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Deficiency of thyroid hormone receptor protects retinal pigment epithelium and photoreceptors from cell death in a mouse model of age-related macular degeneration

Cell death & disease, 2022-03, Vol.13 (3), p.255-255, Article 255

2022

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Potential contribution of ryanodine receptor 2 upregulation to cGMP/PKG signaling‐induced cone degeneration in cyclic nucleotide‐gated channel deficiency

The FASEB journal, 2020-05, Vol.34 (5), p.6335-6350

2020

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Inhibition of thyroid hormone receptor locally in the retina is a therapeutic strategy for retinal degeneration

The FASEB journal, 2017-08, Vol.31 (8), p.3425-3438

2017

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cGMP accumulation causes photoreceptor degeneration in CNG channel deficiency: evidence of cGMP cytotoxicity independently of enhanced CNG channel function

The Journal of neuroscience, 2013-09, Vol.33 (37), p.14939-14948

2013

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The cGMP-Dependent Protein Kinase 2 Contributes to Cone Photoreceptor Degeneration in the Cnga3 -Deficient Mouse Model of Achromatopsia

International journal of molecular sciences, 2020-12, Vol.22 (1), p.52

2020

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cGMP/Protein Kinase G Signaling Suppresses Inositol 1,4,5-Trisphosphate Receptor Phosphorylation and Promotes Endoplasmic Reticulum Stress in Photoreceptors of Cyclic Nucleotide-gated Channel-deficient Mice

The Journal of biological chemistry, 2015-08, Vol.290 (34), p.20880-20892

2015

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Endoplasmic Reticulum Stress-associated Cone Photoreceptor Degeneration in Cyclic Nucleotide-gated Channel Deficiency

The Journal of biological chemistry, 2012-05, Vol.287 (22), p.18018-18029

2012

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Ocular delivery of compacted DNA-nanoparticles does not elicit toxicity in the mouse retina

PloS one, 2009-10, Vol.4 (10), p.e7410-e7410

2009

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Expression of Cone-Photoreceptor-Specific Antigens in a Cell Line Derived from Retinal Tumors in Transgenic Mice

Investigative ophthalmology & visual science, 2004-03, Vol.45 (3), p.764-768

2004

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Early-onset, slow progression of cone photoreceptor dysfunction and degeneration in CNG channel subunit CNGB3 deficiency

Investigative ophthalmology & visual science, 2011-05, Vol.52 (6), p.3557-3566

2011

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Loss of cone cyclic nucleotide-gated channel leads to alterations in light response modulating system and cellular stress response pathways: a gene expression profiling study

Human molecular genetics, 2013-10, Vol.22 (19), p.3906-3919

2013

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Differential requirements for retinal degeneration slow intermolecular disulfide-linked oligomerization in rods versus cones

Human molecular genetics, 2009-03, Vol.18 (5), p.797-808

2009

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Inhibition of Ryanodine Receptor 1 Reduces Endoplasmic Reticulum (ER) Stress and Promotes ER Protein Degradation in Cyclic Nucleotide-Gated Channel Deficiency

Advances in experimental medicine and biology, 2023, Vol.1415, p.353-358

2023

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Native cone photoreceptor cyclic nucleotide-gated channel is a heterotetrameric complex comprising both CNGA3 and CNGB3: a study using the cone-dominant retina of Nrl-/- mice

Journal of neurochemistry, 2008-09, Vol.106 (5), p.2042-2055

2008

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Excessive Thyroid Hormone Signaling Induces Photoreceptor Degeneration in Mice

eNeuro, 2023-09, Vol.10 (9), p.ENEURO.0058-23.2023

2023

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Accessory heterozygous mutations in cone photoreceptor CNGA3 exacerbate CNG channel-associated retinopathy

The Journal of clinical investigation, 2018-12, Vol.128 (12), p.5663-5675

2018

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Role of the Second Intradiscal Loop of Peripherin/rds in Homo and Hetero Associations

Biochemistry (Easton), 2005-03, Vol.44 (12), p.4897-4904

2005

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Overexpression of Type 3 Iodothyronine Deiodinase Reduces Cone Death in the Leber Congenital Amaurosis Model Mice

Advances in experimental medicine and biology, 2018, Vol.1074, p.125-131

2018

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Impaired cone function and cone degeneration resulting from CNGB3 deficiency: down-regulation of CNGA3 biosynthesis as a potential mechanism

Human molecular genetics, 2009-12, Vol.18 (24), p.4770-4780

2009

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Vitreal delivery of AAV vectored Cnga3 restores cone function in CNGA3-/-/Nrl-/- mice, an all-cone model of CNGA3 achromatopsia

