistant amygdala kindled rats

Histone deacetylase inhibitors valproic acid and sodium butyrate enhance prostaglandins release in lipopolysaccharide-activated primary microglia

Valproic acid and other histone deacetylase inhibitors induce microglial apoptosis and attenuate lipopolysaccharide-induced dopaminergic neurotoxicity

Basic pharmacology of valproate: A review after 35 years of clinical use for the treatment of epilepsy

Synthesis and anticonvulsant evaluation of some new 2,3,8-trisubstituted-4(3H)-quinazoline derivatives

Protection of dopaminergic cells from MPP+ -mediated toxicity by histone deacetylase inhibition

The effects of neuropsychiatric drugs on glycogen synthase kinase-3 signaling

The Histone Deacetylase Inhibitor Valproic Acid Enhances Acquisition, Extinction, and Reconsolidation of Conditioned Fear

Anticonvulsant and acute neurotoxic effects of imperatorin, osthole and valproate in the maximal electroshock seizure and chimney tests in mice: A comparative study

Antiepileptic drugs abolish ictal but not interictal epileptiform discharges in vitro

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