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Challenging the Drug-Likeness Dogma for New Drug Discovery in Tuberculosis

Frontiers in microbiology, 2018-07, Vol.9, p.1367-1367

2018

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Insights on Mycobacterium leprae Efflux Pumps and Their Implications in Drug Resistance and Virulence

Frontiers in microbiology, 2018-12, Vol.9, p.3072-3072

2018

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Ethidium bromide transport across Mycobacterium smegmatis cell-wall: correlation with antibiotic resistance

BMC microbiology, 2011-02, Vol.11 (1), p.35-35

2011

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Role of the Mmr Efflux Pump in Drug Resistance in Mycobacterium tuberculosis

Antimicrobial Agents and Chemotherapy, 2013-02, Vol.57 (2), p.751-757

2013

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Interplay between Mutations and Efflux in Drug Resistant Clinical Isolates of Mycobacterium tuberculosis

Frontiers in microbiology, 2017-04, Vol.8, p.711-711

2017

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Antibiotic stress, genetic response and altered permeability of E. coli

PloS one, 2007-04, Vol.2 (4), p.e365-e365

2007

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Exploring the contribution of efflux on the resistance to fluoroquinolones in clinical isolates of Staphylococcus aureus

BMC microbiology, 2011-10, Vol.11 (1), p.241-241, Article 241

2011

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PolyTB: A genomic variation map for Mycobacterium tuberculosis

Tuberculosis (Edinburgh, Scotland), 2014-05, Vol.94 (3), p.346-354

2014

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Experimental Evidence for Limited in vivo Virulence of Mycobacterium africanum

Frontiers in microbiology, 2019-09, Vol.10, p.2102-2102

2019

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Demonstration of intrinsic efflux activity of Escherichia coli K-12 AG100 by an automated ethidium bromide method

International journal of antimicrobial agents, 2008-05, Vol.31 (5), p.458-462

2008

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Mode of action of the 2-phenylquinoline efflux inhibitor PQQ4R against Escherichia coli

PeerJ (San Francisco, CA), 2017-04, Vol.5, p.e3168-e3168, Article e3168

2017

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Clinical Concentrations of Thioridazine Kill Intracellular Multidrug-Resistant Mycobacterium tuberculosis

Antimicrobial Agents and Chemotherapy, 2003-03, Vol.47 (3), p.917-922

2003

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Inducement and Reversal of Tetracycline Resistance in Escherichia coli K-12 and Expression of Proton Gradient-Dependent Multidrug Efflux Pump Genes

Antimicrobial Agents and Chemotherapy, 2005-08, Vol.49 (8), p.3578-3582

2005

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The role of efflux pumps in macrolide resistance in Mycobacterium avium complex

International journal of antimicrobial agents, 2009-12, Vol.34 (6), p.529-533

2009

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Enhancement of antibiotic activity against poly-drug resistant Mycobacterium tuberculosis by phenothiazines

International journal of antimicrobial agents, 2001-03, Vol.17 (3), p.225-228

2001

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Fluorometric determination of ethidium bromide efflux kinetics in Escherichia coli

Journal of biological engineering, 2009-10, Vol.3 (1), p.18-18, Article 18

2009

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Relatedness of Mycobacterium avium subspecies hominissuis clinical isolates of human and porcine origins assessed by MLVA

Veterinary microbiology, 2014-09, Vol.173 (1-2), p.92-100

2014

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Why thioridazine in combination with antibiotics cures extensively drug-resistant Mycobacterium tuberculosis infections

International journal of antimicrobial agents, 2012-05, Vol.39 (5), p.376-380

2012

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Efflux pump inhibitors as a promising adjunct therapy against drug resistant tuberculosis: a new strategy to revisit mycobacterial targets and repurpose old drugs

Expert review of anti-infective therapy, 2020-08, Vol.18 (8), p.741-757

2020

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Spectinamides: a challenge, a proof, and a suggestion

Trends in microbiology (Regular ed.), 2014-04, Vol.22 (4), p.170-171

2014

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Isoniazid-Induced Transient High-Level Resistance in Mycobacterium tuberculosis

