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Chlorogenic Acid Prevents UVA-Induced Skin Photoaging through Regulating Collagen Metabolism and Apoptosis in Human Dermal Fibroblasts

International journal of molecular sciences, 2022-06, Vol.23 (13), p.6941

2022

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Secreted HSP90α-LRP1 Signaling Promotes Tumor Metastasis and Chemoresistance in Pancreatic Cancer

International journal of molecular sciences, 2022-05, Vol.23 (10), p.5532

2022

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Exploration of the Fluorescent Properties and the Modulated Activities against Sirtuin Fluorogenic Assays of Chromenone-Derived Natural Products

Molecules (Basel, Switzerland), 2018-05, Vol.23 (5), p.1063

2018

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The Characteristics of Hepatic Gsα-cAMP Axis in HSHF Diet-Fed Obese Insulin Resistance Rats and Genetic Diabetic Mice

Biological and Pharmaceutical Bulletin, 2017/06/01, Vol.40(6), pp.774-781

2017

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The PI3K Inhibitor XH30 Enhances Response to Temozolomide in Drug-Resistant Glioblastoma via the Noncanonical Hedgehog Signaling Pathway

Frontiers in pharmacology, 2021-11, Vol.12, p.749242-749242

2021

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ACAT1 deficiency in myeloid cells promotes glioblastoma progression by enhancing the accumulation of myeloid-derived suppressor cells

Acta pharmaceutica Sinica. B, 2023-12, Vol.13 (12), p.4733-4747

2023

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S-72, a Novel Orally Available Tubulin Inhibitor, Overcomes Paclitaxel Resistance via Inactivation of the STING Pathway in Breast Cancer

Pharmaceuticals (Basel, Switzerland), 2023-05, Vol.16 (5), p.749

2023

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YPD-30, a prodrug of YPD-29B, is an oral small-molecule inhibitor targeting PD-L1 for the treatment of human cancer

Acta pharmaceutica Sinica. B, 2022-06, Vol.12 (6), p.2845-2858

2022

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S1PR1 serves as a viable drug target against pulmonary fibrosis by increasing the integrity of the endothelial barrier of the lung

Acta pharmaceutica Sinica. B, 2023-03, Vol.13 (3), p.1110-1127

2023

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Sphingosine-1-Phosphate Receptor Subtype 1 (S1P1) Modulator IMMH001 Regulates Adjuvant- and Collagen-Induced Arthritis

Frontiers in pharmacology, 2019-09, Vol.10, p.1085-1085

2019

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Antiproliferative effect of HSP90 inhibitor Y306zh against pancreatic cancer is mediated by interruption of AKT and MAPK signaling pathways

Current cancer drug targets, 2014-01, Vol.14 (7), p.671-683

2014

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Honokiol prevents lung metastasis of triple-negative breast cancer by regulating polarization and recruitment of macrophages

European journal of pharmacology, 2023-11, Vol.959, p.176076-176076, Article 176076

2023

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Re-expression of epigenetically silenced PTPRR by histone acetylation sensitizes RAS-mutant lung adenocarcinoma to SHP2 inhibition

Cellular and molecular life sciences : CMLS, 2024-12, Vol.81 (1), p.64-64, Article 64

2024

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Design, Synthesis, and Biological Evaluation of 4‑Methyl Quinazoline Derivatives as Anticancer Agents Simultaneously Targeting Phosphoinositide 3‑Kinases and Histone Deacetylases

Journal of medicinal chemistry, 2019-08, Vol.62 (15), p.6992-7014

2019

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Discovery of Natural Ah Receptor Antagonists from Salvia miltiorrhiza Bunge and Synthesis of Analogs for Tumor Immunotherapy

Journal of medicinal chemistry, 2024-01, Vol.67 (2), p.1243-1261

2024

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Chaperone-mediated autophagy degradation of IGF-1Rβ induced by NVP-AUY922 in pancreatic cancer

Cellular and molecular life sciences : CMLS, 2019-09, Vol.76 (17), p.3433-3447

2019

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Bt354 as a new STAT3 signaling pathway inhibitor against triple negative breast cancer

Journal of drug targeting, 2018-11, Vol.26 (10), p.920-930

2018

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Cannabinoid CB1 receptor inverse agonist MJ08 stimulates glucose production via hepatic sympathetic innervation in rats

European journal of pharmacology, 2017-11, Vol.814, p.232-239

2017

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A novel orally active microtubule destabilizing agent S-40 targets the colchicine-binding site and shows potent antitumor activity

Cancer letters, 2020-12, Vol.495, p.22-32

2020

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Poly (ADP-ribose) polymerases inhibitor, Zj6413, as a potential therapeutic agent against breast cancer

