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A novel TK-NOG based humanized mouse model for the study of HBV and HCV infections

Biochemical and biophysical research communications, 2013-11, Vol.441 (1), p.230-235

2013

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Macrophages are requisite for angiogenesis of type H vessels during bone regeneration in mice

Bone (New York, N.Y.), 2022-01, Vol.154, p.116200-116200, Article 116200

2022

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Plasminogen activation independent of uPA and tPA maintains wound healing in gene-deficient mice

The EMBO journal, 2006-06, Vol.25 (12), p.2686-2697

2006

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Usefulness of humanized cDNA-uPA/SCID mice for the study of hepatitis B virus and hepatitis C virus virology

Journal of general virology, 2017-05, Vol.98 (5), p.1040-1047

2017

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Enterococcus faecalis promotes a migratory and invasive phenotype in colon cancer cells

Neoplasia (New York, N.Y.), 2022-05, Vol.27, p.100787-100787, Article 100787

2022

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The entry inhibitor Myrcludex-B efficiently blocks intrahepatic virus spreading in humanized mice previously infected with hepatitis B virus

Journal of hepatology, 2013-05, Vol.58 (5), p.861-867

2013

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Experimental in vitro and in vivo models for the study of human hepatitis B virus infection

Journal of hepatology, 2016-04, Vol.64 (1), p.S17-S31

2016

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Human liver chimeric mice as a new model of chronic hepatitis E virus infection and preclinical drug evaluation

Journal of hepatology, 2016-05, Vol.64 (5), p.1033-1040

2016

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Analytical strategy for the detection of ecdysterone and its metabolites in vivo in uPA(+/+)‐SCID mice with humanized liver, human urine samples, and estimation of prevalence of its use in anti‐doping samples

Drug testing and analysis, 2021-07, Vol.13 (7), p.1341-1353

2021

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Hepatitis Delta co-infection in humanized mice leads to pronounced induction of innate immune responses in comparison to HBV mono-infection

Journal of hepatology, 2015-08, Vol.63 (2), p.346-353

2015

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Urokinase-type plasminogen activator promotes corneal epithelial migration and nerve regeneration

Experimental eye research, 2023-08, Vol.233, p.109559-109559, Article 109559

2023

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uPAR-expressing melanoma exosomes promote angiogenesis by VE-Cadherin, EGFR and uPAR overexpression and rise of ERK1,2 signaling in endothelial cells

Cellular and molecular life sciences : CMLS, 2021-03, Vol.78 (6), p.3057-3072

2021

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Discovery of selective urokinase plasminogen activator (uPA) inhibitors as a potential treatment for multiple sclerosis

Bioorganic & medicinal chemistry letters, 2018-11, Vol.28 (20), p.3372-3375

2018

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uPA/uPAR and SERPINE1 in head and neck cancer: role in tumor resistance, metastasis, prognosis and therapy

Oncotarget, 2016-08, Vol.7 (35), p.57351-57366

2016

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Role of poFUT1 and O-fucosylation in placental angiogenesis

Biology of reproduction, 2023-04, Vol.108 (4), p.553-563

2023

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Urokinase Plasminogen Activator Deficiency Aggravates Cationic Bovine Serum Albumin–Induced Membranous Nephropathy Through T Helper Cell Type 2-Prone Immune Response in Mice

Laboratory investigation, 2023-07, Vol.103 (7), p.100146-100146, Article 100146

2023

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Downregulation of CFTR promotes epithelial-to-mesenchymal transition and is associated with poor prognosis of breast cancer

Biochimica et biophysica acta, 2013-12, Vol.1833 (12), p.2961-2969

2013

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Generation of improved mouse models for the study of hepatitis C virus

European journal of pharmacology, 2015-07, Vol.759, p.313-325

2015

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Urokinase plasminogen activator induces epithelial-mesenchymal and metastasis of pancreatic cancer through plasmin/MMP14/TGF-β axis, which is inhibited by 4-acetyl-antroquinonol B treatment

Phytomedicine (Stuttgart), 2022-06, Vol.100, p.154062-154062, Article 154062

2022

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Targeting uPA-uPAR interaction to improve intestinal epithelial barrier integrity in inflammatory bowel disease

