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Sequential Metabolism and Bioactivation of the Hepatotoxin Benzbromarone: Formation of Glutathione Adducts From a Catechol Intermediate

Chemical research in toxicology, 2007-12, Vol.20 (12), p.1833-1842

2007

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Human hepatic flavin-containing monooxygenases 1 (FMO1) and 3 (FMO3) developmental expression

Pediatric research, 2002-02, Vol.51 (2), p.236-243

2002

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Cytochrome P450-Dependent Catabolism of Vitamin K: ω‑Hydroxylation Catalyzed by Human CYP4F2 and CYP4F11

Biochemistry (Easton), 2013-11, Vol.52 (46), p.8276-8285

2013

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Involvement of human cytochrome P450 2D6 in the bioactivation of acetaminophen

Drug metabolism and disposition, 2000-12, Vol.28 (12), p.1397

2000

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In vitro evaluation of potential in vivo probes for human flavin‐containing monooxygenase (FMO): metabolism of benzydamine and caffeine by FMO and P450 isoforms

British journal of clinical pharmacology, 2000-10, Vol.50 (4), p.311-314

2000

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Functional analysis of human microsomal epoxide hydrolase genetic variants

Chemico-biological interactions, 2004-11, Vol.150 (2), p.149-159

2004

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Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin-drug interactions

Chemical research in toxicology, 1992-01, Vol.5 (1), p.54-59

1992

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Mechanism-Based Inactivation of Human Cytochrome P450 1A2 by Furafylline: Detection of a 1:1 Adduct to Protein and Evidence for the Formation of a Novel Imidazomethide Intermediate

Biochemistry (Easton), 1998-05, Vol.37 (20), p.7407-7419

1998

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Flunitrazepam metabolism by cytochrome P450S 2C19 and 3A4

Drug metabolism and disposition, 2001-04, Vol.29 (4 Pt 1), p.460

2001

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Identification of Enzymes Involved in the Metabolism of Atrazine, Terbuthylazine, Ametryne, and Terbutryne in Human Liver Microsomes

Chemical research in toxicology, 1997-09, Vol.10 (9), p.1037-1044

1997

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Immunoquantitation of FMO1 in human liver, kidney, and intestine

Drug metabolism and disposition, 2000-09, Vol.28 (9), p.1107

2000

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Alternative Splicing Determines the Function of CYP4F3 by Switching Substrate Specificity

The Journal of biological chemistry, 2001-10, Vol.276 (41), p.38166-38172

2001

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Metabolism of sulfinpyrazone sulfide and sulfinpyrazone by human liver microsomes and cDNA-expressed cytochrome P450s

Drug metabolism and disposition, 2001-05, Vol.29 (5), p.701

2001

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Cytochrome P450-dependent desaturation of lauric acid: isoform selectivity and mechanism of formation of 11-dodecenoic acid

Chemico-biological interactions, 1998-03, Vol.110 (1), p.103-121

1998

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(+)-N-3-Benzyl-nirvanol and (-)-N-3-benzyl-phenobarbital: new potent and selective in vitro inhibitors of CYP2C19

Drug metabolism and disposition, 2002-03, Vol.30 (3), p.235

2002

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Mechanism-based inactivation of human liver cytochrome P450 2A6 by 8-methoxypsoralen

Drug metabolism and disposition, 1997-12, Vol.25 (12), p.1407

1997

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Stereoselective sulfoxidation of sulindac sulfide by flavin-containing monooxygenases: Comparison of human liver and kidney microsomes and mammalian enzymes

Biochemical pharmacology, 2000-07, Vol.60 (1), p.7-17

2000

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Selenoxidation by Flavin-Containing Monooxygenases as a Novel Pathway for β-Elimination of Selenocysteine Se-Conjugates

Chemical research in toxicology, 2001-01, Vol.14 (1), p.127-134

2001

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N-oxygenation of clozapine by flavin-containing monooxygenase

Drug metabolism and disposition, 1997-04, Vol.25 (4), p.524

1997

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Isoform specificity of trimethylamine N-oxygenation by human flavin-containing monooxygenase (FMO) and P450 enzymes : Selective catalysis by fmo3

Biochemical pharmacology, 1998-10, Vol.56 (8), p.1005-1012

1998

Volltextzugriff (PDF)

