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Moderately high intake of folic acid has a negative impact on mouse embryonic development

Birth defects research. A Clinical and molecular teratology, 2013-01, Vol.97 (1), p.47-52

2013

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High folic acid consumption leads to pseudo-MTHFR deficiency, altered lipid metabolism, and liver injury in mice

The American journal of clinical nutrition, 2015-03, Vol.101 (3), p.646-658

2015

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Steatosis in Mice Is Associated with Gender, Folate Intake, and Expression of Genes of One-Carbon Metabolism

The Journal of nutrition, 2010-10, Vol.140 (10), p.1736-1741

2010

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High intake of folic acid disrupts embryonic development in mice

Birth defects research. A Clinical and molecular teratology, 2011-01, Vol.91 (1), p.8-19

2011

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Genes with Aberrant Expression in Murine Preneoplastic Intestine Show Epigenetic and Expression Changes in Normal Mucosa of Colon Cancer Patients

Cancer prevention research (Philadelphia, Pa.), 2013-11, Vol.6 (11), p.1171-1181

2013

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Low dietary choline and low dietary riboflavin during pregnancy influence reproductive outcomes and heart development in mice

The American journal of clinical nutrition, 2010-04, Vol.91 (4), p.1035-1043

2010

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Strain Differences in Mice Highlight the Role of DNA Damage in Neoplasia Induced by Low Dietary Folate

The Journal of nutrition, 2008-04, Vol.138 (4), p.653-658

2008

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Low dietary folate initiates intestinal tumors in mice, with altered expression of G2-M checkpoint regulators : Polo-like kinase 1 and Cell Division Cycle 25c

Cancer research (Chicago, Ill.), 2006-11, Vol.66 (21), p.10349-10356

2006

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Susceptibility to intestinal tumorigenesis in folate-deficient mice may be influenced by variation in one-carbon metabolism and DNA repair

The Journal of nutritional biochemistry, 2011-11, Vol.22 (11), p.1022-1029

2011

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Studies of methionine cycle intermediates (SAM, SAH), DNA methylation and the impact of folate deficiency on tumor numbers in Min mice

Carcinogenesis (New York), 2002-01, Vol.23 (1), p.61-65

2002

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Impact of Dnmt1 deficiency, with and without low folate diets, on tumor numbers and DNA methylation in Min mice

Carcinogenesis (New York), 2003-01, Vol.24 (1), p.39-45

2003

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Hypoxia-activated XBP1s recruits HDAC2-EZH2 to engage epigenetic suppression of ΔNp63α expression and promote breast cancer metastasis independent of HIF1α

Cell death and differentiation, 2024-04, Vol.31 (4), p.447-459

2024

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High dietary folate in pregnant mice leads to pseudo-MTHFR deficiency and altered methyl metabolism, with embryonic growth delay and short-term memory impairment in offspring

Human molecular genetics, 2017-03, Vol.26 (5), p.888-900

2017

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ApcMin/+ mouse model of colon cancer: Gene expression profiling in tumors

Journal of cellular biochemistry, 2004-12, Vol.93 (6), p.1242-1254

2004

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Genetic and nutritional deficiencies in folate metabolism influence tumorigenicity in APcmin/+ mice

The Journal of nutritional biochemistry, 2007-05, Vol.18 (5), p.305-312

2007

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Mild Methylenetetrahydrofolate Reductase Deficiency Alters Inflammatory and Lipid Pathways in Liver

Molecular nutrition & food research, 2019-02, Vol.63 (3), p.e1801001-n/a

2019

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Quantitative proteomics reveals differentially expressed proteins in murine preneoplastic intestine in a model of intestinal tumorigenesis induced by low dietary folate and MTHFR deficiency

Proteomics (Weinheim), 2014-11, Vol.14 (21-22), p.2558-2565

2014

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Moderate folic acid supplementation and MTHFD1-synthetase deficiency in mice, a model for the R653Q variant, result in embryonic defects and abnormal placental development

The American journal of clinical nutrition, 2016-11, Vol.104 (5), p.1459-1469

2016

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Severe methylenetetrahydrofolate reductase deficiency in mice results in behavioral anomalies with morphological and biochemical changes in hippocampus

Molecular genetics and metabolism, 2012-06, Vol.106 (2), p.149-159

2012

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Differential gene expression and methylation in the retinoid/PPARA pathway and of tumor suppressors may modify intestinal tumorigenesis induced by low folate in mice

