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Functional effects of GRM1 suppression in human melanoma cells

Molecular cancer research, 2012-11, Vol.10 (11), p.1440-1450

2012

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Metabotropic glutamate receptor 1 and glutamate signaling in human melanoma

Cancer research (Chicago, Ill.), 2007-03, Vol.67 (5), p.2298-2305

2007

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Glutamatergic Pathway Targeting in Melanoma: Single-Agent and Combinatorial Therapies

Clinical cancer research, 2011-11, Vol.17 (22), p.7080-7092

2011

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Riluzole is a radio-sensitizing agent in an in vivo model of brain metastasis derived from GRM1 expressing human melanoma cells

Pigment cell and melanoma research, 2015-01, Vol.28 (1), p.105-109

2015

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Oncogenic activities of metabotropic glutamate receptor 1 (Grm1) in melanocyte transformation

Pigment cell and melanoma research, 2008-06, Vol.21 (3), p.368-378

2008

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Riluzole prodrugs for melanoma and ALS: Design, synthesis, and in vitro metabolic profiling

Bioorganic & medicinal chemistry, 2012-09, Vol.20 (18), p.5642-5648

2012

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AKT2 is a downstream target of metabotropic glutamate receptor 1 (Grm1)

Pigment cell and melanoma research, 2010-02, Vol.23 (1), p.103-111

2010

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Metabotropic glutamate receptor 1 (Grm1) is an oncogene in epithelial cells

Oncogene, 2013-09, Vol.32 (37), p.4366-4376

2013

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Riluzole Enhances Ionizing Radiation-Induced Cytotoxicity in Human Melanoma Cells that Ectopically Express Metabotropic Glutamate Receptor 1 In Vitro and In Vivo

Clinical cancer research, 2011-04, Vol.17 (7), p.1807-1814

2011

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Curcumin downregulates the constitutive activity of NF-kappaB and induces apoptosis in novel mouse melanoma cells

Melanoma research, 2007-10, Vol.17 (5), p.274

2007

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Laboratory mice born to wild mice have natural microbiota and model human immune responses

Science (American Association for the Advancement of Science), 2019-08, Vol.365 (6452)

2019

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mTOR Inhibition Alleviates Mitochondrial Disease in a Mouse Model of Leigh Syndrome

Science (American Association for the Advancement of Science), 2013-12, Vol.342 (6165), p.1524-1528

2013

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Methylation of p53 by Set7/9 Mediates p53 Acetylation and Activity In Vivo

Molecular cell, 2008-02, Vol.29 (3), p.392-400

2008

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Characterization of tritiated JNJ‐GluN2B‐5 (3‐[3H] 1‐(azetidin‐1‐yl)‐2‐(6‐(4‐fluoro‐3‐methyl‐phenyl)pyrrolo[3,2‐b]pyridin‐1‐yl)ethanone), a high affinity GluN2B radioligand with selectivity over sigma receptors

Journal of neurochemistry, 2024-09, Vol.168 (9), p.2654-2670

2024

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Progenitor cell proliferation in the retina is dependent on Notch-independent Sonic hedgehog/Hes1 activity

The Journal of cell biology, 2009-01, Vol.184 (1), p.101-112

2009

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IFNα Augments Clinical Efficacy of Regulatory T-cell Depletion with Denileukin Diftitox in Ovarian Cancer

Clinical cancer research, 2021-07, Vol.27 (13), p.3661-3673

2021

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An Artificial-Intelligence-Discovered Functional Ingredient, NRT_N0G5IJ, Derived from Pisum sativum , Decreases HbA1c in a Prediabetic Population

Nutrients, 2021-05, Vol.13 (5), p.1635

2021

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Conatumumab, a fully human agonist antibody to death receptor 5, induces apoptosis via caspase activation in multiple tumor types

Cancer biology & therapy, 2010-04, Vol.9 (8), p.618-631

2010

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A CD40 Agonist and PD-1 Antagonist Antibody Reprogram the Microenvironment of Nonimmunogenic Tumors to Allow T-cell-Mediated Anticancer Activity

Cancer immunology research, 2019-03, Vol.7 (3), p.428-442

2019

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Peripheral nerve injury and sensitization underlie pain associated with oral cancer perineural invasion

Pain (Amsterdam), 2020-11, Vol.161 (11), p.2592-2602

2020

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Adenosine-to-inosine RNA editing by ADAR1 is essential for normal murine erythropoiesis

