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PDLIM2: Signaling pathways and functions in cancer suppression and host immunity

Biochimica et biophysica acta. Reviews on cancer, 2021-12, Vol.1876 (2), p.188630-188630, Article 188630

2021

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Epigenetic modulation of antitumor immunity for improved cancer immunotherapy

Molecular cancer, 2021-12, Vol.20 (1), p.171-171, Article 171

2021

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PDLIM2 is a novel E5 ubiquitin ligase enhancer that stabilizes ROC1 and recruits the ROC1-SCF ubiquitin ligase to ubiquitinate and degrade NF-κB RelA

Cell & bioscience, 2024-07, Vol.14 (1), p.99-6, Article 99

2024

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NF-κB RelA is a cell-intrinsic metabolic checkpoint restricting glycolysis

Cell & bioscience, 2024-01, Vol.14 (1), p.11-11, Article 11

2024

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Interleukin-6 Prevents the Initiation but Enhances the Progression of Lung Cancer

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (16), p.3209-3215

2015

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Murine Bronchoalveolar Lavage

Bio-protocol, 2017-05, Vol.7 (10)

2017

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Dual but not single PD-1 or TIM-3 blockade enhances oncolytic virotherapy in refractory lung cancer

Journal for immunotherapy of cancer, 2020-05, Vol.8 (1), p.e000294

2020

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Human T-cell lymphotropic virus: a model of NF-κB-associated tumorigenesis

Viruses, 2011-06, Vol.3 (6), p.714-749

2011

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NF-κB RelA renders tumor-associated macrophages resistant to and capable of directly suppressing CD8+ T cells for tumor promotion

Oncoimmunology, 2018-06, Vol.7 (6), p.e1435250-e1435250

2018

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The tumor suppressor gene WWOX links the canonical and noncanonical NF-κB pathways in HTLV-I Tax-mediated tumorigenesis

Blood, 2011-02, Vol.117 (5), p.1652-1661

2011

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PDLIM2 suppresses human T-cell leukemia virus type I Tax-mediated tumorigenesis by targeting Tax into the nuclear matrix for proteasomal degradation

Blood, 2009-04, Vol.113 (18), p.4370-4380

2009

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PDLIM2 repression by ROS in alveolar macrophages promotes lung tumorigenesis

JCI insight, 2021-03, Vol.6 (5)

2021

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DNA Methylation-Dependent Repression of PDZ-LIM Domain-Containing Protein 2 in Colon Cancer and Its Role as a Potential Therapeutic Target

Cancer research (Chicago, Ill.), 2010-03, Vol.70 (5), p.1766-1772

2010

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Isolation of Murine Alveolar Type II Epithelial Cells

Bio-protocol, 2017-05, Vol.7 (10)

2017

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Human T-Cell Leukemia Virus Type I-Mediated Repression of PDZ-LIM Domain-Containing Protein 2 Involves DNA Methylation But Independent of the Viral Oncoprotein Tax

Neoplasia (New York, N.Y.), 2009-10, Vol.11 (10), p.1036-1041

2009

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Lithium promotes neural precursor cell proliferation: evidence for the involvement of the non-canonical GSK-3β-NF-AT signaling

Cell & bioscience, 2011-05, Vol.1 (1), p.18-18

2011

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Oncovirus Kaposi Sarcoma Herpesvirus (KSHV) Represses Tumor Suppressor PDLIM2 to Persistently Activate Nuclear Factor κB (NF-κB) and STAT3 Transcription Factors for Tumorigenesis and Tumor Maintenance

The Journal of biological chemistry, 2015-03, Vol.290 (12), p.7362-7368

2015

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PDLIM2 restricts Th1 and Th17 differentiation and prevents autoimmune disease

Cell & bioscience, 2012-06, Vol.2 (1), p.23-23, Article 23

2012

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Systematic detection of noncanonical NF-κB activation

Methods in molecular biology (Clifton, N.J.), 2015, Vol.1280, p.121

2015

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Kaposi's sarcoma herpesvirus (KSHV) microRNA K12-1 functions as an oncogene by activating NF-κB/IL-6/STAT3 signaling

