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Characterization of metabolites and cytochrome P450 isoforms involved in the microsomal metabolism of aconitine

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2006-12, Vol.844 (2), p.292-300

2006

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Inhibitory effects of a dietary phytochemical 3,3′-diindolylmethane on the phenobarbital-induced hepatic CYP mRNA expression and CYP-catalyzed reactions in female rats

Food and chemical toxicology, 2008-07, Vol.46 (7), p.2451-2458

2008

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Sex differences in subacute toxicity and hepatic microsomal metabolism of triptolide in rats

Toxicology (Amsterdam), 2010-04, Vol.271 (1), p.57-63

2010

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Age-related changes in hepatic expression and activity of cytochrome P450 in male rats

Archives of toxicology, 2010-12, Vol.84 (12), p.939-946

2010

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Impacts of Blast-Induced Traumatic Brain Injury on Expressions of Hepatic Cytochrome P450 1A2, 2B1, 2D1, and 3A2 in Rats

Cellular and molecular neurobiology, 2017-01, Vol.37 (1), p.111-120

2017

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Effects of Sublethal Exposure to a Glyphosate-Based Herbicide Formulation on Metabolic Activities of Different Xenobiotic-Metabolizing Enzymes in Rats

International journal of toxicology, 2014-07, Vol.33 (4), p.307-318

2014

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A mechanism-based integrated pharmacokinetic enzyme model describing the time course and magnitude of phenobarbital-mediated enzyme induction in the rat

Pharmaceutical research, 2006-03, Vol.23 (3), p.521-532

2006

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Effects of short-term in vivo exposure to polybrominated diphenyl ethers on thyroid hormones and hepatic enzyme activities in weanling rats

Toxicological sciences, 2001-05, Vol.61 (1), p.76-82

2001

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Reduction of thyroid hormones triggers down-regulation of hepatic CYP2B through nuclear receptors CAR and TR in a rat model of acute stroke

Biochemical pharmacology, 2014-02, Vol.87 (4), p.636-649

2014

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Mode of Action Analysis for the Synthetic Pyrethroid Metofluthrin-Induced Rat Liver Tumors: Evidence for Hepatic CYP2B Induction and Hepatocyte Proliferation

Toxicological sciences, 2009-03, Vol.108 (1), p.69-80

2009

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Bupropion hydroxylation as a selective marker of rat CYP2B1 catalytic activity

Drug metabolism and disposition, 2012-01, Vol.40 (1), p.32

2012

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Homology modeling and molecular dynamics of CYP1A1 and CYP2B1 to explore the metabolism of aryl derivatives by docking and experimental assays

European journal of medicinal chemistry, 2010-11, Vol.45 (11), p.4845-4855

2010

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Increased Exposure of Vitamin A by Chrysanthemum morifolium Ramat Extract in Rat Was Not via Induction of CYP1A1, CYP1A2, and CYP2B1

Journal of food science, 2012-06, Vol.77 (6), p.H121-H127

2012

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Mechanistic studies with N-benzyl-1-aminobenzotriazole-inactivated CYP2B1: differential effects on the metabolism of 7-ethoxy-4-(trifluoromethyl)coumarin, testosterone, and benzphetamine

Archives of biochemistry and biophysics, 2004-03, Vol.423 (2), p.277-287

2004

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Changes in expression of hepatic cytochrome P450 subfamily enzymes during development of adjuvant-induced arthritis in rats

The Journal of Toxicological Sciences, 2011/04/01, Vol.36(2), pp.181-190

2011

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In vitro metabolism and covalent binding of ethylbenzene to microsomal protein as a possible mechanism of ethylbenzene-induced mouse lung tumorigenesis

Regulatory toxicology and pharmacology, 2010-07, Vol.57 (2-3), p.129-135

2010

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Conformational Change and Activation of Cytochrome P450 2B1 Induced by Salt and Phospholipid

Archives of biochemistry and biophysics, 1998-08, Vol.356 (2), p.229-238

1998

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Green tea extract increases cyclophosphamide-induced teratogenesis by modulating the expression of cytochrome P-450 mRNA

Reproductive toxicology (Elmsford, N.Y.), 2009, Vol.27 (1), p.79-84

2009

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Structural requirements for inhibitors of cytochromes P450 2B: Assessment of the enzyme interaction with diamondoids

Journal of enzyme inhibition and medicinal chemistry, 2005-02, Vol.20 (1), p.25-33

2005

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Effect of shenfu injection on CYP450s of rat liver