Experimental hematology, 2016-10, Vol.44 (10), p.947-963

2016

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Identification of (R)‑(2-Chloro-3-(trifluoromethyl)phenyl)(1-(5-fluoropyridin-2-yl)-4-methyl-6,7-dihydro‑1H‑imidazo[4,5‑c]pyridin-5(4H)‑yl)methanone (JNJ 54166060), a Small Molecule Antagonist of the P2X7 receptor

Journal of medicinal chemistry, 2016-09, Vol.59 (18), p.8535-8548

2016

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Diagnostic and Therapeutic Potential of Amyloid-Reactive IgG Antibodies Contained in Human Sera

Journal of Immunology, 2006-06, Vol.176 (11), p.7071-7078

2006

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The SKI proto-oncogene enhances the in vivo repopulation of hematopoietic stem cells and causes myeloproliferative disease

Haematologica (Roma), 2014-04, Vol.99 (4), p.647-655

2014

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PET/MR Imaging of a Lung Metastasis Model of Clear Cell Renal Cell Carcinoma with (2S,4R)-4-[18F]Fluoroglutamine

Molecular imaging and biology, 2022-12, Vol.24 (6), p.959-972

2022

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Functional effects of GRM1 suppression in human melanoma cells

Metabotropic glutamate receptor 1 and glutamate signaling in human melanoma

Glutamatergic Pathway Targeting in Melanoma: Single-Agent and Combinatorial Therapies

Riluzole is a radio-sensitizing agent in an in vivo model of brain metastasis derived from GRM1 expressing human melanoma cells

Oncogenic activities of metabotropic glutamate receptor 1 (Grm1) in melanocyte transformation

Riluzole prodrugs for melanoma and ALS: Design, synthesis, and in vitro metabolic profiling

AKT2 is a downstream target of metabotropic glutamate receptor 1 (Grm1)

Metabotropic glutamate receptor 1 (Grm1) is an oncogene in epithelial cells

Riluzole Enhances Ionizing Radiation-Induced Cytotoxicity in Human Melanoma Cells that Ectopically Express Metabotropic Glutamate Receptor 1 In Vitro and In Vivo

Curcumin downregulates the constitutive activity of NF-kappaB and induces apoptosis in novel mouse melanoma cells

Laboratory mice born to wild mice have natural microbiota and model human immune responses

mTOR Inhibition Alleviates Mitochondrial Disease in a Mouse Model of Leigh Syndrome

Methylation of p53 by Set7/9 Mediates p53 Acetylation and Activity In Vivo

Characterization of tritiated JNJ‐GluN2B‐5 (3‐[3H] 1‐(azetidin‐1‐yl)‐2‐(6‐(4‐fluoro‐3‐methyl‐phenyl)pyrrolo[3,2‐b]pyridin‐1‐yl)ethanone), a high affinity GluN2B radioligand with selectivity over sigma receptors

Progenitor cell proliferation in the retina is dependent on Notch-independent Sonic hedgehog/Hes1 activity

IFNα Augments Clinical Efficacy of Regulatory T-cell Depletion with Denileukin Diftitox in Ovarian Cancer

An Artificial-Intelligence-Discovered Functional Ingredient, NRT_N0G5IJ, Derived from Pisum sativum , Decreases HbA1c in a Prediabetic Population

Conatumumab, a fully human agonist antibody to death receptor 5, induces apoptosis via caspase activation in multiple tumor types

A CD40 Agonist and PD-1 Antagonist Antibody Reprogram the Microenvironment of Nonimmunogenic Tumors to Allow T-cell-Mediated Anticancer Activity

Peripheral nerve injury and sensitization underlie pain associated with oral cancer perineural invasion

Adenosine-to-inosine RNA editing by ADAR1 is essential for normal murine erythropoiesis

Identification of (R)‑(2-Chloro-3-(trifluoromethyl)phenyl)(1-(5-fluoropyridin-2-yl)-4-methyl-6,7-dihydro‑1H‑imidazo[4,5‑c]pyridin-5(4H)‑yl)methanone (JNJ 54166060), a Small Molecule Antagonist of the P2X7 receptor

Diagnostic and Therapeutic Potential of Amyloid-Reactive IgG Antibodies Contained in Human Sera

The SKI proto-oncogene enhances the in vivo repopulation of hematopoietic stem cells and causes myeloproliferative disease

PET/MR Imaging of a Lung Metastasis Model of Clear Cell Renal Cell Carcinoma with (2S,4R)-4-[18F]Fluoroglutamine

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