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Sphingosine-1-phosphate: From insipid lipid to a key regulator

The Journal of biological chemistry, 2020-03, Vol.295 (10), p.3371-3384

Spiegel, Sarah

2020

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The outs and the ins of sphingosine-1-phosphate in immunity

Nature reviews. Immunology, 2011-06, Vol.11 (6), p.403

2011

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Export of sphingosine-1-phosphate and cancer progression

Journal of lipid research, 2014-09, Vol.55 (9), p.1839-1846

2014

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Targeting the sphingosine-1-phosphate axis in cancer, inflammation and beyond

Nature reviews. Drug discovery, 2013-09, Vol.12 (9), p.688

2013

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Sphingosine kinase and sphingosine-1-phosphate in liver pathobiology

Critical reviews in biochemistry and molecular biology, 2017-09, Vol.52 (5), p.543-553

2017

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New insights into functions of the sphingosine-1-phosphate transporter SPNS2

Journal of lipid research, 2019-03, Vol.60 (3), p.484-489

2019

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Sphingosine 1-phosphate and ceramide 1-phosphate: expanding roles in cell signaling

Journal of cell science, 2005-10, Vol.118 (20), p.4605-4612

2005

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Sphingolipid metabolites in inflammatory disease

Nature (London), 2014-06, Vol.510 (7503), p.58-67

2014

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Regulation of Histone Acetylation in the Nucleus by Sphingosine-1-Phosphate

Science (American Association for the Advancement of Science), 2009-09, Vol.325 (5945), p.1254-1257

2009

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Sphingosine-1-Phosphate Links Persistent STAT3 Activation, Chronic Intestinal Inflammation, and Development of Colitis-Associated Cancer

Cancer cell, 2013-01, Vol.23 (1), p.107-120

2013

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A specific sphingosine kinase 1 inhibitor attenuates airway hyperresponsiveness and inflammation in a mast cell–dependent murine model of allergic asthma

Journal of allergy and clinical immunology, 2013-02, Vol.131 (2), p.501-511.e1

2013

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Autocrine and paracrine roles of sphingosine-1-phosphate

Trends in endocrinology and metabolism, 2007-10, Vol.18 (8), p.300-307

2007

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Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2

Nature (London), 2010-06, Vol.465 (7301), p.1084-1088

2010

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Sphingosine-1-Phosphate Produced by Sphingosine Kinase 1 Promotes Breast Cancer Progression by Stimulating Angiogenesis and Lymphangiogenesis

Cancer research (Chicago, Ill.), 2012-02, Vol.72 (3), p.726-735

2012

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Sphingosine kinase 1/S1P receptor signaling axis is essential for cellular uptake of Neisseria meningitidis in brain endothelial cells

PLoS pathogens, 2023-11, Vol.19 (11), p.e1011842-e1011842

2023

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FTY720/fingolimod decreases hepatic steatosis and expression of fatty acid synthase in diet-induced nonalcoholic fatty liver disease in mice

Journal of lipid research, 2019-07, Vol.60 (7), p.1311-1322

2019

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Sphingosine-1-phosphate: the Swiss army knife of sphingolipid signaling

Journal of lipid research, 2009-04, Vol.50 (Suppl), p.S272-S276

2009

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Essential Role for Sphingosine Kinases in Neural and Vascular Development

Molecular and Cellular Biology, 2005-12, Vol.25 (24), p.11113-11121

2005

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Export and functions of sphingosine-1-phosphate

Biochimica et biophysica acta, 2009-07, Vol.1791 (7), p.692-696

2009

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Sphingosine-1-phosphate and estrogen signaling in breast cancer

Advances in biological regulation, 2016-01, Vol.60, p.160-165

2016

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Estradiol Induces Export of Sphingosine 1-Phosphate from Breast Cancer Cells via ABCC1 and ABCG2

The Journal of biological chemistry, 2010-04, Vol.285 (14), p.10477-10486

2010

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Apoptosis induces expression of sphingosine kinase 1 to release sphingosine‐1‐phosphate as a “come‐and‐get‐me” signal

The FASEB journal, 2008-08, Vol.22 (8), p.2629-2638

2008

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Autophagy Induced by Deficiency of Sphingosine-1-phosphate Phosphohydrolase 1 Is Switched to Apoptosis by Calpain-mediated Autophagy-related Gene 5 (Atg5) Cleavage

The Journal of biological chemistry, 2011-12, Vol.286 (52), p.44380-44390

2011

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Targeting sphingosine-1-phosphate: A novel avenue for cancer therapeutics

Cancer cell, 2006-03, Vol.9 (3), p.148-150

2006

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Cross-talk between LPA1 and epidermal growth factor receptors mediates up-regulation of sphingosine kinase 1 to promote gastric cancer cell motility and invasion

Cancer research (Chicago, Ill.), 2008-08, Vol.68 (16), p.6569-6577

2008

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Sphingosine-1-phosphate: From insipid lipid to a key regulator

The outs and the ins of sphingosine-1-phosphate in immunity

Export of sphingosine-1-phosphate and cancer progression

Targeting the sphingosine-1-phosphate axis in cancer, inflammation and beyond

Sphingosine kinase and sphingosine-1-phosphate in liver pathobiology

New insights into functions of the sphingosine-1-phosphate transporter SPNS2

Sphingosine 1-phosphate and ceramide 1-phosphate: expanding roles in cell signaling

Sphingolipid metabolites in inflammatory disease

Regulation of Histone Acetylation in the Nucleus by Sphingosine-1-Phosphate

Sphingosine-1-Phosphate Links Persistent STAT3 Activation, Chronic Intestinal Inflammation, and Development of Colitis-Associated Cancer

A specific sphingosine kinase 1 inhibitor attenuates airway hyperresponsiveness and inflammation in a mast cell–dependent murine model of allergic asthma

Autocrine and paracrine roles of sphingosine-1-phosphate

Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2

Sphingosine-1-Phosphate Produced by Sphingosine Kinase 1 Promotes Breast Cancer Progression by Stimulating Angiogenesis and Lymphangiogenesis

Sphingosine kinase 1/S1P receptor signaling axis is essential for cellular uptake of Neisseria meningitidis in brain endothelial cells

FTY720/fingolimod decreases hepatic steatosis and expression of fatty acid synthase in diet-induced nonalcoholic fatty liver disease in mice

Sphingosine-1-phosphate: the Swiss army knife of sphingolipid signaling

Essential Role for Sphingosine Kinases in Neural and Vascular Development

Export and functions of sphingosine-1-phosphate

Sphingosine-1-phosphate and estrogen signaling in breast cancer

Estradiol Induces Export of Sphingosine 1-Phosphate from Breast Cancer Cells via ABCC1 and ABCG2

Apoptosis induces expression of sphingosine kinase 1 to release sphingosine‐1‐phosphate as a “come‐and‐get‐me” signal

Autophagy Induced by Deficiency of Sphingosine-1-phosphate Phosphohydrolase 1 Is Switched to Apoptosis by Calpain-mediated Autophagy-related Gene 5 (Atg5) Cleavage

Targeting sphingosine-1-phosphate: A novel avenue for cancer therapeutics

Cross-talk between LPA1 and epidermal growth factor receptors mediates up-regulation of sphingosine kinase 1 to promote gastric cancer cell motility and invasion

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