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Farnesol and Geranylgeraniol Prevent Activation of Caspases by Aminobisphosphonates: Biochemical Evidence for Two Distinct Pharmacological Classes of Bisphosphonate Drugs

Molecular pharmacology, 1999-07, Vol.56 (1), p.131-140

1999

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Rapid Screening Method for Osteoclast Differentiation in Vitro That Measures Tartrate-resistant Acid Phosphatase 5b Activity Secreted into the Culture Medium

Clinical chemistry (Baltimore, Md.), 2000-11, Vol.46 (11), p.1751-1754

2000

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Zoledronic acid potentiates mTOR inhibition and abolishes the resistance of osteosarcoma cells to RAD001 (Everolimus): pivotal role of the prenylation process

Cancer research (Chicago, Ill.), 2010-12, Vol.70 (24), p.10329-10339

2010

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Liposome encapsulated zoledronate favours M1-like behaviour in murine macrophages cultured with soluble factors from breast cancer cells

BMC cancer, 2015-01, Vol.15 (1), p.4-4, Article 4

2015

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Opsonization, Biodistribution, Cellular Uptake and Apoptosis Study of PEGylated PBCA Nanoparticle as Potential Drug Delivery Carrier

Pharmaceutical research, 2012, Vol.29 (1), p.53-68

2012

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In Vivo Phosphoantigen Levels in Bisphosphonate-Treated Human Breast Tumors Trigger Vγ9Vδ2 T-cell Antitumor Cytotoxicity through ICAM-1 Engagement

Clinical cancer research, 2012-11, Vol.18 (22), p.6249-6259

2012

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Lysosomal-Mitochondrial Axis in Zoledronic Acid-induced Apoptosis in Human Follicular Lymphoma Cells

The Journal of biological chemistry, 2010-01, Vol.285 (3), p.1967-1979

2010

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Zoledronic acid-induced IPP/ApppI production in vivo

Life sciences (1973), 2007-09, Vol.81 (13), p.1066-1070

2007

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Targeted delivery via avidin fusion protein: Intracellular fate of biotinylated doxorubicin derivative and cellular uptake kinetics and biodistribution of biotinylated liposomes

European journal of pharmaceutical sciences, 2012-12, Vol.47 (5), p.848-856

2012

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Contrasting effects of alendronate and clodronate on RAW 264 macrophages: the role of a bisphosphonate metabolite

European journal of pharmaceutical sciences, 1999-05, Vol.8 (2), p.109-118

1999

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Activation of γδ T cells by bisphosphonates

Advances in experimental medicine and biology, 2010, Vol.658, p.11

2010

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Effect of liposomal and free bisphosphonates on the IL-1β, IL-6 and TNFα secretion from RAW 264 cells in vitro

Pharmaceutical research, 1995-06, Vol.12 (6), p.916-922

1995

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Zoledronic acid potentiates mTOR inhibition and abolishes the resistance of osteosarcoma cells to RAD001 (Everolimus): pivotal role of the prenylation process: Additive effect of ZOL and mTOR on osteosarcoma development

Cancer research (Chicago, Ill.), 2010-12, Vol.70 (24), p.10329-39

2010

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Bone metastasis targeting: A novel approach to reach bone using Zoledronate anchored PLGA nanoparticle as carrier system loaded with Docetaxel

Journal of controlled release, 2012-03, Vol.158 (3), p.470-478

2012

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Inhibition of mevalonate pathway is involved in alendronate-induced cell growth inhibition, but not in cytokine secretion from macrophages in vitro

European journal of pharmaceutical sciences, 2003-07, Vol.19 (4), p.223-230

2003

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The cellular uptake and metabolism of clodronate in RAW 264 macrophages

Pharmaceutical research, 2001-11, Vol.18 (11), p.1550-1555

2001

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Characteristics of clodronate-induced apoptosis in osteoclasts and macrophages

Molecular pharmacology, 1996-11, Vol.50 (5), p.1127-1138

1996

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Systemic Depletion of Macrophages by Liposomal Bisphosphonates Reduces Neointimal Formation Following Balloon-Injury in the Rat Carotid Artery

Journal of cardiovascular pharmacology, 2003-11, Vol.42 (5), p.671-679

2003

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High phosphoantigen levels in bisphosphonate-treated human breast tumors promote Vgamma9Vdelta2 T-cell chemotaxis and cytotoxicity in vivo

Cancer research (Chicago, Ill.), 2011-07, Vol.71 (13), p.4562-4572

2011

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Effects of tiludronate and ibandronate on the secretion of proinflammatory cytokines and nitric oxide from macrophages in vitro