Yao hsüeh hsüeh pao, 2013-05, Vol.48 (5), p.728

2013

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Effects of Matrine and Oxymatrine on Catalytic Activity of Cytochrome P450s in Rats

Basic & clinical pharmacology & toxicology, 2010-11, Vol.107 (5), p.906-913

2010

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Promoting effects of monomethylarsonic acid, dimethylarsinic acid and trimethylarsine oxide on induction of rat liver preneoplastic glutathione S‐transferase placental form positive foci: A possible reactive oxygen species mechanism

International journal of cancer, 2002-07, Vol.100 (2), p.136-139

2002

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Effects of benzyl isothiocyanate on rat and human cytochromes P450: identification of metabolites formed by P450 2B1

The Journal of pharmacology and experimental therapeutics, 2001-01, Vol.296 (1), p.198

2001

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influence of diet composition on phase I and II biotransformation enzyme induction

Archives of toxicology, 2008-12, Vol.82 (12), p.893-901

2008

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Effect of selected antidepressant drugs on cytochrome P450 2B (CYP2B) in rat liver. An in vitro and in vivo study

Pharmacological reports, 2008-11, Vol.60 (6), p.957-965

2008

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Characterization of metabolites and cytochrome P450 isoforms involved in the microsomal metabolism of aconitine

Inhibitory effects of a dietary phytochemical 3,3′-diindolylmethane on the phenobarbital-induced hepatic CYP mRNA expression and CYP-catalyzed reactions in female rats

Sex differences in subacute toxicity and hepatic microsomal metabolism of triptolide in rats

Age-related changes in hepatic expression and activity of cytochrome P450 in male rats

Impacts of Blast-Induced Traumatic Brain Injury on Expressions of Hepatic Cytochrome P450 1A2, 2B1, 2D1, and 3A2 in Rats

Effects of Sublethal Exposure to a Glyphosate-Based Herbicide Formulation on Metabolic Activities of Different Xenobiotic-Metabolizing Enzymes in Rats

A mechanism-based integrated pharmacokinetic enzyme model describing the time course and magnitude of phenobarbital-mediated enzyme induction in the rat

Effects of short-term in vivo exposure to polybrominated diphenyl ethers on thyroid hormones and hepatic enzyme activities in weanling rats

Reduction of thyroid hormones triggers down-regulation of hepatic CYP2B through nuclear receptors CAR and TR in a rat model of acute stroke

Mode of Action Analysis for the Synthetic Pyrethroid Metofluthrin-Induced Rat Liver Tumors: Evidence for Hepatic CYP2B Induction and Hepatocyte Proliferation

Bupropion hydroxylation as a selective marker of rat CYP2B1 catalytic activity

Homology modeling and molecular dynamics of CYP1A1 and CYP2B1 to explore the metabolism of aryl derivatives by docking and experimental assays

Increased Exposure of Vitamin A by Chrysanthemum morifolium Ramat Extract in Rat Was Not via Induction of CYP1A1, CYP1A2, and CYP2B1

Mechanistic studies with N-benzyl-1-aminobenzotriazole-inactivated CYP2B1: differential effects on the metabolism of 7-ethoxy-4-(trifluoromethyl)coumarin, testosterone, and benzphetamine

Changes in expression of hepatic cytochrome P450 subfamily enzymes during development of adjuvant-induced arthritis in rats

In vitro metabolism and covalent binding of ethylbenzene to microsomal protein as a possible mechanism of ethylbenzene-induced mouse lung tumorigenesis

Conformational Change and Activation of Cytochrome P450 2B1 Induced by Salt and Phospholipid

Green tea extract increases cyclophosphamide-induced teratogenesis by modulating the expression of cytochrome P-450 mRNA

Structural requirements for inhibitors of cytochromes P450 2B: Assessment of the enzyme interaction with diamondoids

Effect of shenfu injection on CYP450s of rat liver

Effects of Matrine and Oxymatrine on Catalytic Activity of Cytochrome P450s in Rats

Promoting effects of monomethylarsonic acid, dimethylarsinic acid and trimethylarsine oxide on induction of rat liver preneoplastic glutathione S‐transferase placental form positive foci: A possible reactive oxygen species mechanism

Effects of benzyl isothiocyanate on rat and human cytochromes P450: identification of metabolites formed by P450 2B1

influence of diet composition on phase I and II biotransformation enzyme induction

Effect of selected antidepressant drugs on cytochrome P450 2B (CYP2B) in rat liver. An in vitro and in vivo study

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