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Synthetic lethal interactions between EGFR and PARP inhibition in human triple negative breast cancer cells

PloS one, 2012-10, Vol.7 (10), p.e46614

2012

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The antitumor effects of entinostat in ovarian cancer require adaptive immunity

Cancer, 2018-12, Vol.124 (24), p.4657-4666

2018

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Endoglin (CD105) Contributes to Platinum Resistance and Is A Target for Tumor-Specific Therapy in Epithelial Ovarian Cancer

Clinical cancer research, 2013-01, Vol.19 (1), p.170-182

2013

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Targeting BRCA1 Localization to Augment Breast Tumor Sensitivity to Poly(ADP-Ribose) Polymerase Inhibition

Cancer research (Chicago, Ill.), 2012-11, Vol.72 (21), p.5547-5555

2012

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Kinomic exploration of temozolomide and radiation resistance in Glioblastoma multiforme xenolines

Radiotherapy and oncology, 2014-06, Vol.111 (3), p.468-474

2014

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A Novel Translational PET Imaging Approach to Quantifying Distal Tumor Immune Activation After Targeted Radiation Therapy and Checkpoint Blockade

International journal of radiation oncology, biology, physics, 2024-04, Vol.118 (5), p.1217-1227

2024

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CHK1/2 Inhibitor Prexasertib Suppresses NOTCH Signaling and Enhances Cytotoxicity of Cisplatin and Radiation in Head and Neck Squamous Cell Carcinoma

Molecular cancer therapeutics, 2020-06, Vol.19 (6), p.1279-1288

2020

Volltextzugriff (PDF)

PSPH promotes melanoma growth and metastasis by metabolic deregulation-mediated transcriptional activation of NR4A1

Oncogene, 2021-04, Vol.40 (13), p.2448-2462

2021

Volltextzugriff (PDF)

Combining Chk1/2 Inhibition with Cetuximab and Radiation Enhances In Vitro and In Vivo Cytotoxicity in Head and Neck Squamous Cell Carcinoma

Molecular cancer therapeutics, 2017-04, Vol.16 (4), p.591-600

2017

Volltextzugriff (PDF)

The BET inhibitor JQ1 attenuates double-strand break repair and sensitizes models of pancreatic ductal adenocarcinoma to PARP inhibitors

EBioMedicine, 2019-06, Vol.44, p.419-430

2019

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BET inhibition decreases HMGCS2 and sensitizes resistant pancreatic tumors to gemcitabine

Cancer letters, 2024-06, Vol.592, p.216919, Article 216919

2024

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DNA double strand break repair defect and sensitivity to poly ADP-ribose polymerase (PARP) inhibition in human papillomavirus 16-positive head and neck squamous cell carcinoma

Oncotarget, 2015-09, Vol.6 (29), p.26995-27007

2015

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Niclosamide and its analogs are potent inhibitors of Wnt/β-catenin, mTOR and STAT3 signaling in ovarian cancer

Oncotarget, 2016-12, Vol.7 (52), p.86803-86815

2016

Volltextzugriff (PDF)

Poly(N‑vinylpyrrolidone)-block-Poly(dimethylsiloxane)-block-Poly(N‑vinylpyrrolidone) Triblock Copolymer Polymersomes for Delivery of PARP1 siRNA to Breast Cancers

ACS applied bio materials, 2022-04, Vol.5 (4), p.1670-1682

2022

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MARCKS Regulates Growth and Radiation Sensitivity and Is a Novel Prognostic Factor for Glioma

Clinical cancer research, 2012-06, Vol.18 (11), p.3030-3041

2012

Volltextzugriff (PDF)

RNF2 ablation reprograms the tumor-immune microenvironment and stimulates durable NK and CD4 + T-cell-dependent antitumor immunity

Nature cancer, 2021-10, Vol.2 (10), p.1018

2021

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Lithium-mediated protection of hippocampal cells involves enhancement of DNA-PK-dependent repair in mice

The Journal of clinical investigation, 2009-05, Vol.119 (5), p.1124-1135

2009

Volltextzugriff (PDF)

Treatment of small cell lung cancer with TRA-8 in combination with cisplatin and radiation

Radiotherapy and oncology, 2011-10, Vol.101 (1), p.183-189

2011

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The BET bromodomain inhibitor JQ1 suppresses growth of pancreatic ductal adenocarcinoma in patient-derived xenograft models

Oncogene, 2016-02, Vol.35 (7), p.833-845

2016

Volltextzugriff (PDF)

Glycogen synthase kinase 3beta inhibition enhances repair of DNA double-strand breaks in irradiated hippocampal neurons

