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The host-cell restriction factor SERINC5 restricts HIV-1 infectivity without altering the lipid composition and organization of viral particles

The Journal of biological chemistry, 2017-08, Vol.292 (33), p.13702-13713

2017

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Beyond Impairment of Virion Infectivity: New Activities of the Anti-HIV Host Cell Factor SERINC5

Viruses, 2024-02, Vol.16 (2), p.284

2024

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Nef Proteins of Epidemic HIV-1 Group O Strains Antagonize Human Tetherin

Cell host & microbe, 2014-11, Vol.16 (5), p.639-650

2014

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HIV-1 Nef and Vpu are functionally redundant broad-spectrum modulators of cell surface receptors, including tetraspanins

Journal of virology, 2014-12, Vol.88 (24), p.14241-14257

2014

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Spotlight on HIV-1 Nef: SERINC3 and SERINC5 Identified as Restriction Factors Antagonized by the Pathogenesis Factor

Viruses, 2015-12, Vol.7 (12), p.6730-6738

Fackler, Oliver T

2015

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HIV-1 Nef interferes with T-lymphocyte circulation through confined environments in vivo

Proceedings of the National Academy of Sciences - PNAS, 2012-11, Vol.109 (45), p.18541-18546

2012

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HIV-1 Nef compensates for disorganization of the immunological synapse by inducing trans-Golgi network–associated Lck signaling

Blood, 2012-01, Vol.119 (3), p.786-797

2012

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Lentiviral Nef Proteins Utilize PAK2-Mediated Deregulation of Cofilin as a General Strategy To Interfere with Actin Remodeling

Journal of Virology, 2010-04, Vol.84 (8), p.3935-3948

2010

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Molecular design, functional characterization and structural basis of a protein inhibitor against the HIV-1 pathogenicity factor Nef

PloS one, 2011-05, Vol.6 (5), p.e20033-e20033

2011

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Association with PAK2 Enables Functional Interactions of Lentiviral Nef Proteins with the Exocyst Complex

mBio, 2015-09, Vol.6 (5), p.e01309-e01315

2015

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Inhibition of the Nef regulatory protein of HIV-1 by a single-domain antibody

Blood, 2011-03, Vol.117 (13), p.3559-3568

2011

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Reacquisition of Nef-Mediated Tetherin Antagonism in a Single In Vivo Passage of HIV-1 through Its Original Chimpanzee Host

Cell host & microbe, 2012-09, Vol.12 (3), p.373-380

2012

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HIV Nef- and Notch1-dependent Endocytosis of ADAM17 Induces Vesicular TNF Secretion in Chronic HIV Infection

EBioMedicine, 2016-11, Vol.13 (C), p.294-304

2016

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Heterologous Src Homology 4 Domains Support Membrane Anchoring and Biological Activity of HIV-1 Nef

The Journal of biological chemistry, 2014-05, Vol.289 (20), p.14030-14044

2014

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HIV‐1 Nef disrupts membrane‐microdomain‐associated anterograde transport for plasma membrane delivery of selected Src family kinases

Cellular microbiology, 2013-10, Vol.15 (10), p.1605-1621

2013

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The identification of a small molecule compound that reduces HIV-1 Nef-mediated viral infectivity enhancement

PloS one, 2011-11, Vol.6 (11), p.e27696-e27696

2011

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Human immunodeficiency virus type 1 Nef protein modulates the lipid composition of virions and host cell membrane microdomains

Retrovirology, 2007-10, Vol.4 (1), p.70-70, Article 70

2007

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SERINC5 Can Enhance Proinflammatory Cytokine Production by Primary Human Myeloid Cells in Response to Challenge with HIV-1 Particles

Journal of virology, 2021-04, Vol.95 (9)

2021

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Identification of a highly conserved valine-glycine-phenylalanine amino acid triplet required for HIV-1 Nef function

Retrovirology, 2012-04, Vol.9 (1), p.34-34, Article 34

2012

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Intrinsic properties and plasma membrane trafficking route of Src family kinase SH4 domains sensitive to retargeting by HIV-1 Nef

