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Characterization of metabolites and cytochrome P450 isoforms involved in the microsomal metabolism of aconitine

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2006-12, Vol.844 (2), p.292-300

2006

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Brain Drug-Metabolizing Cytochrome P450 Enzymes are Active In Vivo, Demonstrated by Mechanism-Based Enzyme Inhibition

Neuropsychopharmacology (New York, N.Y.), 2009-02, Vol.34 (3), p.634-640

2009

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Developmental triclosan exposure decreases maternal, fetal, and early neonatal thyroxine: A dynamic and kinetic evaluation of a putative mode-of-action

Toxicology (Amsterdam), 2012-10, Vol.300 (1-2), p.31-45

2012

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Inhibitory effects of a dietary phytochemical 3,3′-diindolylmethane on the phenobarbital-induced hepatic CYP mRNA expression and CYP-catalyzed reactions in female rats

Food and chemical toxicology, 2008-07, Vol.46 (7), p.2451-2458

2008

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Sex differences in subacute toxicity and hepatic microsomal metabolism of triptolide in rats

Toxicology (Amsterdam), 2010-04, Vol.271 (1), p.57-63

2010

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Proteasome-dependent degradation of cytochromes P450 2E1 and 2B1 expressed in tetracycline-regulated HeLa cells

Toxicology and applied pharmacology, 2004-09, Vol.199 (3), p.332-343

2004

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Modification by curcumin of mutagenic activation of carcinogenic N‐nitrosamines by extrahepatic cytochromes P‐450 2B1 and 2E1 in rats

Cancer science, 2006-09, Vol.97 (9), p.896-904

2006

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Angiotensin II–Induced Vascular Smooth Muscle Cell Migration and Growth Are Mediated by Cytochrome P450 1B1–Dependent Superoxide Generation

Hypertension (Dallas, Tex. 1979), 2010-06, Vol.55 (6), p.1461-1467

2010

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Role for mitogen-activated protein kinases in phenobarbital-induced expression of cytochrome P450 2B in primary cultures of rat hepatocytes

Toxicology letters, 2006-02, Vol.161 (1), p.61-72

2006

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A mechanism-based integrated pharmacokinetic enzyme model describing the time course and magnitude of phenobarbital-mediated enzyme induction in the rat

Pharmaceutical research, 2006-03, Vol.23 (3), p.521-532

2006

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Effects of short-term in vivo exposure to polybrominated diphenyl ethers on thyroid hormones and hepatic enzyme activities in weanling rats

Toxicological sciences, 2001-05, Vol.61 (1), p.76-82

2001

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A technical mixture of 2,2′,4,4′-tetrabromo diphenyl ether (BDE47) and brominated furans triggers aryl hydrocarbon receptor (AhR) mediated gene expression and toxicity

Chemosphere (Oxford), 2008-09, Vol.73 (2), p.209-215

2008

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Induction of CYP2B1/2 and nicotine metabolism by ethanol in rat liver but not rat brain

Biochemical pharmacology, 2001-10, Vol.62 (8), p.1025-1036

2001

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Effect of naturally occurring plant phenolics on the induction of drug metabolizing enzymes by o-toluidine

Toxicology (Amsterdam), 2003-04, Vol.186 (1), p.67-77

2003

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Cytochrome P450 gene induction in rats ex vivo assessed by quantitative real-time reverse transcriptase-polymerase chain reaction (TaqMan)

Drug metabolism and disposition, 2006-06, Vol.34 (6), p.1063-1069

2006

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Homology modeling and molecular dynamics of CYP1A1 and CYP2B1 to explore the metabolism of aryl derivatives by docking and experimental assays

European journal of medicinal chemistry, 2010-11, Vol.45 (11), p.4845-4855

2010

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N-Nitrosodiethylamine genotoxicity in primary rat hepatocytes: Effects of cytochrome P450 induction by phenobarbital

Toxicology letters, 2011-10, Vol.206 (2), p.139-143

2011

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Cytochrome-P450 2B1 gene silencing attenuates puromycin aminonucleoside-induced cytotoxicity in glomerular epithelial cells

Kidney international, 2010-07, Vol.78 (2), p.182-190

2010

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Different profiles of hepatic alkoxyresorufin O-dealkylase activities in small rodents

Journal of applied toxicology, 2012-12, Vol.32 (12), p.1002-1007

2012

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Green tea extract increases cyclophosphamide-induced teratogenesis by modulating the expression of cytochrome P-450 mRNA

Reproductive toxicology (Elmsford, N.Y.), 2009, Vol.27 (1), p.79-84

2009

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Cancer Prevention Mediated by Caffeic Acid Phenethyl Ester Involves Cyp2b1/2 Modulation in Hepatocarcinogenesis

