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Apoptotic Caspases Suppress mtDNA-Induced STING-Mediated Type I IFN Production

Cell, 2014-12, Vol.159 (7), p.1549-1562

2014

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Therapeutic Response to Non-genotoxic Activation of p53 by Nutlin3a Is Driven by PUMA-Mediated Apoptosis in Lymphoma Cells

Cell reports (Cambridge), 2016-03, Vol.14 (8), p.1858-1866

2016

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Proapoptotic BH3-Only Protein Bid Is Essential For Death Receptor–Induced Apoptosis of Pancreatic β-Cells

Diabetes (New York, N.Y.), 2008-05, Vol.57 (5), p.1284-1292

2008

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XIAP discriminates between type I and type II FAS-induced apoptosis

Nature (London), 2009-08, Vol.460 (7258), p.1035-1039

2009

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A Cluster of Interferon-γ-Inducible p65 GTPases Plays a Critical Role in Host Defense against Toxoplasma gondii

Immunity (Cambridge, Mass.), 2012-08, Vol.37 (2), p.302-313

2012

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The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized

Cancer cell, 2006-11, Vol.10 (5), p.389-399

2006

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Glucose Induces Pancreatic Islet Cell Apoptosis That Requires the BH3-Only Proteins Bim and Puma and Multi-BH Domain Protein Bax

Diabetes (New York, N.Y.), 2010-03, Vol.59 (3), p.644-652

2010

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The BH3-Only Protein Bid Is Dispensable for DNA Damage- and Replicative Stress-Induced Apoptosis or Cell-Cycle Arrest

Cell, 2007-04, Vol.129 (2), p.423-433

2007

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The Proapoptotic BH3-Only Protein Bim Is Expressed in Hematopoietic, Epithelial, Neuronal, and Germ Cells

The American journal of pathology, 2000-08, Vol.157 (2), p.449-461

2000

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Mesenchymal stromal cell apoptosis is required for their therapeutic function

Nature communications, 2021-11, Vol.12 (1), p.6495-6495, Article 6495

2021

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Anti-apoptotic proteins BCL-2, MCL-1 and A1 summate collectively to maintain survival of immune cell populations both in vitro and in vivo

Cell death and differentiation, 2017-05, Vol.24 (5), p.878-888

2017

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PRMT1-mediated H4R3me2a recruits SMARCA4 to promote colorectal cancer progression by enhancing EGFR signaling

Genome medicine, 2021-04, Vol.13 (1), p.58-58, Article 58

2021

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Bcl-xL–inhibitory BH3 mimetics can induce a transient thrombocytopathy that undermines the hemostatic function of platelets

Blood, 2011-08, Vol.118 (6), p.1663-1674

2011

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Targeting of MCL-1 kills MYC-driven mouse and human lymphomas even when they bear mutations in p53

Genes & development, 2014-01, Vol.28 (1), p.58-70

2014

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EBV BCL-2 homologue BHRF1 drives chemoresistance and lymphomagenesis by inhibiting multiple cellular pro-apoptotic proteins

Cell death and differentiation, 2020-05, Vol.27 (5), p.1554-1568

2020

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Identification of an activation site in Bak and mitochondrial Bax triggered by antibodies

Nature communications, 2016-05, Vol.7 (1), p.11734-10, Article 11734

2016

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Megakaryocytes possess a functional intrinsic apoptosis pathway that must be restrained to survive and produce platelets

The Journal of experimental medicine, 2011-09, Vol.208 (10), p.2017-2031

2011

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A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production

Nature communications, 2015-03, Vol.6 (1), p.6442-6442, Article 6442

2015

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The Dendritic Cell Receptor Clec9A Binds Damaged Cells via Exposed Actin Filaments

Immunity (Cambridge, Mass.), 2012-04, Vol.36 (4), p.646-657

2012

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Bcl‐2 Antagonists Kill Plasmacytoid Dendritic Cells From Lupus‐Prone Mice and Dampen Interferon‐α Production

