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Pharmacological polyamine catabolism upregulation with methionine salvage pathway inhibition as an effective prostate cancer therapy

Nature communications, 2020-01, Vol.11 (1), p.52-52, Article 52

2020

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Prostate cancer cells differ in testosterone accumulation, dihydrotestosterone conversion, and androgen receptor signaling response to steroid 5α-reductase inhibitors

The Prostate, 2013-09, Vol.73 (13), p.1470-1482

2013

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Phase I and II Study of the Safety, Virologic Effect, and Pharmacokinetics/Pharmacodynamics of Single-Dose 3-O-(3′,3′-Dimethylsuccinyl)Betulinic Acid (Bevirimat) against Human Immunodeficiency Virus Infection

Antimicrobial Agents and Chemotherapy, 2007-10, Vol.51 (10), p.3574-3581

2007

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Serum‐free complete medium, an alternative medium to mimic androgen deprivation in human prostate cancer cell line models

The Prostate, 2018-02, Vol.78 (3), p.213-221

2018

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Sequential use of the androgen synthesis inhibitors ketoconazole and abiraterone acetate in castration-resistant prostate cancer and the predictive value of circulating androgens

Clinical cancer research, 2014-12, Vol.20 (24), p.6269-6276

2014

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Characterization of Prostate Cancer in a Functional Eunuch

Journal of the National Comprehensive Cancer Network, 2016-09, Vol.14 (9), p.1054-1060

2016

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Safety and Pharmacokinetics of Bevirimat (PA-457), a Novel Inhibitor of Human Immunodeficiency Virus Maturation, in Healthy Volunteers

Antimicrobial Agents and Chemotherapy, 2007-09, Vol.51 (9), p.3063-3066

2007

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A phase I study of the anaplastic lymphoma kinase inhibitor ceritinib in combination with gemcitabine‐based chemotherapy in patients with advanced solid tumors

International journal of cancer, 2021-12, Vol.149 (12), p.2063-2074

2021

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A multicentre phase 1b/2 study of tivozanib in patients with advanced inoperable hepatocellular carcinoma

British journal of cancer, 2020-03, Vol.122 (7), p.963-970

2020

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Lack of Bioequivalence of Ciprofloxacin When Administered with Calcium-Fortified Orange Juice: A New Twist on an Old Interaction

Journal of clinical pharmacology, 2002-04, Vol.42 (4), p.461-466

2002

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Multicenter phase 2 trial of nintedanib in advanced nonpancreatic neuroendocrine tumors

Cancer, 2020-08, Vol.126 (16), p.3689-3697

2020

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A Phase Ib Study of the FGFR/VEGFR Inhibitor Dovitinib With Gemcitabine and Capecitabine in Advanced Solid Tumor and Pancreatic Cancer Patients

American journal of clinical oncology, 2019-02, Vol.42 (2), p.184-189

2019

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Roles for the backdoor pathway of androgen metabolism in prostate cancer response to castration and drug treatment

International journal of biological sciences, 2014-01, Vol.10 (6), p.596-601

2014

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Effect of fluconazole on the disposition of phenytoin

Clinical pharmacology and therapeutics, 1991-04, Vol.49 (4), p.420-425

1991

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Pharmacokinetic analysis of the FAK scaffold inhibitor C4 in dogs

European journal of drug metabolism and pharmacokinetics, 2016-02, Vol.41 (1), p.55-67

2016

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Ciprofloxacin concentrations in lung tissue following a single 400 mg intravenous dose

Journal of antimicrobial chemotherapy, 1999-03, Vol.43 Suppl A (suppl_1), p.43-48

1999

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Increased gastric pH and the bioavailability of fluconazole and ketoconazole

Annals of internal medicine, 1991-05, Vol.114 (9), p.755-757

1991

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Assessment of the enzymuria resulting from gentamicin alone and combinations of gentamicin with various beta-lactam antibiotics

The Annals of pharmacotherapy, 1997-06, Vol.31 (6), p.696-703

1997

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Androgenic biomarker prof|ling in human matrices and cell culture samples using high throughput, electrospray tandem mass spectrometry

The Prostate, 2014-05, Vol.74 (7), p.722-731

2014

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Comparative Pharmacokinetics of Oral Ceftibuten, Cefixime, Cefaclor, and Cefuroxime Axetil in Healthy Volunteers

