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RUNX3 methylation drives hypoxia-induced cell proliferation and antiapoptosis in early tumorigenesis

Cell death and differentiation, 2021-04, Vol.28 (4), p.1251-1269

2021

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Runx3 Inactivation Is a Crucial Early Event in the Development of Lung Adenocarcinoma

Cancer cell, 2013-11, Vol.24 (5), p.603-616

2013

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Runx3 regulates iron metabolism via modulation of BMP signalling

Cell proliferation, 2021-12, Vol.54 (12), p.e13138-n/a

2021

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Bone Morphogenetic Protein-2 Stimulates Runx2 Acetylation

The Journal of biological chemistry, 2006-06, Vol.281 (24), p.16502-16511

2006

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Prolyl Isomerase Pin1-mediated Conformational Change and Subnuclear Focal Accumulation of Runx2 Are Crucial for Fibroblast Growth Factor 2 (FGF2)-induced Osteoblast Differentiation

The Journal of biological chemistry, 2014-03, Vol.289 (13), p.8828-8838

2014

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Histone deacetylase inhibitor MS‐275 stimulates bone formation in part by enhancing Dhx36‐mediated TNAP transcription

Journal of bone and mineral research, 2011-09, Vol.26 (9), p.2161-2173

2011

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Pin1-mediated Runx2 modification is critical for skeletal development

Journal of cellular physiology, 2013-12, Vol.228 (12), p.2377-2385

2013

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The RUNX3 Tumor Suppressor Upregulates Bim in Gastric Epithelial Cells Undergoing Transforming Growth Factorβ -Induced Apoptosis

Molecular and Cellular Biology, 2006-06, Vol.26 (12), p.4474-4488

2006

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Both the Smad and p38 MAPK pathways play a crucial role in Runx2 expression following induction by transforming growth factor-beta and bone morphogenetic protein

Oncogene, 2002-10, Vol.21 (47), p.7156-7163

2002

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Role of RUNX3 in Restriction Point Regulation

Cells (Basel, Switzerland), 2023-02, Vol.12 (5), p.708

2023

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Runx3 controls the axonal projection of proprioceptive dorsal root ganglion neurons

Nature neuroscience, 2002-10, Vol.5 (10), p.946-954

2002

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The Protein Kinase C Pathway Plays a Central Role in the Fibroblast Growth Factor-stimulated Expression and Transactivation Activity of Runx2

The Journal of biological chemistry, 2003-01, Vol.278 (1), p.319-326

2003

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Dlx5 Specifically Regulates Runx2 Type II Expression by Binding to Homeodomain-response Elements in the Runx2 Distal Promoter

The Journal of biological chemistry, 2005-10, Vol.280 (42), p.35579-35587

2005

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Identification of gene expression signature modulated by nicotinamide in a mouse bladder cancer model

PloS one, 2011-10, Vol.6 (10), p.e26131

2011

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Nicotinamide inhibits the early stage of carcinogen-induced hepatocarcinogenesis in mice and suppresses human hepatocellular carcinoma cell growth

Journal of cellular physiology, 2012-03, Vol.227 (3), p.899-908

2012

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Pim-1 kinase phosphorylates and stabilizes RUNX3 and alters its subcellular localization

Journal of cellular biochemistry, 2008-11, Vol.105 (4), p.1048-1058

2008

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Nicotinamide in Combination with EGFR-TKIs for the Treatment of Stage IV Lung Adenocarcinoma with EGFR Mutations: A Randomized Double-Blind (Phase IIb) Trial

Clinical cancer research, 2024-04, Vol.30 (8), p.1478-1487

2024

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Phosphorylation of the gastric tumor suppressor RUNX3 following H. pylori infection results in its localization to the cytoplasm

Journal of cellular physiology, 2012-03, Vol.227 (3), p.1071-1080

2012

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Runx3 is a crucial regulator of alveolar differentiation and lung tumorigenesis in mice

Differentiation (London), 2011-04, Vol.81 (4), p.261-268

2011

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Runx2 Protein Stabilizes Hypoxia-inducible Factor-1α through Competition with von Hippel-Lindau Protein (pVHL) and Stimulates Angiogenesis in Growth Plate Hypertrophic Chondrocytes