Molecular nutrition & food research, 2013-04, Vol.57 (4), p.686-697

2013

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Low Dietary Folate Interacts with MTHFD1 Synthetase Deficiency in Mice, a Model for the R653Q Variant, to Increase Incidence of Developmental Delays and Defects

The Journal of nutrition, 2018-04, Vol.148 (4), p.501-509

2018

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MTHFD1 formyltetrahydrofolate synthetase deficiency, a model for the MTHFD1 R653Q variant, leads to congenital heart defects in mice

Birth defects research. A Clinical and molecular teratology, 2015-12, Vol.103 (12), p.1031-1038

2015

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Mouse model for deficiency of methionine synthase reductase exhibits short-term memory impairment and disturbances in brain choline metabolism

Biochemical journal, 2014-07, Vol.461 (2), p.205-212

2014

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Complete deficiency of methylenetetrahydrofolate reductase in mice is associated with impaired retinal function and variable mortality, hematological profiles, and reproductive outcomes

Journal of inherited metabolic disease, 2011-02, Vol.34 (1), p.147-157

2011

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Murine MTHFD1‐synthetase deficiency, a model for the human MTHFD1 R653Q polymorphism, decreases growth of colorectal tumors

Molecular carcinogenesis, 2017-03, Vol.56 (3), p.1030-1040

2017

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Moderately high intake of folic acid has a negative impact on mouse embryonic development

High folic acid consumption leads to pseudo-MTHFR deficiency, altered lipid metabolism, and liver injury in mice

Steatosis in Mice Is Associated with Gender, Folate Intake, and Expression of Genes of One-Carbon Metabolism

High intake of folic acid disrupts embryonic development in mice

Genes with Aberrant Expression in Murine Preneoplastic Intestine Show Epigenetic and Expression Changes in Normal Mucosa of Colon Cancer Patients

Low dietary choline and low dietary riboflavin during pregnancy influence reproductive outcomes and heart development in mice

Strain Differences in Mice Highlight the Role of DNA Damage in Neoplasia Induced by Low Dietary Folate

Low dietary folate initiates intestinal tumors in mice, with altered expression of G2-M checkpoint regulators : Polo-like kinase 1 and Cell Division Cycle 25c

Susceptibility to intestinal tumorigenesis in folate-deficient mice may be influenced by variation in one-carbon metabolism and DNA repair

Studies of methionine cycle intermediates (SAM, SAH), DNA methylation and the impact of folate deficiency on tumor numbers in Min mice

Impact of Dnmt1 deficiency, with and without low folate diets, on tumor numbers and DNA methylation in Min mice

Hypoxia-activated XBP1s recruits HDAC2-EZH2 to engage epigenetic suppression of ΔNp63α expression and promote breast cancer metastasis independent of HIF1α

High dietary folate in pregnant mice leads to pseudo-MTHFR deficiency and altered methyl metabolism, with embryonic growth delay and short-term memory impairment in offspring

ApcMin/+ mouse model of colon cancer: Gene expression profiling in tumors

Genetic and nutritional deficiencies in folate metabolism influence tumorigenicity in APcmin/+ mice

Mild Methylenetetrahydrofolate Reductase Deficiency Alters Inflammatory and Lipid Pathways in Liver

Quantitative proteomics reveals differentially expressed proteins in murine preneoplastic intestine in a model of intestinal tumorigenesis induced by low dietary folate and MTHFR deficiency

Moderate folic acid supplementation and MTHFD1-synthetase deficiency in mice, a model for the R653Q variant, result in embryonic defects and abnormal placental development

Severe methylenetetrahydrofolate reductase deficiency in mice results in behavioral anomalies with morphological and biochemical changes in hippocampus

Differential gene expression and methylation in the retinoid/PPARA pathway and of tumor suppressors may modify intestinal tumorigenesis induced by low folate in mice

Low Dietary Folate Interacts with MTHFD1 Synthetase Deficiency in Mice, a Model for the R653Q Variant, to Increase Incidence of Developmental Delays and Defects

MTHFD1 formyltetrahydrofolate synthetase deficiency, a model for the MTHFD1 R653Q variant, leads to congenital heart defects in mice

Mouse model for deficiency of methionine synthase reductase exhibits short-term memory impairment and disturbances in brain choline metabolism

Complete deficiency of methylenetetrahydrofolate reductase in mice is associated with impaired retinal function and variable mortality, hematological profiles, and reproductive outcomes

Murine MTHFD1‐synthetase deficiency, a model for the human MTHFD1 R653Q polymorphism, decreases growth of colorectal tumors

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