Toxicologic pathology, 2012-04, Vol.40 (3), p.466-472

2012

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Overexpression of cerebral and hepatic cytochrome P450s alters behavioral activity of rat offspring following prenatal exposure to lindane

Toxicology and applied pharmacology, 2007-12, Vol.225 (3), p.278-292

2007

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Piperine inhibits aflatoxin B1-induced cytotoxicity and genotoxicity in V79 Chinese hamster cells genetically engineered to express rat cytochrome P4502B1

Journal of ethnopharmacology, 1997-11, Vol.58 (3), p.165-173

1997

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Differential effects of oltipraz on CYP1A and CYP2B in rat lung

Carcinogenesis (New York), 2001-01, Vol.22 (1), p.49-55

2001

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Promoting effects of monomethylarsonic acid, dimethylarsinic acid and trimethylarsine oxide on induction of rat liver preneoplastic glutathione S‐transferase placental form positive foci: A possible reactive oxygen species mechanism

International journal of cancer, 2002-07, Vol.100 (2), p.136-139

2002

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Characterization of metabolites and cytochrome P450 isoforms involved in the microsomal metabolism of aconitine

Brain Drug-Metabolizing Cytochrome P450 Enzymes are Active In Vivo, Demonstrated by Mechanism-Based Enzyme Inhibition

Developmental triclosan exposure decreases maternal, fetal, and early neonatal thyroxine: A dynamic and kinetic evaluation of a putative mode-of-action

Inhibitory effects of a dietary phytochemical 3,3′-diindolylmethane on the phenobarbital-induced hepatic CYP mRNA expression and CYP-catalyzed reactions in female rats

Sex differences in subacute toxicity and hepatic microsomal metabolism of triptolide in rats

Proteasome-dependent degradation of cytochromes P450 2E1 and 2B1 expressed in tetracycline-regulated HeLa cells

Modification by curcumin of mutagenic activation of carcinogenic N‐nitrosamines by extrahepatic cytochromes P‐450 2B1 and 2E1 in rats

Angiotensin II–Induced Vascular Smooth Muscle Cell Migration and Growth Are Mediated by Cytochrome P450 1B1–Dependent Superoxide Generation

Role for mitogen-activated protein kinases in phenobarbital-induced expression of cytochrome P450 2B in primary cultures of rat hepatocytes

A mechanism-based integrated pharmacokinetic enzyme model describing the time course and magnitude of phenobarbital-mediated enzyme induction in the rat

Effects of short-term in vivo exposure to polybrominated diphenyl ethers on thyroid hormones and hepatic enzyme activities in weanling rats

A technical mixture of 2,2′,4,4′-tetrabromo diphenyl ether (BDE47) and brominated furans triggers aryl hydrocarbon receptor (AhR) mediated gene expression and toxicity

Induction of CYP2B1/2 and nicotine metabolism by ethanol in rat liver but not rat brain

Effect of naturally occurring plant phenolics on the induction of drug metabolizing enzymes by o-toluidine

Cytochrome P450 gene induction in rats ex vivo assessed by quantitative real-time reverse transcriptase-polymerase chain reaction (TaqMan)

Homology modeling and molecular dynamics of CYP1A1 and CYP2B1 to explore the metabolism of aryl derivatives by docking and experimental assays

N-Nitrosodiethylamine genotoxicity in primary rat hepatocytes: Effects of cytochrome P450 induction by phenobarbital

Cytochrome-P450 2B1 gene silencing attenuates puromycin aminonucleoside-induced cytotoxicity in glomerular epithelial cells

Different profiles of hepatic alkoxyresorufin O-dealkylase activities in small rodents

Green tea extract increases cyclophosphamide-induced teratogenesis by modulating the expression of cytochrome P-450 mRNA

Cancer Prevention Mediated by Caffeic Acid Phenethyl Ester Involves Cyp2b1/2 Modulation in Hepatocarcinogenesis

Overexpression of cerebral and hepatic cytochrome P450s alters behavioral activity of rat offspring following prenatal exposure to lindane

Piperine inhibits aflatoxin B1-induced cytotoxicity and genotoxicity in V79 Chinese hamster cells genetically engineered to express rat cytochrome P4502B1

Differential effects of oltipraz on CYP1A and CYP2B in rat lung

Promoting effects of monomethylarsonic acid, dimethylarsinic acid and trimethylarsine oxide on induction of rat liver preneoplastic glutathione S‐transferase placental form positive foci: A possible reactive oxygen species mechanism

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