EBioMedicine, 2022-01, Vol.75, p.103758-103758, Article 103758

2022

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Nafamostat Mesylate in Combination with the Mouse Amino-Terminal Fragment of Urokinase–Human Serum Albumin Improves the Treatment Outcome of Triple-Negative Breast Cancer Therapy

Molecular pharmaceutics, 2023-02, Vol.20 (2), p.905-917

2023

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The uPA System Differentially Alters Fibroblast Fate and Profibrotic Ability in Skin Fibrosis

Frontiers in immunology, 2022-03, Vol.13, p.845956-845956

2022

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Rapid mobilization of hematopoietic progenitors by AMD3100 and catecholamines is mediated by CXCR4-dependent SDF-1 release from bone marrow stromal cells

Leukemia, 2011-08, Vol.25 (8), p.1286-1296

2011

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uPA/uPAR system activation drives a glycolytic phenotype in melanoma cells

International journal of cancer, 2017-09, Vol.141 (6), p.1190-1200

2017

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Systematic evaluation of structure–property relationships and pharmacokinetics in 6-(hetero)aryl-substituted matched pair analogs of amiloride and 5-(N,N-hexamethylene)amiloride

Bioorganic & medicinal chemistry, 2021-05, Vol.37, p.116116, Article 116116

2021

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A novel TK-NOG based humanized mouse model for the study of HBV and HCV infections

Macrophages are requisite for angiogenesis of type H vessels during bone regeneration in mice

Plasminogen activation independent of uPA and tPA maintains wound healing in gene-deficient mice

Usefulness of humanized cDNA-uPA/SCID mice for the study of hepatitis B virus and hepatitis C virus virology

Enterococcus faecalis promotes a migratory and invasive phenotype in colon cancer cells

The entry inhibitor Myrcludex-B efficiently blocks intrahepatic virus spreading in humanized mice previously infected with hepatitis B virus

Experimental in vitro and in vivo models for the study of human hepatitis B virus infection

Human liver chimeric mice as a new model of chronic hepatitis E virus infection and preclinical drug evaluation

Analytical strategy for the detection of ecdysterone and its metabolites in vivo in uPA(+/+)‐SCID mice with humanized liver, human urine samples, and estimation of prevalence of its use in anti‐doping samples

Hepatitis Delta co-infection in humanized mice leads to pronounced induction of innate immune responses in comparison to HBV mono-infection

Urokinase-type plasminogen activator promotes corneal epithelial migration and nerve regeneration

uPAR-expressing melanoma exosomes promote angiogenesis by VE-Cadherin, EGFR and uPAR overexpression and rise of ERK1,2 signaling in endothelial cells

Discovery of selective urokinase plasminogen activator (uPA) inhibitors as a potential treatment for multiple sclerosis

uPA/uPAR and SERPINE1 in head and neck cancer: role in tumor resistance, metastasis, prognosis and therapy

Role of poFUT1 and O-fucosylation in placental angiogenesis

Urokinase Plasminogen Activator Deficiency Aggravates Cationic Bovine Serum Albumin–Induced Membranous Nephropathy Through T Helper Cell Type 2-Prone Immune Response in Mice

Downregulation of CFTR promotes epithelial-to-mesenchymal transition and is associated with poor prognosis of breast cancer

Generation of improved mouse models for the study of hepatitis C virus

Urokinase plasminogen activator induces epithelial-mesenchymal and metastasis of pancreatic cancer through plasmin/MMP14/TGF-β axis, which is inhibited by 4-acetyl-antroquinonol B treatment

Targeting uPA-uPAR interaction to improve intestinal epithelial barrier integrity in inflammatory bowel disease

Nafamostat Mesylate in Combination with the Mouse Amino-Terminal Fragment of Urokinase–Human Serum Albumin Improves the Treatment Outcome of Triple-Negative Breast Cancer Therapy

The uPA System Differentially Alters Fibroblast Fate and Profibrotic Ability in Skin Fibrosis

Rapid mobilization of hematopoietic progenitors by AMD3100 and catecholamines is mediated by CXCR4-dependent SDF-1 release from bone marrow stromal cells

uPA/uPAR system activation drives a glycolytic phenotype in melanoma cells

Systematic evaluation of structure–property relationships and pharmacokinetics in 6-(hetero)aryl-substituted matched pair analogs of amiloride and 5-(N,N-hexamethylene)amiloride

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