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Safety, efficacy, and dose response of the maturation inhibitor GSK3532795 (formerly known as BMS-955176) plus tenofovir/emtricitabine once daily in treatment-naive HIV-1-infected adults: Week 24 primary analysis from a randomized Phase IIb trial

PloS one, 2018-10, Vol.13 (10), p.e0205368-e0205368

2018

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Antiviral Activity, Safety, and Exposure–Response Relationships of GSK3532795, a Second-Generation Human Immunodeficiency Virus Type 1 Maturation Inhibitor, Administered as Monotherapy or in Combination With Atazanavir With or Without Ritonavir in a Phase 2a Randomized, Dose-Ranging, Controlled Trial (AI468002)

Clinical infectious diseases, 2017-08, Vol.65 (3), p.442-452

2017

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Design, Synthesis, and SAR of C-3 Benzoic Acid, C-17 Triterpenoid Derivatives. Identification of the HIV-1 Maturation Inhibitor 4-((1 R,3a S,5a R,5b R,7a R,11a S,11b R,13a R,13b R)-3a-((2-(1,1-Dioxidothiomorpholino)ethyl)amino)-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)-2,3,3a,4,5,5a,5b,6,7,7a,8,11,11a,11b,12,13,13a,13b-octadecahydro-1 H-cyclopenta[ a]chrysen-9-yl)benzoic Acid (GSK3532795, BMS-955176)

Journal of medicinal chemistry, 2018-08, Vol.61 (16), p.7289-7313

2018

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Both the high affinity thrombin receptor (GPIb-IX-V) and GPIIb/IIIa are implicated in expression of thrombin-induced platelet procoagulant activity

Thrombosis and haemostasis, 2001, Vol.86 (4), p.1065

2001

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Cause-specific mortality for 240 causes in China during 1990–2013: a systematic subnational analysis for the Global Burden of Disease Study 2013

The Lancet (British edition), 2016-01, Vol.387 (10015), p.251-272

2016

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Glycoprotein IIb/IIIa Receptor Antagonists Inhibit the Development of Platelet Procoagulant Activity

Thrombosis research, 1998-06, Vol.90 (6), p.247-258

1998

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Mathematical Model of Serine Protease Inhibition in the Tissue Factor Pathway to Thrombin (∗)

The Journal of biological chemistry, 1995-10, Vol.270 (43), p.25383-25387

1995

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Changes in health in England, with analysis by English regions and areas of deprivation, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013

The Lancet (British edition), 2015-12, Vol.386 (10010), p.2257-2274

2015

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The public cost of motorcycle trauma

JAMA : the journal of the American Medical Association, 1988-07, Vol.260 (2), p.221

1988

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Evaluation of potentially preventable deaths among pedestrian and bicyclist fatalities

JAMA : the journal of the American Medical Association, 1989-01, Vol.261 (4), p.566

1989

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Young Man with Sore Throat, Headache, and Rash

The Journal of emergency medicine, 2016-02, Vol.50 (2), p.e99-e101

2016

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Physician Consent and Researchers' Access to Patients

Epidemiology (Cambridge, Mass.), 1990-03, Vol.1 (2), p.160-163

1990

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Appointment-keeping compliance. Unexpected benefits from an unorthodox program

The Journal of the Kansas Medical Society, 1983-09, Vol.84 (9), p.470

Dicker, R B

1983

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RNA biomarkers associated with metastatic progression in prostate cancer: a multi-institutional high-throughput analysis of SChLAP1

The lancet oncology, 2014-12, Vol.15 (13), p.1469-1480

2014

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Quantifying Unnecessary Normal Tissue Complication Risks due to Suboptimal Planning: A Secondary Study of RTOG 0126

International journal of radiation oncology, biology, physics, 2015-06, Vol.92 (2), p.228-235

2015

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A hormone-DNA repair circuit governs the response to genotoxic insult

Cancer discovery, 2013-11, Vol.3 (11), p.1254-1271

2013

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What is the ideal radiotherapy dose to treat prostate cancer? A meta-analysis of biologically equivalent dose escalation