The Journal of biological chemistry, 2012-04, Vol.287 (18), p.14760-14771

2012

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Differential Requirements for Runx Proteins in CD4 Repression and Epigenetic Silencing during T Lymphocyte Development

Cell, 2002-11, Vol.111 (5), p.621-633

2002

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MicroRNA-34c Inversely Couples the Biological Functions of the Runt-related Transcription Factor RUNX2 and the Tumor Suppressor p53 in Osteosarcoma

The Journal of biological chemistry, 2013-07, Vol.288 (29), p.21307-21319

2013

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K-Ras -Activated Cells Can Develop into Lung Tumors When Runx3 -Mediated Tumor Suppressor Pathways Are Abrogated

Molecules and Cells, 2020, 43(10), , pp.889-897

2020

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Causal Relationship between the Loss of RUNX3 Expression and Gastric Cancer

Cell, 2002-04, Vol.109 (1), p.113-124

2002

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A Point Mutation R122C in RUNX3 Promotes the Expansion of Isthmus Stem Cells and Inhibits Their Differentiation in the Stomach

Cellular and molecular gastroenterology and hepatology, 2022-01, Vol.13 (5), p.1317-1345

2022

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RUNX3 methylation drives hypoxia-induced cell proliferation and antiapoptosis in early tumorigenesis

Runx3 Inactivation Is a Crucial Early Event in the Development of Lung Adenocarcinoma

Runx3 regulates iron metabolism via modulation of BMP signalling

Bone Morphogenetic Protein-2 Stimulates Runx2 Acetylation

Prolyl Isomerase Pin1-mediated Conformational Change and Subnuclear Focal Accumulation of Runx2 Are Crucial for Fibroblast Growth Factor 2 (FGF2)-induced Osteoblast Differentiation

Histone deacetylase inhibitor MS‐275 stimulates bone formation in part by enhancing Dhx36‐mediated TNAP transcription

Pin1-mediated Runx2 modification is critical for skeletal development

The RUNX3 Tumor Suppressor Upregulates Bim in Gastric Epithelial Cells Undergoing Transforming Growth Factorβ -Induced Apoptosis

Both the Smad and p38 MAPK pathways play a crucial role in Runx2 expression following induction by transforming growth factor-beta and bone morphogenetic protein

Role of RUNX3 in Restriction Point Regulation

Runx3 controls the axonal projection of proprioceptive dorsal root ganglion neurons

The Protein Kinase C Pathway Plays a Central Role in the Fibroblast Growth Factor-stimulated Expression and Transactivation Activity of Runx2

Dlx5 Specifically Regulates Runx2 Type II Expression by Binding to Homeodomain-response Elements in the Runx2 Distal Promoter

Identification of gene expression signature modulated by nicotinamide in a mouse bladder cancer model

Nicotinamide inhibits the early stage of carcinogen-induced hepatocarcinogenesis in mice and suppresses human hepatocellular carcinoma cell growth

Pim-1 kinase phosphorylates and stabilizes RUNX3 and alters its subcellular localization

Nicotinamide in Combination with EGFR-TKIs for the Treatment of Stage IV Lung Adenocarcinoma with EGFR Mutations: A Randomized Double-Blind (Phase IIb) Trial

Phosphorylation of the gastric tumor suppressor RUNX3 following H. pylori infection results in its localization to the cytoplasm

Runx3 is a crucial regulator of alveolar differentiation and lung tumorigenesis in mice

Runx2 Protein Stabilizes Hypoxia-inducible Factor-1α through Competition with von Hippel-Lindau Protein (pVHL) and Stimulates Angiogenesis in Growth Plate Hypertrophic Chondrocytes

Differential Requirements for Runx Proteins in CD4 Repression and Epigenetic Silencing during T Lymphocyte Development

MicroRNA-34c Inversely Couples the Biological Functions of the Runt-related Transcription Factor RUNX2 and the Tumor Suppressor p53 in Osteosarcoma

K-Ras -Activated Cells Can Develop into Lung Tumors When Runx3 -Mediated Tumor Suppressor Pathways Are Abrogated

Causal Relationship between the Loss of RUNX3 Expression and Gastric Cancer

A Point Mutation R122C in RUNX3 Promotes the Expansion of Isthmus Stem Cells and Inhibits Their Differentiation in the Stomach

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