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An Extensively Humanized Mouse Model to Predict Pathways of Drug Disposition and Drug/Drug Interactions, and to Facilitate Design of Clinical Trials

Drug metabolism and disposition, 2019-06, Vol.47 (6), p.601-615

2019

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Molecular aspects of chemical carcinogenesis: The roles of oncogenes and tumour suppressor genes

Toxicology, 1995-02, Vol.96 (3), p.173-194

Stanley, Lesley A.

1995

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Cloning and tissue-specific expression of the cDNA for the mouse Clara cell 10 kD protein: comparison of endogenous expression to rabbit uteroglobin promoter-driven transgene expression

American journal of respiratory cell and molecular biology, 1993-09, Vol.9 (3), p.231-238

1993

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Mutations associated with in vivo aflatoxin B1-induced carcinogenesis need not be present in the in vitro transformations by this toxin

Cancer letters, 1999-04, Vol.137 (2), p.173-181

1999

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Expression of SV40 T antigen under control of rabbit uteroglobin promoter in transgenic mice

American journal of physiology. Lung cellular and molecular physiology, 1991-08, Vol.261 (2), p.70-L76

1991

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Differential effects of recombinant interferon α on constitutive and inducible cytochrome P450 isozymes in mouse liver

Biochemical pharmacology, 1991-07, Vol.42 (2), p.311-320

1991

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Ras mutations in methylclofenapate-induced B6C3F1 and C57BL/10J mouse liver tumours

Carcinogenesis (New York), 1994-06, Vol.15 (6), p.1125-1131

1994

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A GWAS sequence variant for platelet volume marks an alternative DNM3 promoter in megakaryocytes near a MEIS1 binding site

Blood, 2012-12, Vol.120 (24), p.4859-4868

2012

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Cytoplasmic β-actin promoter produces germ cell and preimplantation embryonic transgene expression

Molecular reproduction and development, 1993-02, Vol.34 (2), p.117-126

1993

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Potentiation and suppression of mouse liver cytochrome P‐450 isozymes during the acute‐phase response induced by bacterial endotoxin

European journal of biochemistry, 1988-05, Vol.174 (1), p.31-36

1988

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Immunochemical detection of arylamine N-acetyltransferase during mouse embryonic development and in adult mouse brain

Teratology (Philadelphia), 1998-11, Vol.58 (5), p.174-182

1998

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Proto-oncogene activation in liver tumors of hepatocarcinogenesis-resistant strains of mice

Carcinogenesis (New York), 1992-12, Vol.13 (12), p.2427-2433

1992

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Localization of polymorphic N-acetyltransferase (NAT2) in tissues of inbred mice

Pharmacogenetics (London), 1997-04, Vol.7 (2), p.121-130

1997

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Coronavirus cell entry occurs through the endo-/lysosomal pathway in a proteolysis-dependent manner

PLoS pathogens, 2014-11, Vol.10 (11), p.e1004502-e1004502

2014

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Mutating the CX3C Motif in the G Protein Should Make a Live Respiratory Syncytial Virus Vaccine Safer and More Effective

Journal of virology, 2017-05, Vol.91 (10)

2017

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Metabolic Reprogramming Mediated by the mTORC2-IRF4 Signaling Axis Is Essential for Macrophage Alternative Activation

Immunity (Cambridge, Mass.), 2016-10, Vol.45 (4), p.817-830

2016

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A Cardiovascular Disease-Linked Gut Microbial Metabolite Acts via Adrenergic Receptors

Cell, 2020-03, Vol.180 (5), p.862-877.e22

2020

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Non-lethal Inhibition of Gut Microbial Trimethylamine Production for the Treatment of Atherosclerosis

Cell, 2015-12, Vol.163 (7), p.1585-1595

2015

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Molecular and anatomical characterization of parabrachial neurons and their axonal projections

eLife, 2022-11, Vol.11

2022

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Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk

Cell, 2016-03, Vol.165 (1), p.111-124

2016

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Human bone marrow hematopoietic stem cells are increased in frequency and myeloid-biased with age

Proceedings of the National Academy of Sciences - PNAS, 2011-12, Vol.108 (50), p.20012-20017

2011

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Memory CD8+ T Cells Use Cell-Intrinsic Lipolysis to Support the Metabolic Programming Necessary for Development

Immunity (Cambridge, Mass.), 2014-07, Vol.41 (1), p.75-88

2014

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Hematopoietic stem cell and progenitor cell mechanisms in myelodysplastic syndromes

Proceedings of the National Academy of Sciences - PNAS, 2013-02, Vol.110 (8), p.3011-3016

2013

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Minocycline Has Anti-inflammatory Effects and Reduces Cytotoxicity in an Ex Vivo Spinal Cord Slice Culture Model of West Nile Virus Infection

Journal of virology, 2017-11, Vol.91 (22)

2017

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Target-Selective Protein S-Nitrosylation by Sequence Motif Recognition

Cell, 2014-10, Vol.159 (3), p.623-634

2014

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An Extensively Humanized Mouse Model to Predict Pathways of Drug Disposition and Drug/Drug Interactions, and to Facilitate Design of Clinical Trials

Molecular aspects of chemical carcinogenesis: The roles of oncogenes and tumour suppressor genes

Cloning and tissue-specific expression of the cDNA for the mouse Clara cell 10 kD protein: comparison of endogenous expression to rabbit uteroglobin promoter-driven transgene expression

Mutations associated with in vivo aflatoxin B1-induced carcinogenesis need not be present in the in vitro transformations by this toxin

Expression of SV40 T antigen under control of rabbit uteroglobin promoter in transgenic mice

Differential effects of recombinant interferon α on constitutive and inducible cytochrome P450 isozymes in mouse liver

Ras mutations in methylclofenapate-induced B6C3F1 and C57BL/10J mouse liver tumours

A GWAS sequence variant for platelet volume marks an alternative DNM3 promoter in megakaryocytes near a MEIS1 binding site

Cytoplasmic β-actin promoter produces germ cell and preimplantation embryonic transgene expression

Potentiation and suppression of mouse liver cytochrome P‐450 isozymes during the acute‐phase response induced by bacterial endotoxin

Immunochemical detection of arylamine N-acetyltransferase during mouse embryonic development and in adult mouse brain

Proto-oncogene activation in liver tumors of hepatocarcinogenesis-resistant strains of mice

Localization of polymorphic N-acetyltransferase (NAT2) in tissues of inbred mice

Coronavirus cell entry occurs through the endo-/lysosomal pathway in a proteolysis-dependent manner

Mutating the CX3C Motif in the G Protein Should Make a Live Respiratory Syncytial Virus Vaccine Safer and More Effective

Metabolic Reprogramming Mediated by the mTORC2-IRF4 Signaling Axis Is Essential for Macrophage Alternative Activation

A Cardiovascular Disease-Linked Gut Microbial Metabolite Acts via Adrenergic Receptors

Non-lethal Inhibition of Gut Microbial Trimethylamine Production for the Treatment of Atherosclerosis

Molecular and anatomical characterization of parabrachial neurons and their axonal projections

Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk

Human bone marrow hematopoietic stem cells are increased in frequency and myeloid-biased with age

Memory CD8+ T Cells Use Cell-Intrinsic Lipolysis to Support the Metabolic Programming Necessary for Development

Hematopoietic stem cell and progenitor cell mechanisms in myelodysplastic syndromes

Minocycline Has Anti-inflammatory Effects and Reduces Cytotoxicity in an Ex Vivo Spinal Cord Slice Culture Model of West Nile Virus Infection

Target-Selective Protein S-Nitrosylation by Sequence Motif Recognition

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