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Disruption of fast axonal transport is a pathogenic mechanism for intraneuronal amyloid beta

Proceedings of the National Academy of Sciences - PNAS, 2009-04, Vol.106 (14), p.5907-5912

2009

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Preparation of fluorescently-labeled amyloid-beta peptide assemblies: the effect of fluorophore conjugation on structure and function

Journal of molecular recognition, 2009-09, Vol.22 (5), p.403-413

2009

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Lipidation of apolipoprotein E influences its isoform-specific interaction with Alzheimer's amyloid beta peptides

Biochemical journal, 2000-06, Vol.348 Pt 2 (2), p.359-365

2000

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Unique Lipoproteins Secreted by Primary Astrocytes From Wild Type, apoE (−/−), and Human apoE Transgenic Mice

The Journal of biological chemistry, 1999-10, Vol.274 (42), p.30001-30007

1999

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Glial Fibrillary Acidic Protein-Apolipoprotein E (apoE) Transgenic Mice: Astrocyte-Specific Expression and Differing Biological Effects of Astrocyte-Secreted apoE3 and apoE4 Lipoproteins

The Journal of neuroscience, 1998-05, Vol.18 (9), p.3261-3272

1998

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Cellular Catabolism of Lipid Poor Apolipoprotein E via Cell Surface LDL Receptor-Related Protein

Journal of biochemistry (Tokyo), 2002-11, Vol.132 (5), p.743-749

2002

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The APOE4 allele shows opposite sex bias in microbleeds and Alzheimer's disease of humans and mice

Neurobiology of aging, 2016-01, Vol.37, p.47-57

2016

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ApoE isoform affects LTP in human targeted replacement mice

Neuroreport, 2004-12, Vol.15 (17), p.2655-2658

2004

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Apolipoprotein E modulates γ‐secretase cleavage of the amyloid precursor protein

Journal of neurochemistry, 2004-09, Vol.90 (5), p.1132-1143

2004

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Self-Assembly of HEK Cell-Secreted ApoE Particles Resembles ApoE Enrichment of Lipoproteins as a Ligand for the LDL Receptor-Related Protein

Biochemistry (Easton), 2006-01, Vol.45 (2), p.381-390

2006

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Blockade of nicotinic acetylcholine receptors suppresses hippocampal long-term potentiation in wild-type but not ApoE4 targeted replacement mice

Journal of neuroscience research, 2005-12, Vol.82 (6), p.771-777

2005

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Characterization of serum-stimulated lipoprotein lipase from bovine heart

International journal of biochemistry, 1991, Vol.23 (4), p.405-411

1991

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APOE genotype alters glial activation and loss of synaptic markers in mice

Glia, 2012-04, Vol.60 (4), p.559-569

2012

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Response to Gamma-radiation of Mouse Embryonic Lung Cultivated in Vitro

International journal of radiation biology, 1962-01, Vol.5 (6), p.579-589

1962

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Human APOE4 increases microglia reactivity at Aβ plaques in a mouse model of Aβ deposition

Journal of neuroinflammation, 2014-06, Vol.11 (1), p.111-111, Article 111

2014

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Prion protein inhibits fast axonal transport through a mechanism involving casein kinase 2

PloS one, 2017-12, Vol.12 (12), p.e0188340

2017

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PRELIMINARY DATA ON THE RELATIVE BIOLOGICAL EFFECTIVENESS (RBE) OF THE 1000 MEV GAMMA-RADIATION DELIVERED BY THE FRASCATI ELECTRON-SYNCHROTRON

International journal of radiation biology and related studies in physics, chemistry and medicine, 1964, Vol.8, p.233

1964

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Murine Gut Microbiome Association With APOE Alleles

Frontiers in immunology, 2020-02, Vol.11, p.200-200

2020

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Cognitive effects of cell-derived and synthetically derived Aβ oligomers