Oncotarget, 2016-05, Vol.7 (22), p.33363-33373

2016

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Alveolar Macrophages Inherently Express Programmed Death-1 Ligand 1 for Optimal Protective Immunity and Tolerance

The Journal of immunology (1950), 2021-07, Vol.207 (1), p.110-114

2021

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Differential roles of STAT3 in the initiation and growth of lung cancer

Oncogene, 2015-07, Vol.34 (29), p.3804-3814

2015

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Hsp90 regulates processing of NF-κB2 p100 involving protection of NF-κB-inducing kinase (NIK) from autophagy-mediated degradation

Cell research, 2007-06, Vol.17 (6), p.520-530

2007

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Myeloid STAT3 Promotes Lung Tumorigenesis by Transforming Tumor Immunosurveillance into Tumor-Promoting Inflammation

Cancer immunology research, 2017-03, Vol.5 (3), p.257-268

2017

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Epigenetic Repression of PDZ-LIM Domain-containing Protein 2: IMPLICATIONS FOR THE BIOLOGY AND TREATMENT OF BREAST CANCER

The Journal of biological chemistry, 2010-04, Vol.285 (16), p.11786-11792

2010

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PDLIM2: Signaling pathways and functions in cancer suppression and host immunity

Epigenetic modulation of antitumor immunity for improved cancer immunotherapy

PDLIM2 is a novel E5 ubiquitin ligase enhancer that stabilizes ROC1 and recruits the ROC1-SCF ubiquitin ligase to ubiquitinate and degrade NF-κB RelA

NF-κB RelA is a cell-intrinsic metabolic checkpoint restricting glycolysis

Interleukin-6 Prevents the Initiation but Enhances the Progression of Lung Cancer

Murine Bronchoalveolar Lavage

Dual but not single PD-1 or TIM-3 blockade enhances oncolytic virotherapy in refractory lung cancer

Human T-cell lymphotropic virus: a model of NF-κB-associated tumorigenesis

NF-κB RelA renders tumor-associated macrophages resistant to and capable of directly suppressing CD8+ T cells for tumor promotion

The tumor suppressor gene WWOX links the canonical and noncanonical NF-κB pathways in HTLV-I Tax-mediated tumorigenesis

PDLIM2 suppresses human T-cell leukemia virus type I Tax-mediated tumorigenesis by targeting Tax into the nuclear matrix for proteasomal degradation

PDLIM2 repression by ROS in alveolar macrophages promotes lung tumorigenesis

DNA Methylation-Dependent Repression of PDZ-LIM Domain-Containing Protein 2 in Colon Cancer and Its Role as a Potential Therapeutic Target

Isolation of Murine Alveolar Type II Epithelial Cells

Human T-Cell Leukemia Virus Type I-Mediated Repression of PDZ-LIM Domain-Containing Protein 2 Involves DNA Methylation But Independent of the Viral Oncoprotein Tax

Lithium promotes neural precursor cell proliferation: evidence for the involvement of the non-canonical GSK-3β-NF-AT signaling

Oncovirus Kaposi Sarcoma Herpesvirus (KSHV) Represses Tumor Suppressor PDLIM2 to Persistently Activate Nuclear Factor κB (NF-κB) and STAT3 Transcription Factors for Tumorigenesis and Tumor Maintenance

PDLIM2 restricts Th1 and Th17 differentiation and prevents autoimmune disease

Systematic detection of noncanonical NF-κB activation

Kaposi's sarcoma herpesvirus (KSHV) microRNA K12-1 functions as an oncogene by activating NF-κB/IL-6/STAT3 signaling

Alveolar Macrophages Inherently Express Programmed Death-1 Ligand 1 for Optimal Protective Immunity and Tolerance

Differential roles of STAT3 in the initiation and growth of lung cancer

Hsp90 regulates processing of NF-κB2 p100 involving protection of NF-κB-inducing kinase (NIK) from autophagy-mediated degradation

Myeloid STAT3 Promotes Lung Tumorigenesis by Transforming Tumor Immunosurveillance into Tumor-Promoting Inflammation

Epigenetic Repression of PDZ-LIM Domain-containing Protein 2: IMPLICATIONS FOR THE BIOLOGY AND TREATMENT OF BREAST CANCER

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