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Agmatine attenuates chronic unpredictable mild stress-induced anxiety, depression-like behaviours and cognitive impairment by modulating nitrergic signalling pathway

Brain research, 2017-05, Vol.1663, p.66-77

2017

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Chronic agmatine treatment prevents behavioral manifestations of nicotine withdrawal in mice

European journal of pharmacology, 2015-05, Vol.754, p.190-198

2015

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Agmatine ameliorates type 2 diabetes induced-Alzheimer's disease-like alterations in high-fat diet-fed mice via reactivation of blunted insulin signalling

Neuropharmacology, 2017-02, Vol.113 (Pt A), p.467-479

2017

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Agmatine alleviates ethanol withdrawal-associated cognitive impairment and neurochemical imbalance in rats

Neuroscience letters, 2024-05, Vol.832, p.137804-137804, Article 137804

2024

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Agmatine rescues autistic behaviors in the valproic acid-induced animal model of autism

Neuropharmacology, 2017-02, Vol.113 (Pt A), p.71-81

2017

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Long-term (5 years), high daily dosage of dietary agmatine--evidence of safety: a case report

Journal of medicinal food, 2014-11, Vol.17 (11), p.1256

2014

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Neuroprotective action of agmatine in rotenone-induced model of Parkinson’s disease: Role of BDNF/cREB and ERK pathway

Behavioural brain research, 2020-08, Vol.392, p.112692-112692, Article 112692

2020

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Involvement of agmatine in antidepressant-like effect of HMG-CoA reductase inhibitors in mice

European journal of pharmacology, 2021-02, Vol.892, p.173739-173739, Article 173739

2021

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Agmatine reduces alcohol drinking and produces antinociceptive effects in rodent models of alcohol use disorder

Alcohol (Fayetteville, N.Y.), 2023-06, Vol.109, p.23-33

2023

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Safety and neurochemical profiles of acute and sub-chronic oral treatment with agmatine sulfate

Scientific reports, 2019-09, Vol.9 (1), p.12669-13, Article 12669

2019

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Agmatine ameliorates adjuvant induced arthritis and inflammatory cachexia in rats

Biomedicine & pharmacotherapy, 2017-02, Vol.86, p.271-278

2017

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Evidence for oral agmatine sulfate safety – A 95-day high dosage pilot study with rats

Food and chemical toxicology, 2013-12, Vol.62, p.758-762

2013

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Antidepressant like effect of selective serotonin reuptake inhibitors involve modulation of imidazoline receptors by agmatine

Neuropharmacology, 2009-09, Vol.57 (4), p.415-424

2009

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Neuroprotective effect of agmatine (decarboxylated l-arginine) against oxidative stress and neuroinflammation in rotenone model of Parkinson’s disease

Human & experimental toxicology, 2019-02, Vol.38 (2), p.173-184

2019

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A ketogenic diet modifies glutamate, gamma-aminobutyric acid and agmatine levels in the hippocampus of rats: A microdialysis study

Neuroscience letters, 2017-03, Vol.642, p.158-162

2017

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Agmatine attenuates chronic unpredictable mild stress induced behavioral alteration in mice

European journal of pharmacology, 2013-11, Vol.720 (1-3), p.115-120

2013

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Agmatine-grafted bioreducible poly(-lysine) for gene delivery with low cytotoxicity and high efficiency

Journal of materials chemistry. B, Materials for biology and medicine, 2020-03, Vol.8 (12), p.2418-243

2020

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Functional and pharmacological analysis of agmatine administration in different cerebral ischemia animal models

Brain research bulletin, 2019-03, Vol.146, p.201-212

2019

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Agmatine mitigates behavioral abnormalities and neurochemical dysregulation associated with 3-Nitropropionic acid-induced Huntington's disease in rats

Neurotoxicology (Park Forest South), 2024-05, Vol.102, p.12-28

2024

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Agmatine, an endogenous ligand of imidazoline receptor protects against memory impairment and biochemical alterations in streptozotocin-induced diabetic rats