Radiotherapy and oncology, 2015-06, Vol.115 (3), p.295-300

2015

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A Patent Ductus Arteriosus Severity Score Predicts Chronic Lung Disease or Death before Discharge

The Journal of pediatrics, 2015-12, Vol.167 (6), p.1354-1361.e2

2015

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RB Loss Promotes Prostate Cancer Metastasis

Cancer research (Chicago, Ill.), 2017-02, Vol.77 (4), p.982-995

2017

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Novel actions of next-generation taxanes benefit advanced stages of prostate cancer

Clinical cancer research, 2015-02, Vol.21 (4), p.795-807

2015

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Genomic Prostate Cancer Classifier Predicts Biochemical Failure and Metastases in Patients After Postoperative Radiation Therapy

International journal of radiation oncology, biology, physics, 2014-08, Vol.89 (5), p.1038-1046

2014

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Genomic classifier identifies men with adverse pathology after radical prostatectomy who benefit from adjuvant radiation therapy

Journal of clinical oncology, 2015-03, Vol.33 (8), p.944-951

2015

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Individual Patient-Level Meta-Analysis of the Performance of the Decipher Genomic Classifier in High-Risk Men After Prostatectomy to Predict Development of Metastatic Disease

Journal of clinical oncology, 2017-06, Vol.35 (18), p.1991-1998

2017

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Do the changes in muscle mass, muscle direction, and rotations of the condyles that occur after sagittal split advancement osteotomies play a role in the aetiology of progressive condylar resorption?

International journal of oral and maxillofacial surgery, 2015-05, Vol.44 (5), p.627-631

2015

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Safety, efficacy, and dose response of the maturation inhibitor GSK3532795 (formerly known as BMS-955176) plus tenofovir/emtricitabine once daily in treatment-naive HIV-1-infected adults: Week 24 primary analysis from a randomized Phase IIb trial

Both the high affinity thrombin receptor (GPIb-IX-V) and GPIIb/IIIa are implicated in expression of thrombin-induced platelet procoagulant activity

Cause-specific mortality for 240 causes in China during 1990–2013: a systematic subnational analysis for the Global Burden of Disease Study 2013

Glycoprotein IIb/IIIa Receptor Antagonists Inhibit the Development of Platelet Procoagulant Activity

Mathematical Model of Serine Protease Inhibition in the Tissue Factor Pathway to Thrombin (∗)

Changes in health in England, with analysis by English regions and areas of deprivation, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013

The public cost of motorcycle trauma

Evaluation of potentially preventable deaths among pedestrian and bicyclist fatalities

Young Man with Sore Throat, Headache, and Rash

Physician Consent and Researchers' Access to Patients

Appointment-keeping compliance. Unexpected benefits from an unorthodox program

RNA biomarkers associated with metastatic progression in prostate cancer: a multi-institutional high-throughput analysis of SChLAP1

Quantifying Unnecessary Normal Tissue Complication Risks due to Suboptimal Planning: A Secondary Study of RTOG 0126

A hormone-DNA repair circuit governs the response to genotoxic insult

Development and validation of a 24-gene predictor of response to postoperative radiotherapy in prostate cancer: a matched, retrospective analysis

What is the ideal radiotherapy dose to treat prostate cancer? A meta-analysis of biologically equivalent dose escalation

A Patent Ductus Arteriosus Severity Score Predicts Chronic Lung Disease or Death before Discharge

RB Loss Promotes Prostate Cancer Metastasis

Novel actions of next-generation taxanes benefit advanced stages of prostate cancer

Genomic Prostate Cancer Classifier Predicts Biochemical Failure and Metastases in Patients After Postoperative Radiation Therapy

Genomic classifier identifies men with adverse pathology after radical prostatectomy who benefit from adjuvant radiation therapy

Individual Patient-Level Meta-Analysis of the Performance of the Decipher Genomic Classifier in High-Risk Men After Prostatectomy to Predict Development of Metastatic Disease

Do the changes in muscle mass, muscle direction, and rotations of the condyles that occur after sagittal split advancement osteotomies play a role in the aetiology of progressive condylar resorption?

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