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Targeting NAD+ Metabolism as Interventions for Mitochondrial Disease

Scientific reports, 2019-02, Vol.9 (1), p.3073-3073, Article 3073

2019

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Normalization of NAD+ Redox Balance as a Therapy for Heart Failure

Circulation (New York, N.Y.), 2016-09, Vol.134 (12), p.883-894

2016

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Mitochondrial protein interactome elucidated by chemical cross-linking mass spectrometry

Proceedings of the National Academy of Sciences - PNAS, 2017-02, Vol.114 (7), p.1732-1737

2017

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Enhanced cellular uptake of aminosilane-coated superparamagnetic iron oxide nanoparticles in mammalian cell lines

International journal of nanomedicine, 2012-01, Vol.7 (default), p.953-964

2012

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Chemical Crosslinking Mass Spectrometry Analysis of Protein Conformations and Supercomplexes in Heart Tissue

Cell systems, 2018-01, Vol.6 (1), p.136-141.e5

2018

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Redox regulation of MAPK phosphatase 1 controls monocyte migration and macrophage recruitment

Proceedings of the National Academy of Sciences - PNAS, 2012-10, Vol.109 (41), p.E2803-E2812

2012

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Mitochondrial Complex I Deficiency Increases Protein Acetylation and Accelerates Heart Failure

Cell metabolism, 2013-08, Vol.18 (2), p.239-250

2013

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Revealing Pathway Dynamics in Heart Diseases by Analyzing Multiple Differential Networks

PLoS computational biology, 2015-06, Vol.11 (6), p.e1004332-e1004332

2015

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NADPH oxidase 4 mediates monocyte priming and accelerated chemotaxis induced by metabolic stress

Arteriosclerosis, thrombosis, and vascular biology, 2012-02, Vol.32 (2), p.415-426

2012

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Synthesis and Evaluation of Structurally Diverse C‑2-Substituted Thienopyrimidine-Based Inhibitors of the Human Geranylgeranyl Pyrophosphate Synthase

Journal of medicinal chemistry, 2022-02, Vol.65 (3), p.2471-2496

2022

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Discovery and Evaluation of C6-Substituted Pyrazolopyrimidine-Based Bisphosphonate Inhibitors of the Human Geranylgeranyl Pyrophosphate Synthase and Evaluation of Their Antitumor Efficacy in Multiple Myeloma, Pancreatic Ductal Adenocarcinoma, and Colorectal Cancer

Journal of medicinal chemistry, 2023-12, Vol.66 (23), p.15776-15800

2023

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Identification of active components in Andrographis paniculata targeting on CD81 in esophageal cancer in vitro and in vivo

Phytomedicine (Stuttgart), 2022-07, Vol.102, p.154183-154183, Article 154183

2022

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Thiol oxidative stress induced by metabolic disorders amplifies macrophage chemotactic responses and accelerates atherogenesis and kidney injury in LDL receptor-deficient mice

Arteriosclerosis, thrombosis, and vascular biology, 2009-11, Vol.29 (11), p.1779-1786

2009

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Mitochondrial proteins that regulate apoptosis and necrosis are induced in mouse fatty liver

Hepatology (Baltimore, Md.), 1999-04, Vol.29 (4), p.1131-1138

1999

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Type III-B rotaxane dendrimers

Chemical communications (Cambridge, England), 2013-11, Vol.49 (92), p.10781-10783

2013

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Anti-inflammatory and Analgesic Effects of Elephantopus tomentosus Ethanolic Extract

Journal of Acupuncture & Meridian Studies, 2009, 2(4), 6, pp.280-287

2009

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Impaired Liver Regeneration in Inducible Nitric Oxide Synthase-Deficient Mice

Proceedings of the National Academy of Sciences - PNAS, 1998-11, Vol.95 (23), p.13829-13834

1998

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Simultaneous Analysis of Major Coenzymes of Cellular Redox Reactions and Energy Using ex Vivo (1)H NMR Spectroscopy

Analytical chemistry (Washington), 2016-05, Vol.88 (9), p.4817-4824

2016

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NAD + Redox Imbalance in the Heart Exacerbates Diabetic Cardiomyopathy

