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Engineering human ACE2 to optimize binding to the spike protein of SARS coronavirus 2

Science (American Association for the Advancement of Science), 2020-09, Vol.369 (6508), p.1261-1265

2020

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An Engineered Switch in T Cell Receptor Specificity Leads to an Unusual but Functional Binding Geometry

Structure (London), 2016-07, Vol.24 (7), p.1142-1154

2016

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Rapid Response to Cyclosporin A and Favorable Renal Outcome in Nongenetic Versus Genetic Steroid-Resistant Nephrotic Syndrome

Clinical journal of the American Society of Nephrology, 2016-02, Vol.11 (2), p.245-253

2016

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Genetic variation at the 8q24.21 renal cancer susceptibility locus affects HIF binding to a MYC enhancer

Nature communications, 2016-10, Vol.7 (1), p.13183-13183, Article 13183

2016

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Immunosuppression and Renal Outcome in Congenital and Pediatric Steroid-Resistant Nephrotic Syndrome

Clinical journal of the American Society of Nephrology, 2010-11, Vol.5 (11), p.2075-2084

2010

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Directed evolution of a stable scaffold for T-cell receptor engineering

Nature biotechnology, 2000-07, Vol.18 (7), p.754-759

2000

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Class II-Restricted T Cell Receptor Engineered in vitro for Higher Affinity Retains Peptide Specificity and Function

Proceedings of the National Academy of Sciences - PNAS, 2005-12, Vol.102 (52), p.19033-19038

2005

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In vitro Evolution of a T Cell Receptor with High Affinity for Peptide/MHC

Proceedings of the National Academy of Sciences - PNAS, 2000-05, Vol.97 (10), p.5387-5392

2000

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TCR-engineered adoptive cell therapy effectively treats intracranial murine glioblastoma

Journal for immunotherapy of cancer, 2023-02, Vol.11 (2), p.e006121

2023

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Changing the peptide specificity of a human T-cell receptor by directed evolution

Nature communications, 2014-11, Vol.5 (1), p.5223-5223, Article 5223

2014

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Loss of tubulin deglutamylase CCP1 causes infantile‐onset neurodegeneration

The EMBO journal, 2018-12, Vol.37 (23), p.n/a

2018

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Long-Range Cooperative Binding Effects in a T Cell Receptor Variable Domain

Proceedings of the National Academy of Sciences - PNAS, 2006-06, Vol.103 (26), p.9867-9872

2006

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A kinome-wide RNAi screen identifies ALK as a target to sensitize neuroblastoma cells for HDAC8-inhibitor treatment

Cell death and differentiation, 2018-12, Vol.25 (12), p.2053-2070

2018

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Selection of Functional T Cell Receptor Mutants from a Yeast Surface-Display Library

Proceedings of the National Academy of Sciences - PNAS, 1999-05, Vol.96 (10), p.5651-5656

1999

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Yeast polypeptide fusion surface display levels predict thermal stability and soluble secretion efficiency

Journal of molecular biology, 1999-10, Vol.292 (5), p.949-956

1999

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Different Thermodynamic Binding Mechanisms and Peptide Fine Specificities Associated with a Panel of Structurally Similar High-Affinity T Cell Receptors

Biochemistry (Easton), 2008-11, Vol.47 (47), p.12398-12408

2008

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Polyhydroxyalkanoate production in Rhodobacter capsulatus: genes, mutants, expression, and physiology

Applied and Environmental Microbiology, 1997-08, Vol.63 (8), p.3003-3009

1997

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The temperature-sensitive growth and survival phenotypes of Escherichia coli cydDC and cydAB strains are due to deficiencies in cytochrome bd and are corrected by exogenous catalase and reducing agents

Journal of Bacteriology, 1996-11, Vol.178 (21), p.6348-6351

1996

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High-affinity T cell receptor differentiates cognate peptide–MHC and altered peptide ligands with distinct kinetics and thermodynamics

Molecular immunology, 2010-05, Vol.47 (9), p.1793-1801

2010

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Urinary tract effects of HPSE2 mutations