Arthritis & rheumatology (Hoboken, N.J.), 2015-03, Vol.67 (3), p.797-808

2015

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Caspase-9 mediates the apoptotic death of megakaryocytes and platelets, but is dispensable for their generation and function

Blood, 2012-05, Vol.119 (18), p.4283-4290

2012

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In vivo Efficacy of the Bcl-2 Antagonist ABT-737 against Aggressive Myc-Driven Lymphomas

Proceedings of the National Academy of Sciences - PNAS, 2008-11, Vol.105 (46), p.17961-17966

2008

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Prosurvival Bcl-2 family members reveal a distinct apoptotic identity between conventional and plasmacytoid dendritic cells

Proceedings of the National Academy of Sciences - PNAS, 2015-03, Vol.112 (13), p.4044-4049

2015

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A Novel BH3 Ligand That Selectively Targets Mcl-1 Reveals That Apoptosis Can Proceed without Mcl-1 Degradation

The Journal of cell biology, 2008-01, Vol.180 (2), p.341-355

2008

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BH3 mimetics antagonizing restricted prosurvival Bcl-2 proteins represent another class of selective immune modulatory drugs

Proceedings of the National Academy of Sciences - PNAS, 2010-06, Vol.107 (24), p.10967-10971

2010

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Apoptotic Caspases Suppress mtDNA-Induced STING-Mediated Type I IFN Production

Therapeutic Response to Non-genotoxic Activation of p53 by Nutlin3a Is Driven by PUMA-Mediated Apoptosis in Lymphoma Cells

Proapoptotic BH3-Only Protein Bid Is Essential For Death Receptor–Induced Apoptosis of Pancreatic β-Cells

XIAP discriminates between type I and type II FAS-induced apoptosis

A Cluster of Interferon-γ-Inducible p65 GTPases Plays a Critical Role in Host Defense against Toxoplasma gondii

The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized

Glucose Induces Pancreatic Islet Cell Apoptosis That Requires the BH3-Only Proteins Bim and Puma and Multi-BH Domain Protein Bax

The BH3-Only Protein Bid Is Dispensable for DNA Damage- and Replicative Stress-Induced Apoptosis or Cell-Cycle Arrest

The Proapoptotic BH3-Only Protein Bim Is Expressed in Hematopoietic, Epithelial, Neuronal, and Germ Cells

Mesenchymal stromal cell apoptosis is required for their therapeutic function

Anti-apoptotic proteins BCL-2, MCL-1 and A1 summate collectively to maintain survival of immune cell populations both in vitro and in vivo

PRMT1-mediated H4R3me2a recruits SMARCA4 to promote colorectal cancer progression by enhancing EGFR signaling

Bcl-xL–inhibitory BH3 mimetics can induce a transient thrombocytopathy that undermines the hemostatic function of platelets

Targeting of MCL-1 kills MYC-driven mouse and human lymphomas even when they bear mutations in p53

EBV BCL-2 homologue BHRF1 drives chemoresistance and lymphomagenesis by inhibiting multiple cellular pro-apoptotic proteins

Identification of an activation site in Bak and mitochondrial Bax triggered by antibodies

Megakaryocytes possess a functional intrinsic apoptosis pathway that must be restrained to survive and produce platelets

A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production

The Dendritic Cell Receptor Clec9A Binds Damaged Cells via Exposed Actin Filaments

Bcl‐2 Antagonists Kill Plasmacytoid Dendritic Cells From Lupus‐Prone Mice and Dampen Interferon‐α Production

Caspase-9 mediates the apoptotic death of megakaryocytes and platelets, but is dispensable for their generation and function

In vivo Efficacy of the Bcl-2 Antagonist ABT-737 against Aggressive Myc-Driven Lymphomas

Prosurvival Bcl-2 family members reveal a distinct apoptotic identity between conventional and plasmacytoid dendritic cells

A Novel BH3 Ligand That Selectively Targets Mcl-1 Reveals That Apoptosis Can Proceed without Mcl-1 Degradation

BH3 mimetics antagonizing restricted prosurvival Bcl-2 proteins represent another class of selective immune modulatory drugs

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