Pharmacotherapy, 1997-01, Vol.17 (1), p.121-125

1997

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Large surface area activated charcoal and the inhibition of aspirin absorption

Annals of emergency medicine, 1989-05, Vol.18 (5), p.547-552

1989

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Pharmacodynamic modeling of the in vivo interaction between cefotaxime and ofloxacin by using serum ultrafiltrate inhibitory titers

Antimicrobial Agents and Chemotherapy, 1997-05, Vol.41 (5), p.1108-1114

1997

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Oxaprozin and Piroxicam, Nonsteroidal Antiinflammatory Drugs with Long Half-Lives: Effect of Protein-Binding Differences on Steady-State Pharmacokinetics

Journal of clinical pharmacology, 1997-04, Vol.37 (4), p.267-278

1997

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Effect of Aging on Atenolol Pharmacokinetics and Pharmacodynamics

Journal of clinical pharmacology, 1995-08, Vol.35 (8), p.807-814

1995

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Combined use of ciprofloxacin and sucralfate

DICP (Cincinnati, Ohio), 1991-06, Vol.25 (6), p.578-582

1991

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Pharmacological polyamine catabolism upregulation with methionine salvage pathway inhibition as an effective prostate cancer therapy

Prostate cancer cells differ in testosterone accumulation, dihydrotestosterone conversion, and androgen receptor signaling response to steroid 5α-reductase inhibitors

Phase I and II Study of the Safety, Virologic Effect, and Pharmacokinetics/Pharmacodynamics of Single-Dose 3-O-(3′,3′-Dimethylsuccinyl)Betulinic Acid (Bevirimat) against Human Immunodeficiency Virus Infection

Serum‐free complete medium, an alternative medium to mimic androgen deprivation in human prostate cancer cell line models

Sequential use of the androgen synthesis inhibitors ketoconazole and abiraterone acetate in castration-resistant prostate cancer and the predictive value of circulating androgens

Characterization of Prostate Cancer in a Functional Eunuch

Safety and Pharmacokinetics of Bevirimat (PA-457), a Novel Inhibitor of Human Immunodeficiency Virus Maturation, in Healthy Volunteers

A phase I study of the anaplastic lymphoma kinase inhibitor ceritinib in combination with gemcitabine‐based chemotherapy in patients with advanced solid tumors

A multicentre phase 1b/2 study of tivozanib in patients with advanced inoperable hepatocellular carcinoma

Lack of Bioequivalence of Ciprofloxacin When Administered with Calcium-Fortified Orange Juice: A New Twist on an Old Interaction

Multicenter phase 2 trial of nintedanib in advanced nonpancreatic neuroendocrine tumors

A Phase Ib Study of the FGFR/VEGFR Inhibitor Dovitinib With Gemcitabine and Capecitabine in Advanced Solid Tumor and Pancreatic Cancer Patients

Roles for the backdoor pathway of androgen metabolism in prostate cancer response to castration and drug treatment

Effect of fluconazole on the disposition of phenytoin

Pharmacokinetic analysis of the FAK scaffold inhibitor C4 in dogs

Ciprofloxacin concentrations in lung tissue following a single 400 mg intravenous dose

Increased gastric pH and the bioavailability of fluconazole and ketoconazole

Assessment of the enzymuria resulting from gentamicin alone and combinations of gentamicin with various beta-lactam antibiotics

Androgenic biomarker prof|ling in human matrices and cell culture samples using high throughput, electrospray tandem mass spectrometry

Comparative Pharmacokinetics of Oral Ceftibuten, Cefixime, Cefaclor, and Cefuroxime Axetil in Healthy Volunteers

Large surface area activated charcoal and the inhibition of aspirin absorption

Pharmacodynamic modeling of the in vivo interaction between cefotaxime and ofloxacin by using serum ultrafiltrate inhibitory titers

Oxaprozin and Piroxicam, Nonsteroidal Antiinflammatory Drugs with Long Half-Lives: Effect of Protein-Binding Differences on Steady-State Pharmacokinetics

Effect of Aging on Atenolol Pharmacokinetics and Pharmacodynamics

Combined use of ciprofloxacin and sucralfate

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