Antimicrobial Agents and Chemotherapy, 2002-09, Vol.46 (9), p.2804-2810

2002

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Antimicrobial susceptibility testing of Mycobacterium tuberculosis complex isolates – the EUCAST broth microdilution reference method for MIC determination

Clinical microbiology and infection, 2020-11, Vol.26 (11), p.1488-1492

2020

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Direct Application of the INNO-LiPA Rif.TB Line-Probe Assay for Rapid Identification of Mycobacterium tuberculosis Complex Strains and Detection of Rifampin Resistance in 360 Smear-Positive Respiratory Specimens from an Area of High Incidence of Multidrug-Resistant Tuberculosis

Journal of Clinical Microbiology, 2005-09, Vol.43 (9), p.4880-4884

2005

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Enhanced killing of intracellular multidrug-resistant Mycobacterium tuberculosis by compounds that affect the activity of efflux pumps

Journal of antimicrobial chemotherapy, 2007-06, Vol.59 (6), p.1237-1246

2007

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High-level resistance to isoniazid and ethionamide in multidrug-resistant Mycobacterium tuberculosis of the Lisboa family is associated with inhA double mutations

Journal of antimicrobial chemotherapy, 2013-08, Vol.68 (8), p.1728-1732

2013

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Challenging the Drug-Likeness Dogma for New Drug Discovery in Tuberculosis

Insights on Mycobacterium leprae Efflux Pumps and Their Implications in Drug Resistance and Virulence

Ethidium bromide transport across Mycobacterium smegmatis cell-wall: correlation with antibiotic resistance

Role of the Mmr Efflux Pump in Drug Resistance in Mycobacterium tuberculosis

Interplay between Mutations and Efflux in Drug Resistant Clinical Isolates of Mycobacterium tuberculosis

Antibiotic stress, genetic response and altered permeability of E. coli

Exploring the contribution of efflux on the resistance to fluoroquinolones in clinical isolates of Staphylococcus aureus

PolyTB: A genomic variation map for Mycobacterium tuberculosis

Experimental Evidence for Limited in vivo Virulence of Mycobacterium africanum

Demonstration of intrinsic efflux activity of Escherichia coli K-12 AG100 by an automated ethidium bromide method

Mode of action of the 2-phenylquinoline efflux inhibitor PQQ4R against Escherichia coli

Clinical Concentrations of Thioridazine Kill Intracellular Multidrug-Resistant Mycobacterium tuberculosis

Inducement and Reversal of Tetracycline Resistance in Escherichia coli K-12 and Expression of Proton Gradient-Dependent Multidrug Efflux Pump Genes

The role of efflux pumps in macrolide resistance in Mycobacterium avium complex

Enhancement of antibiotic activity against poly-drug resistant Mycobacterium tuberculosis by phenothiazines

Fluorometric determination of ethidium bromide efflux kinetics in Escherichia coli

Relatedness of Mycobacterium avium subspecies hominissuis clinical isolates of human and porcine origins assessed by MLVA

Why thioridazine in combination with antibiotics cures extensively drug-resistant Mycobacterium tuberculosis infections

Efflux pump inhibitors as a promising adjunct therapy against drug resistant tuberculosis: a new strategy to revisit mycobacterial targets and repurpose old drugs

Spectinamides: a challenge, a proof, and a suggestion

Isoniazid-Induced Transient High-Level Resistance in Mycobacterium tuberculosis

Antimicrobial susceptibility testing of Mycobacterium tuberculosis complex isolates – the EUCAST broth microdilution reference method for MIC determination

Direct Application of the INNO-LiPA Rif.TB Line-Probe Assay for Rapid Identification of Mycobacterium tuberculosis Complex Strains and Detection of Rifampin Resistance in 360 Smear-Positive Respiratory Specimens from an Area of High Incidence of Multidrug-Resistant Tuberculosis

Enhanced killing of intracellular multidrug-resistant Mycobacterium tuberculosis by compounds that affect the activity of efflux pumps

High-level resistance to isoniazid and ethionamide in multidrug-resistant Mycobacterium tuberculosis of the Lisboa family is associated with inhA double mutations

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