Inhibition of human liver microsomal epoxide hydrolase by valproate and valpromide: In vitro in vivo correlation

Clinical pharmacology and therapeutics, 1989-07, Vol.46 (1), p.82-93

1989

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Three-dimensional quantitative structure-activity relationship for inhibitors of cytochrome P4502C9

Drug metabolism and disposition, 1996-01, Vol.24 (1), p.1

1996

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Formation of (R)-8-hydroxywarfarin in human liver microsomes. A new metabolic marker for the (S)-mephenytoin hydroxylase, P4502C19

Drug metabolism and disposition, 1996-05, Vol.24 (5), p.610

1996

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Prochiral Sulfoxidation as a Probe for Multiple Forms of the Microsomal Flavin-Containing Monooxygenase: Studies with Rabbit FMO1, FMO2, FMO3, and FMO5 Expressed in Escherichia coli

Archives of biochemistry and biophysics, 1994-06, Vol.311 (2), p.369-377

1994

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Prochiral sulfides as in vitro probes for multiple forms of the flavin-containing monooxygenase

Chemico-biological interactions, 1995-04, Vol.96 (1), p.3-15

1995

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Sequential Metabolism and Bioactivation of the Hepatotoxin Benzbromarone: Formation of Glutathione Adducts From a Catechol Intermediate

Human hepatic flavin-containing monooxygenases 1 (FMO1) and 3 (FMO3) developmental expression

Cytochrome P450-Dependent Catabolism of Vitamin K: ω‑Hydroxylation Catalyzed by Human CYP4F2 and CYP4F11

Involvement of human cytochrome P450 2D6 in the bioactivation of acetaminophen

In vitro evaluation of potential in vivo probes for human flavin‐containing monooxygenase (FMO): metabolism of benzydamine and caffeine by FMO and P450 isoforms

Functional analysis of human microsomal epoxide hydrolase genetic variants

Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin-drug interactions

Mechanism-Based Inactivation of Human Cytochrome P450 1A2 by Furafylline: Detection of a 1:1 Adduct to Protein and Evidence for the Formation of a Novel Imidazomethide Intermediate

Flunitrazepam metabolism by cytochrome P450S 2C19 and 3A4

Identification of Enzymes Involved in the Metabolism of Atrazine, Terbuthylazine, Ametryne, and Terbutryne in Human Liver Microsomes

Immunoquantitation of FMO1 in human liver, kidney, and intestine

Alternative Splicing Determines the Function of CYP4F3 by Switching Substrate Specificity

Metabolism of sulfinpyrazone sulfide and sulfinpyrazone by human liver microsomes and cDNA-expressed cytochrome P450s

Cytochrome P450-dependent desaturation of lauric acid: isoform selectivity and mechanism of formation of 11-dodecenoic acid

(+)-N-3-Benzyl-nirvanol and (-)-N-3-benzyl-phenobarbital: new potent and selective in vitro inhibitors of CYP2C19

Mechanism-based inactivation of human liver cytochrome P450 2A6 by 8-methoxypsoralen

Stereoselective sulfoxidation of sulindac sulfide by flavin-containing monooxygenases: Comparison of human liver and kidney microsomes and mammalian enzymes

Selenoxidation by Flavin-Containing Monooxygenases as a Novel Pathway for β-Elimination of Selenocysteine Se-Conjugates

N-oxygenation of clozapine by flavin-containing monooxygenase

Isoform specificity of trimethylamine N-oxygenation by human flavin-containing monooxygenase (FMO) and P450 enzymes : Selective catalysis by fmo3

Inhibition of human liver microsomal epoxide hydrolase by valproate and valpromide: In vitro in vivo correlation

Three-dimensional quantitative structure-activity relationship for inhibitors of cytochrome P4502C9

Formation of (R)-8-hydroxywarfarin in human liver microsomes. A new metabolic marker for the (S)-mephenytoin hydroxylase, P4502C19

Prochiral Sulfoxidation as a Probe for Multiple Forms of the Microsomal Flavin-Containing Monooxygenase: Studies with Rabbit FMO1, FMO2, FMO3, and FMO5 Expressed in Escherichia coli

Prochiral sulfides as in vitro probes for multiple forms of the flavin-containing monooxygenase

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