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Enhancing osteogenic potential of hDPSCs by resveratrol through reducing oxidative stress via the Sirt1/Nrf2 pathway

Pharmaceutical biology, 2022-12, Vol.60 (1), p.501-508

2022

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Spinal cord reconstitution with homologous neural grafts enables robust corticospinal regeneration

Nature medicine, 2016-05, Vol.22 (5), p.479-487

2016

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Divergence of Melanocortin Pathways in the Control of Food Intake and Energy Expenditure

Cell, 2005-11, Vol.123 (3), p.493-505

2005

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MeCP2 repression of G9a in regulation of pain and morphine reward

The Journal of neuroscience, 2014-07, Vol.34 (27), p.9076-9087

2014

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Quantitative high throughput screening using a primary human three-dimensional organotypic culture predicts in vivo efficacy

Nature communications, 2015-02, Vol.6 (1), p.6220-6220, Article 6220

2015

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Reversal of Chemoresistance in Ovarian Cancer by Co-Delivery of a P-Glycoprotein Inhibitor and Paclitaxel in a Liposomal Platform

Molecular cancer therapeutics, 2016-10, Vol.15 (10), p.2282-2293

2016

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LSD1n is an H4K20 demethylase regulating memory formation via transcriptional elongation control

Nature neuroscience, 2015-09, Vol.18 (9), p.1256-1264

2015

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Mitochondrial Reactive Oxygen Species in Lipotoxic Hearts Induce Post-Translational Modifications of AKAP121, DRP1, and OPA1 That Promote Mitochondrial Fission

Circulation research, 2018-01, Vol.122 (1), p.58-73

2018

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Dynamic Intestinal Stem Cell Plasticity and Lineage Remodeling by a Nutritional Environment Relevant to Human Risk for Tumorigenesis

Molecular cancer research, 2023-08, Vol.21 (8), p.808-824

2023

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The potential of hydrogel‐free tumoroids in head and neck squamous cell carcinoma

Cancer medicine (Malden, MA), 2024-08, Vol.13 (16), p.e70129-n/a

2024

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Arctiin abrogates osteoclastogenesis and bone resorption via suppressing RANKL-induced ROS and NFATc1 activation

Pharmacological research, 2020-09, Vol.159, p.104944, Article 104944

2020

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The nutritional environment determines which and how intestinal stem cells contribute to homeostasis and tumorigenesis

Carcinogenesis (New York), 2019-08, Vol.40 (8), p.937-946

2019

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A highly efficacious live attenuated mumps virus-based SARS-CoV-2 vaccine candidate expressing a six-proline stabilized prefusion spike

Proceedings of the National Academy of Sciences - PNAS, 2022-08, Vol.119 (33), p.e2201616119-e2201616119

2022

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Intestinal stem cell aging at single‐cell resolution: Transcriptional perturbations alter cell developmental trajectory reversed by gerotherapeutics

Aging cell, 2023-05, Vol.22 (5), p.e13802-n/a

2023

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Structure of Protein Related to Dan and Cerberus: Insights into the Mechanism of Bone Morphogenetic Protein Antagonism

Structure (London), 2013-08, Vol.21 (8), p.1417-1429

2013

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Genome-wide association analyses define pathogenic signaling pathways and prioritize drug targets for IgA nephropathy

Nature genetics, 2023-07, Vol.55 (7), p.1091-1105

2023

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siRNA-induced liver ApoB knockdown lowers serum LDL-cholesterol in a mouse model with human-like serum lipids[S]

Journal of lipid research, 2011-06, Vol.52 (6), p.1084-1097

2011

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Insight into prostate cancer osteolytic metastasis by RelB coordination of IL‐8 and S100A4

Clinical and translational medicine, 2024-10, Vol.14 (10), p.e70058-n/a

2024

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Overexpression of microRNA-21 is associated with elevated pro-inflammatory cytokines in dominant-negative TGF-β receptor type II mouse

Journal of autoimmunity, 2013-03, Vol.41, p.111-119

2013

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Immunostimulatory Tim-1-specific antibody deprograms Tregs and prevents transplant tolerance in mice

The Journal of clinical investigation, 2008-02, Vol.118 (2), p.735-741

2008

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Epitope‐specific anti‐nuclear antibodies are expressed in a mouse model of primary biliary cirrhosis and are cytokine‐dependent