Journal of the American Society of Nephrology, 2015-04, Vol.26 (4), p.797-804

2015

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Use of heme reporters for studies of cytochrome biosynthesis and heme transport

Journal of Bacteriology, 1996-11, Vol.178 (21), p.6338-6347

1996

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A homozygous ZMPSTE24 null mutation in combination with a heterozygous mutation in the LMNA gene causes Hutchinson-Gilford progeria syndrome (HGPS): insights into the pathophysiology of HGPS

Human mutation, 2006-06, Vol.27 (6), p.524-531

2006

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Development of a novel strategy for engineering high-affinity proteins by yeast display

Protein engineering, design and selection, 2006-06, Vol.19 (6), p.255-264

2006

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Overexpression of ccl1−2 can bypass the need for the putative apocytochrome chaperone CycH during the biogenesis of c‐type cytochromes

Molecular microbiology, 2002-11, Vol.46 (4), p.1069-1080

2002

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Merkel cell polyomavirus (MCV) T-antigen seroreactivity, MCV DNA in eyebrow hairs, and squamous cell carcinoma

Infectious agents and cancer, 2015-10, Vol.10 (1), p.35-35, Article 35

2015

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Engineering human ACE2 to optimize binding to the spike protein of SARS coronavirus 2

An Engineered Switch in T Cell Receptor Specificity Leads to an Unusual but Functional Binding Geometry

Rapid Response to Cyclosporin A and Favorable Renal Outcome in Nongenetic Versus Genetic Steroid-Resistant Nephrotic Syndrome

Genetic variation at the 8q24.21 renal cancer susceptibility locus affects HIF binding to a MYC enhancer

Immunosuppression and Renal Outcome in Congenital and Pediatric Steroid-Resistant Nephrotic Syndrome

Directed evolution of a stable scaffold for T-cell receptor engineering

Class II-Restricted T Cell Receptor Engineered in vitro for Higher Affinity Retains Peptide Specificity and Function

In vitro Evolution of a T Cell Receptor with High Affinity for Peptide/MHC

TCR-engineered adoptive cell therapy effectively treats intracranial murine glioblastoma

Changing the peptide specificity of a human T-cell receptor by directed evolution

Loss of tubulin deglutamylase CCP1 causes infantile‐onset neurodegeneration

Long-Range Cooperative Binding Effects in a T Cell Receptor Variable Domain

A kinome-wide RNAi screen identifies ALK as a target to sensitize neuroblastoma cells for HDAC8-inhibitor treatment

Selection of Functional T Cell Receptor Mutants from a Yeast Surface-Display Library

Yeast polypeptide fusion surface display levels predict thermal stability and soluble secretion efficiency

Different Thermodynamic Binding Mechanisms and Peptide Fine Specificities Associated with a Panel of Structurally Similar High-Affinity T Cell Receptors

Polyhydroxyalkanoate production in Rhodobacter capsulatus: genes, mutants, expression, and physiology

The temperature-sensitive growth and survival phenotypes of Escherichia coli cydDC and cydAB strains are due to deficiencies in cytochrome bd and are corrected by exogenous catalase and reducing agents

High-affinity T cell receptor differentiates cognate peptide–MHC and altered peptide ligands with distinct kinetics and thermodynamics

Urinary tract effects of HPSE2 mutations

Use of heme reporters for studies of cytochrome biosynthesis and heme transport

A homozygous ZMPSTE24 null mutation in combination with a heterozygous mutation in the LMNA gene causes Hutchinson-Gilford progeria syndrome (HGPS): insights into the pathophysiology of HGPS

Development of a novel strategy for engineering high-affinity proteins by yeast display

Overexpression of ccl1−2 can bypass the need for the putative apocytochrome chaperone CycH during the biogenesis of c‐type cytochromes

Merkel cell polyomavirus (MCV) T-antigen seroreactivity, MCV DNA in eyebrow hairs, and squamous cell carcinoma

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