Neuro-oncology (Charlottesville, Va.), 2011-05, Vol.13 (5), p.459

2011

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VDAC oligomers form mitochondrial pores to release mtDNA fragments and promote lupus-like disease

Science (American Association for the Advancement of Science), 2019-12, Vol.366 (6472), p.1531-1536

2019

Volltextzugriff (PDF)

Discovery and Pharmacological Characterization of JNJ-42756493 (Erdafitinib), a Functionally Selective Small-Molecule FGFR Family Inhibitor

Molecular cancer therapeutics, 2017-06, Vol.16 (6), p.1010-1020

2017

Volltextzugriff (PDF)

Selective inhibition of IDO1 effectively regulates mediators of antitumor immunity

Blood, 2010-04, Vol.115 (17), p.3520-3530

2010

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Hydroxyamidine inhibitors of indoleamine-2,3-dioxygenase potently suppress systemic tryptophan catabolism and the growth of IDO-expressing tumors

Molecular cancer therapeutics, 2010-02, Vol.9 (2), p.489-498

2010

Volltextzugriff (PDF)

Interleukin (IL)-1 Receptor Signaling Is Required for Complete Taste Bud Regeneration and the Recovery of Neural Taste Responses following Axotomy

The Journal of neuroscience, 2023-05, Vol.43 (19), p.3439-3455

2023

Volltextzugriff (PDF)

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Synthetic lethal interactions between EGFR and PARP inhibition in human triple negative breast cancer cells

The antitumor effects of entinostat in ovarian cancer require adaptive immunity

Endoglin (CD105) Contributes to Platinum Resistance and Is A Target for Tumor-Specific Therapy in Epithelial Ovarian Cancer

Targeting BRCA1 Localization to Augment Breast Tumor Sensitivity to Poly(ADP-Ribose) Polymerase Inhibition

Kinomic exploration of temozolomide and radiation resistance in Glioblastoma multiforme xenolines

A Novel Translational PET Imaging Approach to Quantifying Distal Tumor Immune Activation After Targeted Radiation Therapy and Checkpoint Blockade

CHK1/2 Inhibitor Prexasertib Suppresses NOTCH Signaling and Enhances Cytotoxicity of Cisplatin and Radiation in Head and Neck Squamous Cell Carcinoma

PSPH promotes melanoma growth and metastasis by metabolic deregulation-mediated transcriptional activation of NR4A1

Combining Chk1/2 Inhibition with Cetuximab and Radiation Enhances In Vitro and In Vivo Cytotoxicity in Head and Neck Squamous Cell Carcinoma

The BET inhibitor JQ1 attenuates double-strand break repair and sensitizes models of pancreatic ductal adenocarcinoma to PARP inhibitors

BET inhibition decreases HMGCS2 and sensitizes resistant pancreatic tumors to gemcitabine

DNA double strand break repair defect and sensitivity to poly ADP-ribose polymerase (PARP) inhibition in human papillomavirus 16-positive head and neck squamous cell carcinoma

Niclosamide and its analogs are potent inhibitors of Wnt/β-catenin, mTOR and STAT3 signaling in ovarian cancer

Poly(N‑vinylpyrrolidone)-block-Poly(dimethylsiloxane)-block-Poly(N‑vinylpyrrolidone) Triblock Copolymer Polymersomes for Delivery of PARP1 siRNA to Breast Cancers

MARCKS Regulates Growth and Radiation Sensitivity and Is a Novel Prognostic Factor for Glioma

RNF2 ablation reprograms the tumor-immune microenvironment and stimulates durable NK and CD4 + T-cell-dependent antitumor immunity

Lithium-mediated protection of hippocampal cells involves enhancement of DNA-PK-dependent repair in mice

Treatment of small cell lung cancer with TRA-8 in combination with cisplatin and radiation

The BET bromodomain inhibitor JQ1 suppresses growth of pancreatic ductal adenocarcinoma in patient-derived xenograft models

Glycogen synthase kinase 3beta inhibition enhances repair of DNA double-strand breaks in irradiated hippocampal neurons

VDAC oligomers form mitochondrial pores to release mtDNA fragments and promote lupus-like disease

Discovery and Pharmacological Characterization of JNJ-42756493 (Erdafitinib), a Functionally Selective Small-Molecule FGFR Family Inhibitor

Selective inhibition of IDO1 effectively regulates mediators of antitumor immunity

Hydroxyamidine inhibitors of indoleamine-2,3-dioxygenase potently suppress systemic tryptophan catabolism and the growth of IDO-expressing tumors

Interleukin (IL)-1 Receptor Signaling Is Required for Complete Taste Bud Regeneration and the Recovery of Neural Taste Responses following Axotomy

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