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Role of DNA Mismatch Repair Defects in the Pathogenesis of Human Cancer

Journal of clinical oncology, 2003-03, Vol.21 (6), p.1174-1179

Päivi Peltomäki

2003

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Ten Years After Mutation Testing for Lynch Syndrome: Cancer Incidence and Outcome in Mutation-Positive and Mutation-Negative Family Members

Journal of clinical oncology, 2009-10, Vol.27 (28), p.4793-4797

2009

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Lynch Syndrome (Hereditary Nonpolyposis Colorectal Cancer) Diagnostics

JNCI : Journal of the National Cancer Institute, 2007-02, Vol.99 (4), p.291-299

2007

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p53 Codon 72 and MDM2 SNP309 Polymorphisms and Age of Colorectal Cancer Onset in Lynch Syndrome

Clinical cancer research, 2005-10, Vol.11 (19), p.6840-6844

2005

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Controlled 15-year trial on screening for colorectal cancer in families with hereditary nonpolyposis colorectal cancer

Gastroenterology (New York, N.Y. 1943), 2000-05, Vol.118 (5), p.829-834

2000

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Molecular Analysis of Endometrial Tumorigenesis: Importance of Complex Hyperplasia Regardless of Atypia

Clinical cancer research, 2009-09, Vol.15 (18), p.5772-5783

2009

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Distinct molecular profiles in Lynch syndrome‐associated and sporadic ovarian carcinomas

International journal of cancer, 2013-12, Vol.133 (11), p.2596-2608

2013

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Genetic and Epigenetic Modification of MLH1 Accounts for a Major Share of Microsatellite-Unstable Colorectal Cancers

The American journal of pathology, 2000-05, Vol.156 (5), p.1773-1779

2000

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Patterns of PIK3CA alterations in familial colorectal and endometrial carcinoma

International journal of cancer, 2007-08, Vol.121 (4), p.915-920

2007

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PTEN Mutational Spectra, Expression Levels, and Subcellular Localization in Microsatellite Stable and Unstable Colorectal Cancers

The American journal of pathology, 2002-08, Vol.161 (2), p.439-447

2002

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The genetics of HNPCC: Application to diagnosis and screening

Critical reviews in oncology/hematology, 2006-06, Vol.58 (3), p.208-220

2006

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Distinct Genetic and Epigenetic Signatures of Colorectal Cancers According to Ethnic Origin

Cancer epidemiology, biomarkers & prevention, 2012, Vol.21 (1), p.202-211

2012

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Molecular Analysis of Familial Endometrial Carcinoma: A Manifestation of Hereditary Nonpolyposis Colorectal Cancer or a Separate Syndrome?

Journal of clinical oncology, 2005-07, Vol.23 (21), p.4609-4616

2005

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CYCLIN D1 as a genetic modifier in hereditary nonpolyposis colorectal cancer

Cancer research (Chicago, Ill.), 2001-08, Vol.61 (16), p.6042-6045

2001

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3'-UTR Poly(T/U) Tract Deletions and Altered Expression of EWSR1 Are a Hallmark of Mismatch Repair―Deficient Cancers

Cancer research (Chicago, Ill.), 2014, Vol.74 (1), p.224-234

2014

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Comprehensive characterization of HNPCC-related colorectal cancers reveals striking molecular features in families with no germline mismatch repair gene mutations

Oncogene, 2005-02, Vol.24 (9), p.1542-1551

2005

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Clinicopathological Characterization and Genomic Aberrations in Subcutaneous Panniculitis-Like T-Cell Lymphoma

Journal of investigative dermatology, 2008-09, Vol.128 (9), p.2304-2309

2008

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Altered Expression of MLH1, MSH2, and MSH6 in Predisposition to Hereditary Nonpolyposis Colorectal Cancer

Journal of clinical oncology, 2003-10, Vol.21 (19), p.3629-3637

2003

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Adenomatous Polyposis Families That Screen APC Mutation–Negative by Conventional Methods Are Genetically Heterogeneous

