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Benfotiamine and Cognitive Decline in Alzheimer's Disease: Results of a Randomized Placebo-Controlled Phase IIa Clinical Trial

Journal of Alzheimer's disease, 2020-01, Vol.78 (3), p.989-1010

2020

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Mitochondrial abnormalities in Alzheimer brain: Mechanistic implications

Annals of neurology, 2005-05, Vol.57 (5), p.695-703

2005

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Novel Metabolic Abnormalities in the Tricarboxylic Acid Cycle in Peripheral Cells From Huntington's Disease Patients

PloS one, 2016-09, Vol.11 (9), p.e0160384

2016

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Changes in inflammatory processes associated with selective vulnerability following mild impairment of oxidative metabolism

Neurobiology of disease, 2007-05, Vol.26 (2), p.353-362

2007

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Thiamine and Oxidants Interact to Modify Cellular Calcium Stores

Neurochemical research, 2010-12, Vol.35 (12), p.2107-2116

2010

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Alpha‐ketoglutarate dehydrogenase complex‐dependent succinylation of proteins in neurons and neuronal cell lines

Journal of neurochemistry, 2015-07, Vol.134 (1), p.86-96

2015

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Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's disease

Neurochemistry international, 2009-02, Vol.54 (2), p.111-118

2009

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Reversal of Thiamine Deficiency-Induced Neurodegeneration

Journal of neuropathology and experimental neurology, 2003-02, Vol.62 (2), p.195-207

2003

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Mice deficient in dihydrolipoyl succinyl transferase show increased vulnerability to mitochondrial toxins

Neurobiology of disease, 2009-11, Vol.36 (2), p.320-330

2009

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Abnormalities in the Tricarboxylic Acid Cycle in Huntington Disease and in a Huntington Disease Mouse Model

Journal of neuropathology and experimental neurology, 2015-06, Vol.74 (6), p.527-537

2015

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Thiamine deficiency induces oxidative stress and exacerbates the plaque pathology in Alzheimer's mouse model

Neurobiology of aging, 2009-10, Vol.30 (10), p.1587-1600

2009

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The negative impact of α‐ketoglutarate dehydrogenase complex deficiency on matrix substrate‐level phosphorylation

The FASEB journal, 2013-06, Vol.27 (6), p.2392-2406

2013

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Dichloroacetate exerts therapeutic effects in transgenic mouse models of Huntington's disease

Annals of neurology, 2001-07, Vol.50 (1), p.112-116

2001

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Interactions of endoplasmic reticulum and mitochondria Ca(2+) stores with capacitative calcium entry

Metabolic brain disease, 2014-12, Vol.29 (4), p.1083-1093

2014

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Coordination and timing of spine and hip joints during full body reaching tasks

Human movement science, 2007-02, Vol.26 (1), p.124-140

2007

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Cisplatin-Induced Toxicity Is Associated with Platinum Deposition in Mouse Kidney Mitochondria in Vivo and with Selective Inactivation of the α-Ketoglutarate Dehydrogenase Complex in LLC-PK1 Cells

Biochemistry (Easton), 2006-07, Vol.45 (29), p.8959-8971

2006

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Peripheral inflammatory mechanisms modulate microglial activation in response to mild impairment of oxidative metabolism

Neurochemistry international, 2006-10, Vol.49 (5), p.548-556

2006

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Translocation of Amyloid Precursor Protein C-terminal Fragment(s) to the Nucleus Precedes Neuronal Death due to Thiamine Deficiency-induced Mild Impairment of Oxidative Metabolism

Neurochemical research, 2008-07, Vol.33 (7), p.1365-1372

2008

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Transglutaminase Activity Is Present in Highly Purified Nonsynaptosomal Mouse Brain and Liver Mitochondria

Biochemistry (Easton), 2005-05, Vol.44 (21), p.7830-7843

2005

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Oxidative Stress Is Associated with Region-Specific Neuronal Death During Thiamine Deficiency

Journal of neuropathology and experimental neurology, 1999-09, Vol.58 (9), p.946-958

1999

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Mitochondrial function in fibroblasts with aging in culture and/or Alzheimer's disease

Neurobiology of aging, 2005-06, Vol.26 (6), p.839-848

2005

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Correlations of disability and biologic alterations in Alzheimer brain and test of significance by a therapeutic trial in humans

Journal of Alzheimer's disease, 2006-07, Vol.9 (2), p.207-218

2006

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CD40–CD40L interactions promote neuronal death in a model of neurodegeneration due to mild impairment of oxidative metabolism

Neurochemistry international, 2005-08, Vol.47 (3), p.204-215

2005

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Mitochondrial enzymes in schizophrenia

Journal of molecular neuroscience, 2004-01, Vol.24 (2), p.315-322

2004

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Benfotiamine and Cognitive Decline in Alzheimer's Disease: Results of a Randomized Placebo-Controlled Phase IIa Clinical Trial

Mitochondrial abnormalities in Alzheimer brain: Mechanistic implications

Protocol for a seamless phase 2A-phase 2B randomized double-blind placebo-controlled trial to evaluate the safety and efficacy of benfotiamine in patients with early Alzheimer's disease (BenfoTeam)

Novel Metabolic Abnormalities in the Tricarboxylic Acid Cycle in Peripheral Cells From Huntington's Disease Patients

Changes in inflammatory processes associated with selective vulnerability following mild impairment of oxidative metabolism

Thiamine and Oxidants Interact to Modify Cellular Calcium Stores

Alpha‐ketoglutarate dehydrogenase complex‐dependent succinylation of proteins in neurons and neuronal cell lines

Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's disease

Reversal of Thiamine Deficiency-Induced Neurodegeneration

Mice deficient in dihydrolipoyl succinyl transferase show increased vulnerability to mitochondrial toxins

Abnormalities in the Tricarboxylic Acid Cycle in Huntington Disease and in a Huntington Disease Mouse Model

Thiamine deficiency induces oxidative stress and exacerbates the plaque pathology in Alzheimer's mouse model

The negative impact of α‐ketoglutarate dehydrogenase complex deficiency on matrix substrate‐level phosphorylation

Dichloroacetate exerts therapeutic effects in transgenic mouse models of Huntington's disease

Interactions of endoplasmic reticulum and mitochondria Ca(2+) stores with capacitative calcium entry

Coordination and timing of spine and hip joints during full body reaching tasks

Cisplatin-Induced Toxicity Is Associated with Platinum Deposition in Mouse Kidney Mitochondria in Vivo and with Selective Inactivation of the α-Ketoglutarate Dehydrogenase Complex in LLC-PK1 Cells

Peripheral inflammatory mechanisms modulate microglial activation in response to mild impairment of oxidative metabolism

Translocation of Amyloid Precursor Protein C-terminal Fragment(s) to the Nucleus Precedes Neuronal Death due to Thiamine Deficiency-induced Mild Impairment of Oxidative Metabolism

Transglutaminase Activity Is Present in Highly Purified Nonsynaptosomal Mouse Brain and Liver Mitochondria

Oxidative Stress Is Associated with Region-Specific Neuronal Death During Thiamine Deficiency

Mitochondrial function in fibroblasts with aging in culture and/or Alzheimer's disease

Correlations of disability and biologic alterations in Alzheimer brain and test of significance by a therapeutic trial in humans

CD40–CD40L interactions promote neuronal death in a model of neurodegeneration due to mild impairment of oxidative metabolism

Mitochondrial enzymes in schizophrenia

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