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Genetics and development of neural tube defects

The Journal of pathology, 2010-01, Vol.220 (2), p.217-230

2010

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The relationship between sonic Hedgehog signaling, cilia, and neural tube defects

Birth defects research. A Clinical and molecular teratology, 2010-08, Vol.88 (8), p.633-652

2010

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Cell non-autonomy amplifies disruption of neurulation by mosaic Vangl2 deletion in mice

Nature communications, 2021-02, Vol.12 (1), p.1159-17, Article 1159

2021

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Glycine decarboxylase deficiency causes neural tube defects and features of non-ketotic hyperglycinemia in mice

Nature communications, 2015-03, Vol.6 (1), p.6388-6388, Article 6388

2015

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Hindbrain neuropore tissue geometry determines asymmetric cell-mediated closure dynamics in mouse embryos

Proceedings of the National Academy of Sciences - PNAS, 2021-05, Vol.118 (19), p.1

2021

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Neural tube defects-disorders of neurulation and related embryonic processes

Wiley interdisciplinary reviews. Developmental biology, 2013-03, Vol.2 (2), p.213-227

2013

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Rho-kinase-dependent actin turnover and actomyosin disassembly are necessary for mouse spinal neural tube closure

Journal of cell science, 2015-07, Vol.128 (14), p.2468-2481

2015

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Spinal neural tube closure depends on regulation of surface ectoderm identity and biomechanics by Grhl2

Nature communications, 2019-06, Vol.10 (1), p.2487-2487, Article 2487

2019

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Neurulation in the cranial region – normal and abnormal

Journal of anatomy, 2005-11, Vol.207 (5), p.623-635

Copp, Andrew J.

2005

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Convergent extension, planar-cell-polarity signalling and initiation of mouse neural tube closure

Development (Cambridge), 2007-02, Vol.134 (4), p.789-799

2007

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Knockout of the PKN Family of Rho Effector Kinases Reveals a Non-redundant Role for PKN2 in Developmental Mesoderm Expansion

Cell reports (Cambridge), 2016-01, Vol.14 (3), p.440-448

2016

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Novel mouse model of encephalocele: post-neurulation origin and relationship to open neural tube defects

Disease models & mechanisms, 2019-11, Vol.12 (11)

2019

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Vangl2-environment interaction causes severe neural tube defects, without abnormal neuroepithelial convergent extension

Disease models & mechanisms, 2022-01, Vol.15 (1)

2022

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Inositol, neural tube closure and the prevention of neural tube defects

Birth defects research, 2017-01, Vol.109 (2), p.68-80

2017

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Mutations in genes encoding the glycine cleavage system predispose to neural tube defects in mice and humans

Human molecular genetics, 2012-04, Vol.21 (7), p.1496-1503

2012

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Fetal spina bifida in a mouse model: loss of neural function in utero

Journal of neurosurgery, 2007-03, Vol.106 (3 Suppl), p.213-221

2007

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Regulation of cell protrusions by small GTPases during fusion of the neural folds

eLife, 2016-04, Vol.5, p.e13273-e13273

2016

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Genetic interactions between planar cell polarity genes cause diverse neural tube defects in mice

Disease models & mechanisms, 2014-10, Vol.7 (10), p.1153-1163

2014

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Mutation of Celsr1 Disrupts Planar Polarity of Inner Ear Hair Cells and Causes Severe Neural Tube Defects in the Mouse

Current biology, 2003-07, Vol.13 (13), p.1129-1133

2003

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Cellular mechanisms underlying Pax3- related neural tube defects and their prevention by folic acid

Disease models & mechanisms, 2019-11, Vol.12 (11)

2019

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Lamin b1 polymorphism influences morphology of the nuclear envelope, cell cycle progression, and risk of neural tube defects in mice

PLoS genetics, 2012-11, Vol.8 (11), p.e1003059-e1003059

2012

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Neural plate morphogenesis during mouse neurulation is regulated by antagonism of Bmp signalling

Development (Cambridge), 2007-09, Vol.134 (17), p.3203-3211

2007

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In vivo genetic ablation by Cre-mediated expression of diphtheria toxin fragment A

Genesis (New York, N.Y. : 2000), 2005-11, Vol.43 (3), p.129-135

2005

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Apoptosis is not required for mammalian neural tube closure

Proceedings of the National Academy of Sciences - PNAS, 2009-05, Vol.106 (20), p.8233-8238

2009

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Mouse models of neural tube defects: Investigating preventive mechanisms

American journal of medical genetics. Part C, Seminars in medical genetics, 2005-05, Vol.135C (1), p.31-41

2005

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Genetics and development of neural tube defects

The relationship between sonic Hedgehog signaling, cilia, and neural tube defects

Cell non-autonomy amplifies disruption of neurulation by mosaic Vangl2 deletion in mice

Glycine decarboxylase deficiency causes neural tube defects and features of non-ketotic hyperglycinemia in mice

Hindbrain neuropore tissue geometry determines asymmetric cell-mediated closure dynamics in mouse embryos

Neural tube defects-disorders of neurulation and related embryonic processes

Rho-kinase-dependent actin turnover and actomyosin disassembly are necessary for mouse spinal neural tube closure

Spinal neural tube closure depends on regulation of surface ectoderm identity and biomechanics by Grhl2

Neurulation in the cranial region – normal and abnormal

Convergent extension, planar-cell-polarity signalling and initiation of mouse neural tube closure

Knockout of the PKN Family of Rho Effector Kinases Reveals a Non-redundant Role for PKN2 in Developmental Mesoderm Expansion

Novel mouse model of encephalocele: post-neurulation origin and relationship to open neural tube defects

Vangl2-environment interaction causes severe neural tube defects, without abnormal neuroepithelial convergent extension

Inositol, neural tube closure and the prevention of neural tube defects

Mutations in genes encoding the glycine cleavage system predispose to neural tube defects in mice and humans

Fetal spina bifida in a mouse model: loss of neural function in utero

Regulation of cell protrusions by small GTPases during fusion of the neural folds

Genetic interactions between planar cell polarity genes cause diverse neural tube defects in mice

Mutation of Celsr1 Disrupts Planar Polarity of Inner Ear Hair Cells and Causes Severe Neural Tube Defects in the Mouse

Cellular mechanisms underlying Pax3- related neural tube defects and their prevention by folic acid

Lamin b1 polymorphism influences morphology of the nuclear envelope, cell cycle progression, and risk of neural tube defects in mice

Neural plate morphogenesis during mouse neurulation is regulated by antagonism of Bmp signalling

In vivo genetic ablation by Cre-mediated expression of diphtheria toxin fragment A

Apoptosis is not required for mammalian neural tube closure

Mouse models of neural tube defects: Investigating preventive mechanisms

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