Human molecular genetics, 2015-07, Vol.24 (13), p.3699-3707

2015

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Outer Segment Oligomerization of Rds: Evidence from Mouse Models and Subcellular Fractionation

Biochemistry (Easton), 2008-01, Vol.47 (4), p.1144-1156

2008

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Exploration of cone cyclic nucleotide-gated channel-interacting proteins using affinity purification and mass spectrometry

Advances in experimental medicine and biology, 2014, Vol.801, p.57

2014

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CNGA3 deficiency affects cone synaptic terminal structure and function and leads to secondary rod dysfunction and degeneration

Investigative ophthalmology & visual science, 2012-03, Vol.53 (3), p.1117-1129

2012

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Cones respond to light in the absence of transducin β subunit

The Journal of neuroscience, 2013-03, Vol.33 (12), p.5182-5194

2013

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The B3 Subunit of the Cone Cyclic Nucleotide-gated Channel Regulates the Light Responses of Cones and Contributes to the Channel Structural Flexibility

The Journal of biological chemistry, 2016-04, Vol.291 (16), p.8721-8734

2016

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Deficiency of thyroid hormone receptor protects retinal pigment epithelium and photoreceptors from cell death in a mouse model of age-related macular degeneration

Potential contribution of ryanodine receptor 2 upregulation to cGMP/PKG signaling‐induced cone degeneration in cyclic nucleotide‐gated channel deficiency

Inhibition of thyroid hormone receptor locally in the retina is a therapeutic strategy for retinal degeneration

cGMP accumulation causes photoreceptor degeneration in CNG channel deficiency: evidence of cGMP cytotoxicity independently of enhanced CNG channel function

The cGMP-Dependent Protein Kinase 2 Contributes to Cone Photoreceptor Degeneration in the Cnga3 -Deficient Mouse Model of Achromatopsia

cGMP/Protein Kinase G Signaling Suppresses Inositol 1,4,5-Trisphosphate Receptor Phosphorylation and Promotes Endoplasmic Reticulum Stress in Photoreceptors of Cyclic Nucleotide-gated Channel-deficient Mice

Endoplasmic Reticulum Stress-associated Cone Photoreceptor Degeneration in Cyclic Nucleotide-gated Channel Deficiency

Ocular delivery of compacted DNA-nanoparticles does not elicit toxicity in the mouse retina

Expression of Cone-Photoreceptor-Specific Antigens in a Cell Line Derived from Retinal Tumors in Transgenic Mice

Early-onset, slow progression of cone photoreceptor dysfunction and degeneration in CNG channel subunit CNGB3 deficiency

Loss of cone cyclic nucleotide-gated channel leads to alterations in light response modulating system and cellular stress response pathways: a gene expression profiling study

Differential requirements for retinal degeneration slow intermolecular disulfide-linked oligomerization in rods versus cones

Inhibition of Ryanodine Receptor 1 Reduces Endoplasmic Reticulum (ER) Stress and Promotes ER Protein Degradation in Cyclic Nucleotide-Gated Channel Deficiency

Native cone photoreceptor cyclic nucleotide-gated channel is a heterotetrameric complex comprising both CNGA3 and CNGB3: a study using the cone-dominant retina of Nrl-/- mice

Excessive Thyroid Hormone Signaling Induces Photoreceptor Degeneration in Mice

Accessory heterozygous mutations in cone photoreceptor CNGA3 exacerbate CNG channel-associated retinopathy

Role of the Second Intradiscal Loop of Peripherin/rds in Homo and Hetero Associations

Overexpression of Type 3 Iodothyronine Deiodinase Reduces Cone Death in the Leber Congenital Amaurosis Model Mice

Impaired cone function and cone degeneration resulting from CNGB3 deficiency: down-regulation of CNGA3 biosynthesis as a potential mechanism

Vitreal delivery of AAV vectored Cnga3 restores cone function in CNGA3-/-/Nrl-/- mice, an all-cone model of CNGA3 achromatopsia

Outer Segment Oligomerization of Rds: Evidence from Mouse Models and Subcellular Fractionation

Exploration of cone cyclic nucleotide-gated channel-interacting proteins using affinity purification and mass spectrometry

CNGA3 deficiency affects cone synaptic terminal structure and function and leads to secondary rod dysfunction and degeneration

Cones respond to light in the absence of transducin β subunit

The B3 Subunit of the Cone Cyclic Nucleotide-gated Channel Regulates the Light Responses of Cones and Contributes to the Channel Structural Flexibility

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