The Journal of biological chemistry, 2018-05, Vol.293 (20), p.7824-7840

2018

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HIV-1 Nef limits communication between linker of activated T cells and SLP-76 to reduce formation of SLP-76-signaling microclusters following TCR stimulation

The Journal of immunology (1950), 2012-08, Vol.189 (4), p.1898-1910

2012

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D186/D190 is an allele-dependent determinant of HIV-1 Nef function

Virology (New York, N.Y.), 2016-11, Vol.498, p.44-56

2016

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Nef does not inhibit F-actin remodelling and HIV-1 cell–cell transmission at the T lymphocyte virological synapse

European journal of cell biology, 2011-11, Vol.90 (11), p.913-921

2011

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HIV-1 Nef Perturbs Artificial Membranes: Investigation of the Contribution of the Myristoyl Anchor

Biophysical journal, 2009-04, Vol.96 (8), p.3242-3250

2009

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Primate lentiviral Nef proteins deregulate T-cell development by multiple mechanisms

Retrovirology, 2013-11, Vol.10 (1), p.137-137, Article 137

2013

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The host-cell restriction factor SERINC5 restricts HIV-1 infectivity without altering the lipid composition and organization of viral particles

Beyond Impairment of Virion Infectivity: New Activities of the Anti-HIV Host Cell Factor SERINC5

Nef Proteins of Epidemic HIV-1 Group O Strains Antagonize Human Tetherin

HIV-1 Nef and Vpu are functionally redundant broad-spectrum modulators of cell surface receptors, including tetraspanins

Spotlight on HIV-1 Nef: SERINC3 and SERINC5 Identified as Restriction Factors Antagonized by the Pathogenesis Factor

HIV-1 Nef interferes with T-lymphocyte circulation through confined environments in vivo

HIV-1 Nef compensates for disorganization of the immunological synapse by inducing trans-Golgi network–associated Lck signaling

Lentiviral Nef Proteins Utilize PAK2-Mediated Deregulation of Cofilin as a General Strategy To Interfere with Actin Remodeling

Molecular design, functional characterization and structural basis of a protein inhibitor against the HIV-1 pathogenicity factor Nef

Association with PAK2 Enables Functional Interactions of Lentiviral Nef Proteins with the Exocyst Complex

Inhibition of the Nef regulatory protein of HIV-1 by a single-domain antibody

Reacquisition of Nef-Mediated Tetherin Antagonism in a Single In Vivo Passage of HIV-1 through Its Original Chimpanzee Host

HIV Nef- and Notch1-dependent Endocytosis of ADAM17 Induces Vesicular TNF Secretion in Chronic HIV Infection

Heterologous Src Homology 4 Domains Support Membrane Anchoring and Biological Activity of HIV-1 Nef

HIV‐1 Nef disrupts membrane‐microdomain‐associated anterograde transport for plasma membrane delivery of selected Src family kinases

The identification of a small molecule compound that reduces HIV-1 Nef-mediated viral infectivity enhancement

Human immunodeficiency virus type 1 Nef protein modulates the lipid composition of virions and host cell membrane microdomains

SERINC5 Can Enhance Proinflammatory Cytokine Production by Primary Human Myeloid Cells in Response to Challenge with HIV-1 Particles

Identification of a highly conserved valine-glycine-phenylalanine amino acid triplet required for HIV-1 Nef function

Intrinsic properties and plasma membrane trafficking route of Src family kinase SH4 domains sensitive to retargeting by HIV-1 Nef

HIV-1 Nef limits communication between linker of activated T cells and SLP-76 to reduce formation of SLP-76-signaling microclusters following TCR stimulation

D186/D190 is an allele-dependent determinant of HIV-1 Nef function

Nef does not inhibit F-actin remodelling and HIV-1 cell–cell transmission at the T lymphocyte virological synapse

HIV-1 Nef Perturbs Artificial Membranes: Investigation of the Contribution of the Myristoyl Anchor

Primate lentiviral Nef proteins deregulate T-cell development by multiple mechanisms

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