Journal of clinical oncology, 2005-08, Vol.23 (24), p.5651-5659

2005

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Truncation of MBD4 predisposes to reciprocal chromosomal translocations and alters the response to therapeutic agents in colon cancer cells

DNA repair, 2008-02, Vol.7 (2), p.321-328

2008

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Endometrial and Colorectal Tumors from Patients with Hereditary Nonpolyposis Colon Cancer Display Different Patterns of Microsatellite Instability

The American journal of pathology, 2002-06, Vol.160 (6), p.1953-1958

2002

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Loss of the wild type MLH1 gene is a feature of hereditary nonpolyposis colorectal cancer

Nature genetics, 1994-12, Vol.8 (4), p.405-410

1994

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Pathogenicity of the hereditary colorectal cancer mutation hMLH1 del616 linked to shortage of the functional protein

Gastroenterology (New York, N.Y. 1943), 2003-08, Vol.125 (2), p.501-509

2003

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DNA copy number changes in malignant ovarian germ cell tumors

Cancer research (Chicago, Ill.), 2000-06, Vol.60 (11), p.3025-3030

2000

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Role of DNA Mismatch Repair Defects in the Pathogenesis of Human Cancer

Ten Years After Mutation Testing for Lynch Syndrome: Cancer Incidence and Outcome in Mutation-Positive and Mutation-Negative Family Members

Lynch Syndrome (Hereditary Nonpolyposis Colorectal Cancer) Diagnostics

p53 Codon 72 and MDM2 SNP309 Polymorphisms and Age of Colorectal Cancer Onset in Lynch Syndrome

Controlled 15-year trial on screening for colorectal cancer in families with hereditary nonpolyposis colorectal cancer

Molecular Analysis of Endometrial Tumorigenesis: Importance of Complex Hyperplasia Regardless of Atypia

Distinct molecular profiles in Lynch syndrome‐associated and sporadic ovarian carcinomas

Genetic and Epigenetic Modification of MLH1 Accounts for a Major Share of Microsatellite-Unstable Colorectal Cancers

Patterns of PIK3CA alterations in familial colorectal and endometrial carcinoma

PTEN Mutational Spectra, Expression Levels, and Subcellular Localization in Microsatellite Stable and Unstable Colorectal Cancers

The genetics of HNPCC: Application to diagnosis and screening

Distinct Genetic and Epigenetic Signatures of Colorectal Cancers According to Ethnic Origin

Molecular Analysis of Familial Endometrial Carcinoma: A Manifestation of Hereditary Nonpolyposis Colorectal Cancer or a Separate Syndrome?

CYCLIN D1 as a genetic modifier in hereditary nonpolyposis colorectal cancer

3'-UTR Poly(T/U) Tract Deletions and Altered Expression of EWSR1 Are a Hallmark of Mismatch Repair―Deficient Cancers

Comprehensive characterization of HNPCC-related colorectal cancers reveals striking molecular features in families with no germline mismatch repair gene mutations

Clinicopathological Characterization and Genomic Aberrations in Subcutaneous Panniculitis-Like T-Cell Lymphoma

Altered Expression of MLH1, MSH2, and MSH6 in Predisposition to Hereditary Nonpolyposis Colorectal Cancer

Adenomatous Polyposis Families That Screen APC Mutation–Negative by Conventional Methods Are Genetically Heterogeneous

Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer

Truncation of MBD4 predisposes to reciprocal chromosomal translocations and alters the response to therapeutic agents in colon cancer cells

Endometrial and Colorectal Tumors from Patients with Hereditary Nonpolyposis Colon Cancer Display Different Patterns of Microsatellite Instability

Loss of the wild type MLH1 gene is a feature of hereditary nonpolyposis colorectal cancer

Pathogenicity of the hereditary colorectal cancer mutation hMLH1 del616 linked to shortage of the functional protein

DNA copy number changes in malignant ovarian germ cell tumors

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