Biochemical pharmacology, 2016-05, Vol.107, p.29-40

2016

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Development and validation of high-throughput screening assays for poly(ADP-ribose) polymerase-2 inhibitors

Analytical biochemistry, 2014-03, Vol.449, p.188-194

2014

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(+)-Isocryptotanshinone derivatives and its simplified analogs as STAT3 signaling pathway inhibitors

Bioorganic chemistry, 2022-10, Vol.127, p.106015-106015, Article 106015

2022

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CAT3, a novel agent for medulloblastoma and glioblastoma treatment, inhibits tumor growth by disrupting the Hedgehog signaling pathway

Cancer letters, 2016-10, Vol.381 (2), p.391-403

2016

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Cryptotanshinone inhibits esophageal squamous-cell carcinoma in vitro and in vivo through the suppression of STAT3 activation

OncoTargets and therapy, 2019-01, Vol.12, p.883-896

2019

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A novel PI3K/mTOR dual inhibitor XH002 exhibited robust antitumor activity in NSCLC

Journal of drug targeting, 2019-04, Vol.27 (4), p.451-459

2019

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Chlorogenic Acid Prevents UVA-Induced Skin Photoaging through Regulating Collagen Metabolism and Apoptosis in Human Dermal Fibroblasts

Secreted HSP90α-LRP1 Signaling Promotes Tumor Metastasis and Chemoresistance in Pancreatic Cancer

Exploration of the Fluorescent Properties and the Modulated Activities against Sirtuin Fluorogenic Assays of Chromenone-Derived Natural Products

The Characteristics of Hepatic Gsα-cAMP Axis in HSHF Diet-Fed Obese Insulin Resistance Rats and Genetic Diabetic Mice

The PI3K Inhibitor XH30 Enhances Response to Temozolomide in Drug-Resistant Glioblastoma via the Noncanonical Hedgehog Signaling Pathway

ACAT1 deficiency in myeloid cells promotes glioblastoma progression by enhancing the accumulation of myeloid-derived suppressor cells

S-72, a Novel Orally Available Tubulin Inhibitor, Overcomes Paclitaxel Resistance via Inactivation of the STING Pathway in Breast Cancer

YPD-30, a prodrug of YPD-29B, is an oral small-molecule inhibitor targeting PD-L1 for the treatment of human cancer

S1PR1 serves as a viable drug target against pulmonary fibrosis by increasing the integrity of the endothelial barrier of the lung

Sphingosine-1-Phosphate Receptor Subtype 1 (S1P1) Modulator IMMH001 Regulates Adjuvant- and Collagen-Induced Arthritis

Antiproliferative effect of HSP90 inhibitor Y306zh against pancreatic cancer is mediated by interruption of AKT and MAPK signaling pathways

Honokiol prevents lung metastasis of triple-negative breast cancer by regulating polarization and recruitment of macrophages

Re-expression of epigenetically silenced PTPRR by histone acetylation sensitizes RAS-mutant lung adenocarcinoma to SHP2 inhibition

Design, Synthesis, and Biological Evaluation of 4‑Methyl Quinazoline Derivatives as Anticancer Agents Simultaneously Targeting Phosphoinositide 3‑Kinases and Histone Deacetylases

Discovery of Natural Ah Receptor Antagonists from Salvia miltiorrhiza Bunge and Synthesis of Analogs for Tumor Immunotherapy

Chaperone-mediated autophagy degradation of IGF-1Rβ induced by NVP-AUY922 in pancreatic cancer

Bt354 as a new STAT3 signaling pathway inhibitor against triple negative breast cancer

Cannabinoid CB1 receptor inverse agonist MJ08 stimulates glucose production via hepatic sympathetic innervation in rats

A novel orally active microtubule destabilizing agent S-40 targets the colchicine-binding site and shows potent antitumor activity

Poly (ADP-ribose) polymerases inhibitor, Zj6413, as a potential therapeutic agent against breast cancer

Development and validation of high-throughput screening assays for poly(ADP-ribose) polymerase-2 inhibitors

(+)-Isocryptotanshinone derivatives and its simplified analogs as STAT3 signaling pathway inhibitors

CAT3, a novel agent for medulloblastoma and glioblastoma treatment, inhibits tumor growth by disrupting the Hedgehog signaling pathway

Cryptotanshinone inhibits esophageal squamous-cell carcinoma in vitro and in vivo through the suppression of STAT3 activation

A novel PI3K/mTOR dual inhibitor XH002 exhibited robust antitumor activity in NSCLC

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