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Advancing research and development of anti-infectives for children with a focus on antiretroviral therapy: A clinical development perspective

International journal of antimicrobial agents, 2024-10, Vol.64 (4), p.107306, Article 107306

2024

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A Model-Based Approach Supporting Abacavir/Dolutegravir/Lamivudine Fixed-Dose Combination Approval in Children Living with HIV-1

Journal of clinical pharmacology, 2024-09

2024

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Acute lung injury and other serious complications of Plasmodium vivax malaria

The Lancet infectious diseases, 2008-07, Vol.8 (7), p.449-454

2008

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Effect of raxibacumab on immunogenicity of Anthrax Vaccine Adsorbed: a phase 4, open-label, parallel-group, randomised non-inferiority study

The Lancet infectious diseases, 2020-08, Vol.20 (8), p.983-991

2020

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Monocyte Trajectories Endotypes Are Associated With Worsening in Septic Patients

Frontiers in immunology, 2021-11, Vol.12, p.795052-795052

2021

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Current views of haemolytic streptococcal pathogenesis

Current opinion in infectious diseases, 2014-04, Vol.27 (2), p.155-164

2014

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A pharmacometrics approach to assess the feasibility of capillary microsampling to replace venous sampling in clinical studies: Tafenoquine case study

British journal of clinical pharmacology, 2023-03, Vol.89 (3), p.1187-1197

2023

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Bromine, bear-claw scratch fasciotomies, and the Eagle effect: management of group A streptococcal necrotising fasciitis and its association with trauma

The Lancet infectious diseases, 2015, Vol.15 (1), p.109-121

2015

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Herpes DNAemia and TTV Viraemia in Intensive Care Unit Critically Ill Patients: A Single-Centre Prospective Longitudinal Study

Frontiers in immunology, 2021-11, Vol.12, p.698808-698808

2021

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Vaccine-induced, but not natural immunity, against the Streptococcal inhibitor of complement protects against invasive disease

npj vaccines, 2021-04, Vol.6 (1), p.62-62, Article 62

2021

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Optimal balance of benefit versus risk for tafenoquine in the treatment of Plasmodium vivax malaria

Malaria journal, 2024-05, Vol.23 (1), p.145-145, Article 145

2024

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Comment on 'The clinical pharmacology of tafenoquine in the radical cure of Plasmodium vivax malaria: An individual patient data meta-analysis'

eLife, 2024-02, Vol.13

2024

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Characterization of Neisseria meningitidis Isolates That Do Not Express the Virulence Factor and Vaccine Antigen Factor H Binding Protein

Clinical and Vaccine Immunology, 2011-06, Vol.18 (6), p.1002-1014

2011

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Concomitant Assessment of Monocyte HLA-DR Expression and Ex Vivo TNF-α Release as Markers of Adverse Outcome after Various Injuries-Insights from the REALISM Study

Journal of clinical medicine, 2022-01, Vol.11 (1), p.96

2022

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Tafenoquine exposure assessment, safety, and relapse prevention efficacy in children with Plasmodium vivax malaria: open-label, single-arm, non-comparative, multicentre, pharmacokinetic bridging, phase 2 trial

The lancet child & adolescent health, 2022-02, Vol.6 (2), p.86-95

2022

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Distinct binding and immunogenic properties of the gonococcal homologue of meningococcal factor h binding protein

PLoS pathogens, 2013-08, Vol.9 (8), p.e1003528

2013

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Design and evaluation of meningococcal vaccines through structure-based modification of host and pathogen molecules

PLoS pathogens, 2012-10, Vol.8 (10), p.e1002981

2012

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Hospital-based study of viridans streptococcal bacteraemia in children and adults

The Journal of infection, 2008-02, Vol.56 (2), p.103-107

2008

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First Human Use of a New Robotic-Assisted Fiber Optic Sensing Navigation System for Small Peripheral Pulmonary Nodules

Respiration, 2019-08, Vol.98 (2), p.142-150

2019

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Immunity to uropathogens: the emerging roles of inflammasomes

Nature reviews. Urology, 2017-05, Vol.14 (5), p.284-295

2017

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Plasmodium vivax in Children: Hidden Burden and Conspicuous Challenges, a Narrative Review

Infectious diseases and therapy, 2023-01, Vol.12 (1), p.33-51

2023

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The impact of twice-daily consultant ward rounds on the length of stay in two general medical wards – effect on training?

