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Biological diversity and therapeutic potential of natural and engineered cystine knot miniproteins

Current opinion in pharmacology, 2009-10, Vol.9 (5), p.608-614

Kolmar, Harald

2009

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Natural and engineered cystine knot miniproteins for diagnostic and therapeutic applications

Current pharmaceutical design, 2011-12, Vol.17 (38), p.4329-4336

Kolmar, Harald

2011

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Bi-specific Aptamers Mediating Tumor Cell Lysis

The Journal of biological chemistry, 2011-06, Vol.286 (24), p.21896-21905

2011

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Chemical synthesis, backbone cyclization and oxidative folding of cystine-knot peptides: promising scaffolds for applications in drug design

Molecules, 2012-10, Vol.17 (11), p.12533-12552

2012

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Fragmentation follows structure: top-down mass spectrometry elucidates the topology of engineered cystine-knot miniproteins

PloS one, 2014-10, Vol.9 (10), p.e108626-e108626

2014

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DNA libraries for the construction of phage libraries: statistical and structural requirements and synthetic methods

Molecules, 2011-02, Vol.16 (2), p.1625-1641

2011

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The crystal structure of SdsA1, an alkylsulfatase from Pseudomonas aeruginosa, defines a third class of sulfatases

Proceedings of the National Academy of Sciences - PNAS, 2006-05, Vol.103 (20), p.7631-7636

2006

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A generic system for the Escherichia coli cell-surface display of lipolytic enzymes

FEBS letters, 2005-02, Vol.579 (5), p.1177-1182

2005

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Engineered cystine-knot miniproteins for diagnostic applications

Expert review of molecular diagnostics, 2010-04, Vol.10 (3), p.361-368

Kolmar, Harald

2010

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The potential of cystine-knot microproteins as novel pharmacophoric scaffolds in oral peptide drug delivery

Journal of drug targeting, 2006-01, Vol.14 (3), p.137-146

2006

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Trypsin inhibition by macrocyclic and open-chain variants of the squash inhibitor MCoTI-II

Biological chemistry, 2005-12, Vol.386 (12), p.1301-1306

2005

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Engineered Cystine Knot Miniproteins as Potent Inhibitors of Human Mast Cell Tryptase β

Journal of molecular biology, 2010-01, Vol.395 (1), p.167-175

2010

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Oxidative Folding of Peptides with Cystine-Knot Architectures: Kinetic Studies and Optimization of Folding Conditions

Chembiochem : a European journal of chemical biology, 2013-01, Vol.14 (1), p.137-146

2013

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From pico to nano: biofunctionalization of cube-octameric silsesquioxanes by peptides and miniproteins

Organic & biomolecular chemistry, 2012-08, Vol.10 (31), p.6287-6293

2012

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Dimerisation of the glycophorin A transmembrane segment in membranes probed with the ToxR transcription activator

Journal of molecular biology, 1996-11, Vol.263 (4), p.525-530

1996

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Display of passenger proteins on the surface of Escherichia coli K-12 by the enterohemorrhagic E. coli intimin EaeA

Journal of bacteriology, 2001-12, Vol.183 (24), p.7273-7284

2001

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Sunflower Trypsin Inhibitor 1 Derivatives as Molecular Scaffolds for the Development of Novel Peptidic Radiopharmaceuticals

Molecular imaging and biology, 2010-08, Vol.12 (4), p.377-385

2010

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Head-to-Tail Cyclized Cystine-Knot Peptides by a Combined Recombinant and Chemical Route of Synthesis

Chembiochem : a European journal of chemical biology, 2008-01, Vol.9 (1), p.33-37

2008

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Microbodies

Methods in molecular biology (Clifton, N.J.), 2009, Vol.535, p.361

2009

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Epitope mapping and affinity purification of monospecific antibodies by Escherichia coli cell surface display of gene-derived random peptide libraries

Journal of immunological methods, 2001-11, Vol.257 (1), p.163-173

2001

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The cystine knot of a squash-type protease inhibitor as a structural scaffold for Escherichia coli cell surface display of conformationally constrained peptides

Protein engineering, 1999-09, Vol.12 (9), p.797-806

1999

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A fusion protein system for the recombinant production of short disulfide bond rich cystine knot peptides using barnase as a purification handle

Protein expression and purification, 2005, Vol.39 (1), p.82-89

2005

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The DegP and DegQ periplasmic endoproteases of Escherichia coli: specificity for cleavage sites and substrate conformation

Journal of Bacteriology, 1996-10, Vol.178 (20), p.5925-5929

1996

Volltextzugriff (PDF)

Barnase Fusion as a Tool to Determine the Crystal Structure of the Small Disulfide-rich Protein McoEeTI

Journal of molecular biology, 2006-02, Vol.356 (1), p.1-8

2006

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The vsr gene product of E. coli K-12 is a strand- and sequence-specific DNA mismatch endonuclease

Nature (London), 1991-10, Vol.353 (6346), p.776-778

1991

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Biological diversity and therapeutic potential of natural and engineered cystine knot miniproteins

Natural and engineered cystine knot miniproteins for diagnostic and therapeutic applications

Bi-specific Aptamers Mediating Tumor Cell Lysis

Chemical synthesis, backbone cyclization and oxidative folding of cystine-knot peptides: promising scaffolds for applications in drug design

Fragmentation follows structure: top-down mass spectrometry elucidates the topology of engineered cystine-knot miniproteins

DNA libraries for the construction of phage libraries: statistical and structural requirements and synthetic methods

The crystal structure of SdsA1, an alkylsulfatase from Pseudomonas aeruginosa, defines a third class of sulfatases

A generic system for the Escherichia coli cell-surface display of lipolytic enzymes

Engineered cystine-knot miniproteins for diagnostic applications

The potential of cystine-knot microproteins as novel pharmacophoric scaffolds in oral peptide drug delivery

Trypsin inhibition by macrocyclic and open-chain variants of the squash inhibitor MCoTI-II

Engineered Cystine Knot Miniproteins as Potent Inhibitors of Human Mast Cell Tryptase β

Oxidative Folding of Peptides with Cystine-Knot Architectures: Kinetic Studies and Optimization of Folding Conditions

From pico to nano: biofunctionalization of cube-octameric silsesquioxanes by peptides and miniproteins

Dimerisation of the glycophorin A transmembrane segment in membranes probed with the ToxR transcription activator

Display of passenger proteins on the surface of Escherichia coli K-12 by the enterohemorrhagic E. coli intimin EaeA

Sunflower Trypsin Inhibitor 1 Derivatives as Molecular Scaffolds for the Development of Novel Peptidic Radiopharmaceuticals

Head-to-Tail Cyclized Cystine-Knot Peptides by a Combined Recombinant and Chemical Route of Synthesis

Microbodies

Epitope mapping and affinity purification of monospecific antibodies by Escherichia coli cell surface display of gene-derived random peptide libraries

The cystine knot of a squash-type protease inhibitor as a structural scaffold for Escherichia coli cell surface display of conformationally constrained peptides

A fusion protein system for the recombinant production of short disulfide bond rich cystine knot peptides using barnase as a purification handle

The DegP and DegQ periplasmic endoproteases of Escherichia coli: specificity for cleavage sites and substrate conformation

Barnase Fusion as a Tool to Determine the Crystal Structure of the Small Disulfide-rich Protein McoEeTI

The vsr gene product of E. coli K-12 is a strand- and sequence-specific DNA mismatch endonuclease

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