Circulation. Heart failure, 2021-08, Vol.14 (8), p.e008170-e008170

2021

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Sexually dimorphic effects of SARM1 deletion on cardiac NAD + metabolism and function

American journal of physiology. Heart and circulatory physiology, 2022-10, Vol.323 (4), p.H774-H781

2022

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Promoting PGC-1α-driven mitochondrial biogenesis is detrimental in pressure-overloaded mouse hearts

American journal of physiology. Heart and circulatory physiology, 2014-11, Vol.307 (9), p.H1307-H1316

2014

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Elimination of NADPH Oxidase Activity Promotes Reductive Stress and Sensitizes the Heart to Ischemic Injury

Journal of the American Heart Association, 2014-01, Vol.3 (1), p.e000555-n/a

2014

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EF1α-associated protein complexes affect dendritic spine plasticity by regulating microglial phagocytosis in Fmr1 knock-out mice

Molecular psychiatry, 2024-04, Vol.29 (4), p.1099-1113

2024

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Disrupting GluA2-GAPDH Interaction Affects Axon and Dendrite Development

Scientific reports, 2016-07, Vol.6 (1), p.30458-30458, Article 30458

2016

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Targeting NAD+ Metabolism as Interventions for Mitochondrial Disease

Normalization of NAD+ Redox Balance as a Therapy for Heart Failure

Mitochondrial protein interactome elucidated by chemical cross-linking mass spectrometry

Enhanced cellular uptake of aminosilane-coated superparamagnetic iron oxide nanoparticles in mammalian cell lines

Genetic architecture of heart mitochondrial proteome influencing cardiac hypertrophy

Chemical Crosslinking Mass Spectrometry Analysis of Protein Conformations and Supercomplexes in Heart Tissue

Redox regulation of MAPK phosphatase 1 controls monocyte migration and macrophage recruitment

Mitochondrial Complex I Deficiency Increases Protein Acetylation and Accelerates Heart Failure

Revealing Pathway Dynamics in Heart Diseases by Analyzing Multiple Differential Networks

NADPH oxidase 4 mediates monocyte priming and accelerated chemotaxis induced by metabolic stress

Synthesis and Evaluation of Structurally Diverse C‑2-Substituted Thienopyrimidine-Based Inhibitors of the Human Geranylgeranyl Pyrophosphate Synthase

Discovery and Evaluation of C6-Substituted Pyrazolopyrimidine-Based Bisphosphonate Inhibitors of the Human Geranylgeranyl Pyrophosphate Synthase and Evaluation of Their Antitumor Efficacy in Multiple Myeloma, Pancreatic Ductal Adenocarcinoma, and Colorectal Cancer

Identification of active components in Andrographis paniculata targeting on CD81 in esophageal cancer in vitro and in vivo

Thiol oxidative stress induced by metabolic disorders amplifies macrophage chemotactic responses and accelerates atherogenesis and kidney injury in LDL receptor-deficient mice

Mitochondrial proteins that regulate apoptosis and necrosis are induced in mouse fatty liver

Type III-B rotaxane dendrimers

Anti-inflammatory and Analgesic Effects of Elephantopus tomentosus Ethanolic Extract

Impaired Liver Regeneration in Inducible Nitric Oxide Synthase-Deficient Mice

Simultaneous Analysis of Major Coenzymes of Cellular Redox Reactions and Energy Using ex Vivo (1)H NMR Spectroscopy

NAD + Redox Imbalance in the Heart Exacerbates Diabetic Cardiomyopathy

Sexually dimorphic effects of SARM1 deletion on cardiac NAD + metabolism and function

Promoting PGC-1α-driven mitochondrial biogenesis is detrimental in pressure-overloaded mouse hearts

Elimination of NADPH Oxidase Activity Promotes Reductive Stress and Sensitizes the Heart to Ischemic Injury

EF1α-associated protein complexes affect dendritic spine plasticity by regulating microglial phagocytosis in Fmr1 knock-out mice

Disrupting GluA2-GAPDH Interaction Affects Axon and Dendrite Development

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