Progress in neuro-psychopharmacology & biological psychiatry, 2012-04, Vol.37 (1), p.96-105

2012

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Agmatine protects against intracerebroventricular streptozotocin-induced water maze memory deficit, hippocampal apoptosis and Akt/GSK3β signaling disruption

European journal of pharmacology, 2014-08, Vol.736, p.107-114

2014

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Safety and Efficacy of Dietary Agmatine Sulfate in Lumbar Disc-associated Radiculopathy. An Open-label, Dose-escalating Study Followed by a Randomized, Double-blind, Placebo-controlled Trial

Pain medicine (Malden, Mass.), 2010-03, Vol.11 (3), p.356-368

2010

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Involvement of nitric oxide in anticompulsive-like effect of agmatine on marble-burying behaviour in mice

European journal of pharmacology, 2016-01, Vol.770, p.165-171

2016

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Agmatine attenuates rhabdomyolysis-induced acute kidney injury in rats in a dose dependent manner

Life sciences (1973), 2018-09, Vol.208, p.79-86

2018

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Altered plasma levels of arginine metabolites in depression

Journal of psychiatric research, 2020-01, Vol.120, p.21-28

2020

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Agmatine attenuates chronic unpredictable mild stress-induced anxiety, depression-like behaviours and cognitive impairment by modulating nitrergic signalling pathway

Chronic agmatine treatment prevents behavioral manifestations of nicotine withdrawal in mice

Agmatine ameliorates type 2 diabetes induced-Alzheimer's disease-like alterations in high-fat diet-fed mice via reactivation of blunted insulin signalling

Agmatine alleviates ethanol withdrawal-associated cognitive impairment and neurochemical imbalance in rats

Agmatine rescues autistic behaviors in the valproic acid-induced animal model of autism

Long-term (5 years), high daily dosage of dietary agmatine--evidence of safety: a case report

Neuroprotective action of agmatine in rotenone-induced model of Parkinson’s disease: Role of BDNF/cREB and ERK pathway

Involvement of agmatine in antidepressant-like effect of HMG-CoA reductase inhibitors in mice

Agmatine reduces alcohol drinking and produces antinociceptive effects in rodent models of alcohol use disorder

Safety and neurochemical profiles of acute and sub-chronic oral treatment with agmatine sulfate

Agmatine ameliorates adjuvant induced arthritis and inflammatory cachexia in rats

Evidence for oral agmatine sulfate safety – A 95-day high dosage pilot study with rats

Antidepressant like effect of selective serotonin reuptake inhibitors involve modulation of imidazoline receptors by agmatine

Neuroprotective effect of agmatine (decarboxylated l-arginine) against oxidative stress and neuroinflammation in rotenone model of Parkinson’s disease

A ketogenic diet modifies glutamate, gamma-aminobutyric acid and agmatine levels in the hippocampus of rats: A microdialysis study

Agmatine attenuates chronic unpredictable mild stress induced behavioral alteration in mice

Agmatine-grafted bioreducible poly(-lysine) for gene delivery with low cytotoxicity and high efficiency

Functional and pharmacological analysis of agmatine administration in different cerebral ischemia animal models

Agmatine mitigates behavioral abnormalities and neurochemical dysregulation associated with 3-Nitropropionic acid-induced Huntington's disease in rats

Agmatine, an endogenous ligand of imidazoline receptor protects against memory impairment and biochemical alterations in streptozotocin-induced diabetic rats

Agmatine protects against intracerebroventricular streptozotocin-induced water maze memory deficit, hippocampal apoptosis and Akt/GSK3β signaling disruption

Safety and Efficacy of Dietary Agmatine Sulfate in Lumbar Disc-associated Radiculopathy. An Open-label, Dose-escalating Study Followed by a Randomized, Double-blind, Placebo-controlled Trial

Involvement of nitric oxide in anticompulsive-like effect of agmatine on marble-burying behaviour in mice

Agmatine attenuates rhabdomyolysis-induced acute kidney injury in rats in a dose dependent manner

Altered plasma levels of arginine metabolites in depression

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