Clinical and experimental immunology, 2012-06, Vol.168 (3), p.261-267

2012

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Genetic deletion of ADP-activated P2Y 12 receptor ameliorates lithium-induced nephrogenic diabetes insipidus in mice

Acta Physiologica, 2019-02, Vol.225 (2), p.e13191

2019

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Venous puncture wound hemostasis results in a vaulted thrombus structured by locally nucleated platelet aggregates

Communications biology, 2021-09, Vol.4 (1), p.1090-1090, Article 1090

2021

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Inhibition of Sphingosine 1-Phosphate Lyase for the Treatment of Rheumatoid Arthritis: Discovery of (E)-1-(4-((1R,2S,3R)-1,2,3,4-Tetrahydroxybutyl)-1H-imidazol-2-yl)ethanone Oxime (LX2931) and (1R,2S,3R)-1-(2-(Isoxazol-3-yl)-1H-imidazol-4-yl)butane-1,2,3,4-tetraol (LX2932)

Journal of medicinal chemistry, 2010-12, Vol.53 (24), p.8650-8662

2010

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Enhancing osteogenic potential of hDPSCs by resveratrol through reducing oxidative stress via the Sirt1/Nrf2 pathway

Spinal cord reconstitution with homologous neural grafts enables robust corticospinal regeneration

Divergence of Melanocortin Pathways in the Control of Food Intake and Energy Expenditure

MeCP2 repression of G9a in regulation of pain and morphine reward

Quantitative high throughput screening using a primary human three-dimensional organotypic culture predicts in vivo efficacy

Reversal of Chemoresistance in Ovarian Cancer by Co-Delivery of a P-Glycoprotein Inhibitor and Paclitaxel in a Liposomal Platform

LSD1n is an H4K20 demethylase regulating memory formation via transcriptional elongation control

Mitochondrial Reactive Oxygen Species in Lipotoxic Hearts Induce Post-Translational Modifications of AKAP121, DRP1, and OPA1 That Promote Mitochondrial Fission

Dynamic Intestinal Stem Cell Plasticity and Lineage Remodeling by a Nutritional Environment Relevant to Human Risk for Tumorigenesis

The potential of hydrogel‐free tumoroids in head and neck squamous cell carcinoma

Arctiin abrogates osteoclastogenesis and bone resorption via suppressing RANKL-induced ROS and NFATc1 activation

The nutritional environment determines which and how intestinal stem cells contribute to homeostasis and tumorigenesis

A highly efficacious live attenuated mumps virus-based SARS-CoV-2 vaccine candidate expressing a six-proline stabilized prefusion spike

Intestinal stem cell aging at single‐cell resolution: Transcriptional perturbations alter cell developmental trajectory reversed by gerotherapeutics

Structure of Protein Related to Dan and Cerberus: Insights into the Mechanism of Bone Morphogenetic Protein Antagonism

Genome-wide association analyses define pathogenic signaling pathways and prioritize drug targets for IgA nephropathy

siRNA-induced liver ApoB knockdown lowers serum LDL-cholesterol in a mouse model with human-like serum lipids[S]

Insight into prostate cancer osteolytic metastasis by RelB coordination of IL‐8 and S100A4

Overexpression of microRNA-21 is associated with elevated pro-inflammatory cytokines in dominant-negative TGF-β receptor type II mouse

Immunostimulatory Tim-1-specific antibody deprograms Tregs and prevents transplant tolerance in mice

Epitope‐specific anti‐nuclear antibodies are expressed in a mouse model of primary biliary cirrhosis and are cytokine‐dependent

Genetic deletion of ADP-activated P2Y 12 receptor ameliorates lithium-induced nephrogenic diabetes insipidus in mice

Venous puncture wound hemostasis results in a vaulted thrombus structured by locally nucleated platelet aggregates

The RUNX1/IL-34/CSF-1R axis is an autocrinally regulated modulator of resistance to BRAF-V600E inhibition in melanoma

Inhibition of Sphingosine 1-Phosphate Lyase for the Treatment of Rheumatoid Arthritis: Discovery of (E)-1-(4-((1R,2S,3R)-1,2,3,4-Tetrahydroxybutyl)-1H-imidazol-2-yl)ethanone Oxime (LX2931) and (1R,2S,3R)-1-(2-(Isoxazol-3-yl)-1H-imidazol-4-yl)butane-1,2,3,4-tetraol (LX2932)

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