Life sciences (1973), 1998, Vol.62 (8), p.PL95-PL102

1998

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Analysis of an adenine nucleotide-containing metabolite of clodronate using ion pair high-performance liquid chromatography–electrospray ionisation mass spectrometry

Journal of chromatography. B, Biomedical sciences and applications, 2000-02, Vol.738 (2), p.395-403

2000

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Identification of adenine nucleotide-containing metabolites of bisphosphonate drugs using ion-pair liquid chromatography–electrospray mass spectrometry

Journal of chromatography. B, Biomedical sciences and applications, 1997-12, Vol.704 (1), p.187-195

1997

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Growth Inhibition of Macrophage-Like and Other Cell Types by Liposome-Encapsulated, Calcium-Bound, and Free Bisphosphonates In Vitro

Journal of drug targeting, 1994, Vol.2 (4), p.299-308

1994

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In Vitro and In Vivo Effects of Tetrakisphosphonates on Bone Resorption, Tumor Osteolysis, Ectopic Calcification, and Macrophages

Journal of pharmaceutical sciences, 1997-03, Vol.86 (3), p.283-289

1997

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Different effects of three bisphosphonates on nitric oxide production by RAW 264 macrophage-like cells in vitro

The Journal of pharmacology and experimental therapeutics, 1996-05, Vol.277 (2), p.1097

1996

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Farnesol and Geranylgeraniol Prevent Activation of Caspases by Aminobisphosphonates: Biochemical Evidence for Two Distinct Pharmacological Classes of Bisphosphonate Drugs

Rapid Screening Method for Osteoclast Differentiation in Vitro That Measures Tartrate-resistant Acid Phosphatase 5b Activity Secreted into the Culture Medium

Zoledronic acid potentiates mTOR inhibition and abolishes the resistance of osteosarcoma cells to RAD001 (Everolimus): pivotal role of the prenylation process

Liposome encapsulated zoledronate favours M1-like behaviour in murine macrophages cultured with soluble factors from breast cancer cells

Opsonization, Biodistribution, Cellular Uptake and Apoptosis Study of PEGylated PBCA Nanoparticle as Potential Drug Delivery Carrier

In Vivo Phosphoantigen Levels in Bisphosphonate-Treated Human Breast Tumors Trigger Vγ9Vδ2 T-cell Antitumor Cytotoxicity through ICAM-1 Engagement

Lysosomal-Mitochondrial Axis in Zoledronic Acid-induced Apoptosis in Human Follicular Lymphoma Cells

Zoledronic acid-induced IPP/ApppI production in vivo

Targeted delivery via avidin fusion protein: Intracellular fate of biotinylated doxorubicin derivative and cellular uptake kinetics and biodistribution of biotinylated liposomes

Contrasting effects of alendronate and clodronate on RAW 264 macrophages: the role of a bisphosphonate metabolite

Activation of γδ T cells by bisphosphonates

Effect of liposomal and free bisphosphonates on the IL-1β, IL-6 and TNFα secretion from RAW 264 cells in vitro

Zoledronic acid potentiates mTOR inhibition and abolishes the resistance of osteosarcoma cells to RAD001 (Everolimus): pivotal role of the prenylation process: Additive effect of ZOL and mTOR on osteosarcoma development

Bone metastasis targeting: A novel approach to reach bone using Zoledronate anchored PLGA nanoparticle as carrier system loaded with Docetaxel

Inhibition of mevalonate pathway is involved in alendronate-induced cell growth inhibition, but not in cytokine secretion from macrophages in vitro

The cellular uptake and metabolism of clodronate in RAW 264 macrophages

Characteristics of clodronate-induced apoptosis in osteoclasts and macrophages

Systemic Depletion of Macrophages by Liposomal Bisphosphonates Reduces Neointimal Formation Following Balloon-Injury in the Rat Carotid Artery

High phosphoantigen levels in bisphosphonate-treated human breast tumors promote Vgamma9Vdelta2 T-cell chemotaxis and cytotoxicity in vivo

Effects of tiludronate and ibandronate on the secretion of proinflammatory cytokines and nitric oxide from macrophages in vitro

Analysis of an adenine nucleotide-containing metabolite of clodronate using ion pair high-performance liquid chromatography–electrospray ionisation mass spectrometry

Identification of adenine nucleotide-containing metabolites of bisphosphonate drugs using ion-pair liquid chromatography–electrospray mass spectrometry

Growth Inhibition of Macrophage-Like and Other Cell Types by Liposome-Encapsulated, Calcium-Bound, and Free Bisphosphonates In Vitro

In Vitro and In Vivo Effects of Tetrakisphosphonates on Bone Resorption, Tumor Osteolysis, Ectopic Calcification, and Macrophages

Different effects of three bisphosphonates on nitric oxide production by RAW 264 macrophage-like cells in vitro

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