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Brain high-throughput multi-omics data reveal molecular heterogeneity in Alzheimer's disease

PLoS biology, 2024-04, Vol.22 (4), p.e3002607

2024

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Amyotrophic lateral sclerosis is a distal axonopathy: evidence in mice and man

Experimental neurology, 2004-02, Vol.185 (2), p.232-240

2004

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VCP suppresses proteopathic seeding in neurons

Molecular neurodegeneration, 2022-04, Vol.17 (1), p.30-30, Article 30

2022

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APOE genotype regulates pathology and disease progression in synucleinopathy

Science translational medicine, 2020-02, Vol.12 (529)

2020

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APOE3ch alters microglial response and suppresses Aβ-induced tau seeding and spread

Cell, 2024-01, Vol.187 (2), p.428-445.e20

2024

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An astrocyte BMAL1-BAG3 axis protects against alpha-synuclein and tau pathology

Neuron (Cambridge, Mass.), 2023-08, Vol.111 (15), p.2383-2398.e7

2023

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Deletion of M1 Muscarinic Acetylcholine Receptors Increases Amyloid Pathology In Vitro and In Vivo

The Journal of neuroscience, 2010-03, Vol.30 (12), p.4190-4196

2010

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A Selective Allosteric Potentiator of the M1 Muscarinic Acetylcholine Receptor Increases Activity of Medial Prefrontal Cortical Neurons and Restores Impairments in Reversal Learning

The Journal of neuroscience, 2009-11, Vol.29 (45), p.14271-14286

2009

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A Subpopulation of Neuronal M4 Muscarinic Acetylcholine Receptors Plays a Critical Role in Modulating Dopamine-Dependent Behaviors

The Journal of neuroscience, 2010-02, Vol.30 (6), p.2396-2405

2010

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Neuronal deletion of the circadian clock gene Bmal1 induces cell-autonomous dopaminergic neurodegeneration

JCI insight, 2024-01, Vol.9 (2)

2024

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Calpain inhibition protects against Taxol‐induced sensory neuropathy

Brain (London, England : 1878), 2004-03, Vol.127 (3), p.671-679

2004

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The WldS gene modestly prolongs survival in the SOD1G93A fALS mouse

Neurobiology of disease, 2005-06, Vol.19 (1-2), p.293-300

2005

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Wlds mice are resistant to paclitaxel (taxol) neuropathy

Annals of neurology, 2002-10, Vol.52 (4), p.442-447

2002

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Novel allosteric agonists of M1 muscarinic acetylcholine receptors induce brain region-specific responses that correspond with behavioral effects in animal models

The Journal of neuroscience, 2012-06, Vol.32 (25), p.8532-8544

2012

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The WldS protein protects against axonal degeneration: A model of gene therapy for peripheral neuropathy

Annals of neurology, 2001-12, Vol.50 (6), p.773-779

2001

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NLRX1 Protein Attenuates Inflammatory Responses to Infection by Interfering with the RIG-I-MAVS and TRAF6-NF-κB Signaling Pathways

Immunity (Cambridge, Mass.), 2011-06, Vol.34 (6), p.854-865

2011

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A Core Function for p120-Catenin in Cadherin Turnover

The Journal of cell biology, 2003-11, Vol.163 (3), p.525-534

2003

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p120-Catenin and p190RhoGAP Regulate Cell-Cell Adhesion by Coordinating Antagonism between Rac and Rho

Cell, 2006-12, Vol.127 (5), p.1027-1039

2006

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Blocked Acinar Development, E-Cadherin Reduction, and Intraepithelial Neoplasia upon Ablation of p120-Catenin in the Mouse Salivary Gland

Developmental cell, 2006, Vol.10 (1), p.21-31

2006

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JNK potentiates TNF-stimulated necrosis by increasing the production of cytotoxic reactive oxygen species

Genes & development, 2004-12, Vol.18 (23), p.2905-2915

2004

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The Immune Modulator FTY720 Targets Sphingosine 1-Phosphate Receptors

The Journal of biological chemistry, 2002-06, Vol.277 (24), p.21453-21457

2002

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The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB

Nature immunology, 2012-09, Vol.13 (9), p.823-831

2012

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p120-catenin is essential for maintenance of barrier function and intestinal homeostasis in mice

The Journal of clinical investigation, 2010-06, Vol.120 (6), p.1824-1835

2010

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Acyl-CoA Synthetase 1 Is Induced by Gram-negative Bacteria and Lipopolysaccharide and Is Required for Phospholipid Turnover in Stimulated Macrophages

The Journal of biological chemistry, 2013-04, Vol.288 (14), p.9957-9970

2013

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Vimentin regulates activation of the NLRP3 inflammasome

Nature communications, 2015-03, Vol.6 (1), p.6574-6574, Article 6574

2015

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Brain high-throughput multi-omics data reveal molecular heterogeneity in Alzheimer's disease

Amyotrophic lateral sclerosis is a distal axonopathy: evidence in mice and man

VCP suppresses proteopathic seeding in neurons

APOE genotype regulates pathology and disease progression in synucleinopathy

APOE3ch alters microglial response and suppresses Aβ-induced tau seeding and spread

An astrocyte BMAL1-BAG3 axis protects against alpha-synuclein and tau pathology

Deletion of M1 Muscarinic Acetylcholine Receptors Increases Amyloid Pathology In Vitro and In Vivo

A Selective Allosteric Potentiator of the M1 Muscarinic Acetylcholine Receptor Increases Activity of Medial Prefrontal Cortical Neurons and Restores Impairments in Reversal Learning

A Subpopulation of Neuronal M4 Muscarinic Acetylcholine Receptors Plays a Critical Role in Modulating Dopamine-Dependent Behaviors

Neuronal deletion of the circadian clock gene Bmal1 induces cell-autonomous dopaminergic neurodegeneration

Calpain inhibition protects against Taxol‐induced sensory neuropathy

The WldS gene modestly prolongs survival in the SOD1G93A fALS mouse

Wlds mice are resistant to paclitaxel (taxol) neuropathy

Novel allosteric agonists of M1 muscarinic acetylcholine receptors induce brain region-specific responses that correspond with behavioral effects in animal models

The WldS protein protects against axonal degeneration: A model of gene therapy for peripheral neuropathy

NLRX1 Protein Attenuates Inflammatory Responses to Infection by Interfering with the RIG-I-MAVS and TRAF6-NF-κB Signaling Pathways

A Core Function for p120-Catenin in Cadherin Turnover

p120-Catenin and p190RhoGAP Regulate Cell-Cell Adhesion by Coordinating Antagonism between Rac and Rho

Blocked Acinar Development, E-Cadherin Reduction, and Intraepithelial Neoplasia upon Ablation of p120-Catenin in the Mouse Salivary Gland

JNK potentiates TNF-stimulated necrosis by increasing the production of cytotoxic reactive oxygen species

The Immune Modulator FTY720 Targets Sphingosine 1-Phosphate Receptors

The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB

p120-catenin is essential for maintenance of barrier function and intestinal homeostasis in mice

Acyl-CoA Synthetase 1 Is Induced by Gram-negative Bacteria and Lipopolysaccharide and Is Required for Phospholipid Turnover in Stimulated Macrophages

Vimentin regulates activation of the NLRP3 inflammasome

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