Clinical medicine (London, England), 2012-04, Vol.12 (2), p.186-187

2012

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The REAnimation Low Immune Status Markers (REALISM) project: a protocol for broad characterisation and follow-up of injury-induced immunosuppression in intensive care unit (ICU) critically ill patients

BMJ open, 2017-06, Vol.7 (6), p.e015734-e015734

2017

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Early herpes and TTV DNAemia in septic shock patients: a pilot study

Intensive care medicine experimental, 2019-05, Vol.7 (1), p.28-13, Article 28

2019

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Advancing research and development of anti-infectives for children with a focus on antiretroviral therapy: A clinical development perspective

A Model-Based Approach Supporting Abacavir/Dolutegravir/Lamivudine Fixed-Dose Combination Approval in Children Living with HIV-1

Acute lung injury and other serious complications of Plasmodium vivax malaria

Effect of raxibacumab on immunogenicity of Anthrax Vaccine Adsorbed: a phase 4, open-label, parallel-group, randomised non-inferiority study

Monocyte Trajectories Endotypes Are Associated With Worsening in Septic Patients

Current views of haemolytic streptococcal pathogenesis

A pharmacometrics approach to assess the feasibility of capillary microsampling to replace venous sampling in clinical studies: Tafenoquine case study

Bromine, bear-claw scratch fasciotomies, and the Eagle effect: management of group A streptococcal necrotising fasciitis and its association with trauma

Herpes DNAemia and TTV Viraemia in Intensive Care Unit Critically Ill Patients: A Single-Centre Prospective Longitudinal Study

Tafenoquine co-administered with dihydroartemisinin–piperaquine for the radical cure of Plasmodium vivax malaria (INSPECTOR): a randomised, placebo-controlled, efficacy and safety study

Vaccine-induced, but not natural immunity, against the Streptococcal inhibitor of complement protects against invasive disease

Optimal balance of benefit versus risk for tafenoquine in the treatment of Plasmodium vivax malaria

Comment on 'The clinical pharmacology of tafenoquine in the radical cure of Plasmodium vivax malaria: An individual patient data meta-analysis'

Characterization of Neisseria meningitidis Isolates That Do Not Express the Virulence Factor and Vaccine Antigen Factor H Binding Protein

Concomitant Assessment of Monocyte HLA-DR Expression and Ex Vivo TNF-α Release as Markers of Adverse Outcome after Various Injuries-Insights from the REALISM Study

Tafenoquine exposure assessment, safety, and relapse prevention efficacy in children with Plasmodium vivax malaria: open-label, single-arm, non-comparative, multicentre, pharmacokinetic bridging, phase 2 trial

Distinct binding and immunogenic properties of the gonococcal homologue of meningococcal factor h binding protein

Design and evaluation of meningococcal vaccines through structure-based modification of host and pathogen molecules

Hospital-based study of viridans streptococcal bacteraemia in children and adults

First Human Use of a New Robotic-Assisted Fiber Optic Sensing Navigation System for Small Peripheral Pulmonary Nodules

Immunity to uropathogens: the emerging roles of inflammasomes

Plasmodium vivax in Children: Hidden Burden and Conspicuous Challenges, a Narrative Review

The impact of twice-daily consultant ward rounds on the length of stay in two general medical wards – effect on training?

The REAnimation Low Immune Status Markers (REALISM) project: a protocol for broad characterisation and follow-up of injury-induced immunosuppression in intensive care unit (ICU) critically ill patients

Early herpes and TTV DNAemia in septic shock patients: a pilot study

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