Neurobiology of aging, 2011-10, Vol.32 (10), p.1784-1794

2011

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EFAD transgenic mice as a human APOE relevant preclinical model of Alzheimer's disease

Journal of lipid research, 2017-09, Vol.58 (9), p.1733-1755

2017

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Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody

Molecular neurodegeneration, 2012-03, Vol.7 (1), p.8-8, Article 8

2012

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The detrimental effects of APOE4 on risk for Alzheimer's disease may result from altered dendritic spine density, synaptic proteins, and estrogen receptor alpha

Neurobiology of aging, 2022-04, Vol.112, p.74-86

2022

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APOE4 genotype or ovarian hormone loss influence open field exploration in an EFAD mouse model of Alzheimer's disease

Hormones and behavior, 2022-04, Vol.140, p.105124-105124, Article 105124

2022

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A small-molecule TLR4 antagonist reduced neuroinflammation in female E4FAD mice

Alzheimer's research & therapy, 2023-10, Vol.15 (1), p.181-181, Article 181

2023

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Estradiol improves behavior in FAD transgenic mice that express APOE3 but not APOE4 after ovariectomy

Frontiers in endocrinology (Lausanne), 2024-04, Vol.15, p.1374825

2024

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Disruption of fast axonal transport is a pathogenic mechanism for intraneuronal amyloid beta

Preparation of fluorescently-labeled amyloid-beta peptide assemblies: the effect of fluorophore conjugation on structure and function

Lipidation of apolipoprotein E influences its isoform-specific interaction with Alzheimer's amyloid beta peptides

Unique Lipoproteins Secreted by Primary Astrocytes From Wild Type, apoE (−/−), and Human apoE Transgenic Mice

Glial Fibrillary Acidic Protein-Apolipoprotein E (apoE) Transgenic Mice: Astrocyte-Specific Expression and Differing Biological Effects of Astrocyte-Secreted apoE3 and apoE4 Lipoproteins

Cellular Catabolism of Lipid Poor Apolipoprotein E via Cell Surface LDL Receptor-Related Protein

The APOE4 allele shows opposite sex bias in microbleeds and Alzheimer's disease of humans and mice

ApoE isoform affects LTP in human targeted replacement mice

Apolipoprotein E modulates γ‐secretase cleavage of the amyloid precursor protein

Self-Assembly of HEK Cell-Secreted ApoE Particles Resembles ApoE Enrichment of Lipoproteins as a Ligand for the LDL Receptor-Related Protein

Blockade of nicotinic acetylcholine receptors suppresses hippocampal long-term potentiation in wild-type but not ApoE4 targeted replacement mice

Characterization of serum-stimulated lipoprotein lipase from bovine heart

APOE genotype alters glial activation and loss of synaptic markers in mice

Response to Gamma-radiation of Mouse Embryonic Lung Cultivated in Vitro

Human APOE4 increases microglia reactivity at Aβ plaques in a mouse model of Aβ deposition

Prion protein inhibits fast axonal transport through a mechanism involving casein kinase 2

PRELIMINARY DATA ON THE RELATIVE BIOLOGICAL EFFECTIVENESS (RBE) OF THE 1000 MEV GAMMA-RADIATION DELIVERED BY THE FRASCATI ELECTRON-SYNCHROTRON

Murine Gut Microbiome Association With APOE Alleles

Cognitive effects of cell-derived and synthetically derived Aβ oligomers

EFAD transgenic mice as a human APOE relevant preclinical model of Alzheimer's disease

Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody

The detrimental effects of APOE4 on risk for Alzheimer's disease may result from altered dendritic spine density, synaptic proteins, and estrogen receptor alpha

APOE4 genotype or ovarian hormone loss influence open field exploration in an EFAD mouse model of Alzheimer's disease

A small-molecule TLR4 antagonist reduced neuroinflammation in female E4FAD mice

Estradiol improves behavior in FAD transgenic mice that express APOE3 but not APOE4 after ovariectomy

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